Yildiz
Associate Professor Ahmet Yildiz
Photo: Mark Hanson at Mark Joseph Studios

A new paper published in Nature from the lab of MCB Associate Professor Ahmet Yildiz shows how the structure of dynein, a family of cytoskeletal motor proteins, determines its directionality. By engineering variants of dynein with altered stalk angles, the researchers uncover why all dyneins move toward only the minus end of a microtubule during cytoskeletal movement.

The research is a collaboration with scientists from the Medical Research Council in the UK and Istanbul Technical University.

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