Below are articles from various sources about members of MCB and their research.
Congratulations to Associate Professor of MCB, NST & Chemistry Daniel Nomura for winning an ASPIRE Award from the Mark Foundation for Cancer Research! This award "funds high risk, high reward approaches to solving complex problems in cancer research that tend to fall outside the scope of other funding opportunities."
Nomura's lab is mapping hotspots of binding sites in human proteins that have been traditionally considered "undruggable" and developing novel small molecule drugs that bind to those proteins.
Congratulations to MCB Assistant Professor Priya Moorjani, who has been named a 2019 Sloan Research Fellow! The Alfred P. Sloan Foundation awards this fellowship to outstanding early-career researchers and funds $70,000 over two years to fund their research.
Moorjani's lab studies evolutionary history and its impact on human adaptation and disease.
New research published in Nature from Assistant Adjunct Professor Professor Karen Davies and Associate Professor David Savage reveals the structure of NDH, a protein structure necessary for photosynthesis. This new molecular blueprint will allow researchers to directly test hypotheses of how NDH facilitates sugar production.
“This work will lead to a better understanding of how photosynthesis occurs, which could allow us to improve the efficiency of photosynthesis in plants and other green organisms – potentially boosting the amount of food, and thus biomass, they produce,” said lead researcher Davies.
A new paper published in Nature from the lab of MCB Associate Professor Ahmet Yildiz shows how the structure of dynein, a family of cytoskeletal motor proteins, determines its directionality. By engineering variants of dynein with altered stalk angles, the researchers uncover why all dyneins move toward only the minus end of a microtubule during cytoskeletal movement.
The research is a collaboration with scientists from the Medical Research Council in the UK and Istanbul Technical University.
A new paper published in Nature from the labs of MCB Professors Jennifer Doudna and Eva Nogales reveals the power and potential of the CRISPR-CasX gene editing enzyme. Compared to its well-studied cousins Cas9 and Cas12, CasX is much smaller and may be better shaped for more efficient genetic engineering.
Congratulations to MCB & Chemistry Professor Chris Chang, winner of the 2019 Raymond and Beverly Sackler International Prize in Chemistry from Tel Aviv University. This prize is awarded to outstanding young scientists under 45 years of age who exhibit great originality and excellence in their research.
New research from the lab of MCB Professor Marla Feller shows visual stimuli can shape the visual system before eye opening.
These results open up a whole new area of research. “No one has essentially put a mouse in the dark before the eyes open, because they thought it would have no effect,” Feller says. Her next step is to investigate how light exposure before eye opening — which happens in nature for many species of mice — might influence the development of the circuitry within the retina itself.