Department News

News about about MCB faculty, students and staff.

Development of asymmetric inhibition underlying direction selectivity in the retina

How does a neural circuit get wired up to perform specific computations? The Feller lab recently addressed this question by studying the circuit mediates direction selectivity in the retina (Wei et al, Nature, 2010).

Direction-selective neurons, which respond selectively to motion in one direction, have been characterized in visual circuits across many species. In the retina, it has been postulated that the ability to discern the direction of motion of an object required asymmetric wiring between the retinal neurons. However, the mechanisms that instruct this asymmetric wiring during development were completely unknown.

Scientists Find Signals That Make Cell Nucleus Blow up Like a Balloon

Size matters when it comes to the nucleus of a cell and now Professor of Cell and Developmental Biology Rebecca Heald and post-doctoral fellow Daniel L. Levy have discovered the signals that control how big the nucleus gets.

Nuclear size varies not only among different species, but also in different types of cells in the same species and at different times during development. In addition, cancer cells are known to develop larger nuclei as they become more malignant. Screening for cervical cancer, for example, involves looking for grossly distorted nuclei in cervical cells collected during a Pap smear.

"Pathologists look at nuclear size in cancer cells for staging different cancers, but nobody knows what is behind this," said Rebecca Heald, professor of molecular and cell biology at the University of California, Berkeley.

Faculty Award for Excellence in Postdoctoral Mentoring

More than 200 UC Berkeley postdocs, their family and friends, and members of the campus community gathered at the Bancroft Hotel to celebrate postdocs and their important contributions to the campus.

Postdocs offered their own expression of appreciation honoring Rebecca Heald, professor of molecular and cell biology, as the first recipient of the Faculty Award for Excellence in Postdoctoral Mentoring.

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Researchers expand yeast's sugary diet to include plant fiber

University of California, Berkeley, researchers have taken genes from grass-eating fungi and stuffed them into yeast, creating strains that produce alcohol from tough plant material cellulose that normal yeast can't digest.

The feat could be a boon for the biofuels industry, which is struggling to make cellulosic ethanol ethanol from plant fiber, not just cornstarch or sugar economically feasible.

Jamie Cate, associate professor of molecular and cell biology and faculty scientist at Lawrence Berkeley National Laboratory (LBNL) and his UC Berkeley and LBNL colleagues report their success this week in Science Express, a fast-track online publication of the journal Science.