Predicting Patient Response to Cancer Treatments

MCB Adjunct Professor Gary Karpen and his team published a new study recently in the journal Nature Communications -- their findings could lead to a new biomarker for the early stages of tumor development.


Image: The centromeres and kinetochores of a chromosome play critical roles during cell division. In mitosis, microtubule spindle fibers attach to the kinetochores, pulling the chromatids apart. A breakdown in this process causes chromosome instability. Researchers have linked the overexpression of centromere and kinetochore genes to cancer patient outcome after adjuvant therapies. (Credit: Zosia Rostomian/Berkeley Lab)