Division of Biochemistry, Biophysics and Structural Biology
Division of Biochemistry, Biophysics and Structural Biology - Structure of the human Ndc80 kinetochore complex around microtubules
Division of Neurobiology
Division of Neurobiology - Phosphorylation of mTOR in neurons in the striatum
Division of Cell and Developmental Biology
Division of Cell and Developmental Biology - Impaired trafficking of Notch in neoplastic ESCRT mutant Drosophila cells
Heterochromatin dynamics in Saccharomyces cerevisiae
Division of Genetics, Genomics and Development - Heterochromatin dynamics in Saccharomyces cerevisiae
Division of Immunology and Pathogenesis
Division of Immunology and Pathogenesis - Salmonella typhimurium growing within a macrophage

Recent News

Cryo-EM structure of NDH

New research published in Nature from Assistant Adjunct Professor Professor Karen Davies and Associate Professor David Savage reveals the structure of NDH, a protein structure necessary for photosynthesis. This new molecular blueprint will allow researchers to directly test hypotheses of how NDH facilitates sugar production.

“This work will lead to a better understanding of how photosynthesis occurs, which could allow us to improve the efficiency of photosynthesis in plants and other green organisms – potentially boosting the amount of food, and thus biomass, they produce,” said lead researcher Davies.

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Yildiz

A new paper published in Nature from the lab of MCB Associate Professor Ahmet Yildiz shows how the structure of dynein, a family of cytoskeletal motor proteins, determines its directionality. By engineering variants of dynein with altered stalk angles, the researchers uncover why all dyneins move toward only the minus end of a microtubule during cytoskeletal movement.

The research is a collaboration with scientists from the Medical Research Council in the UK and Istanbul Technical University.

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Fletcher & Hariharan

Congratulations to Professors Daniel Fletcher and Iswar Hariharan, two new Miller Professors from MCB! The Miller Professorship award allows UC Berkeley faculty the opportunity to join the interdisciplinary community surrounding the Miller Institute and pursue new research directions.

CasX EM

A new paper published in Nature from the labs of MCB Professors Jennifer Doudna and Eva Nogales reveals the power and potential of the CRISPR-CasX gene editing enzyme. Compared to its well-studied cousins Cas9 and Cas12, CasX is much smaller and may be better shaped for more efficient genetic engineering.

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Chang

Congratulations to MCB & Chemistry Professor Chris Chang, winner of the 2019 Raymond and Beverly Sackler International Prize in Chemistry from Tel Aviv University. This prize is awarded to outstanding young scientists under 45 years of age who exhibit great originality and excellence in their research.

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