Professor and biochemist Jennifer Doudna and Professor and biophysicist Eva Nogales led a study that showed how a CRISPR-Cas surveillance complex in the bacterial immune system is able to target specific sites on an RNA molecule for the destruction of invaders.
Photo of Type III CRISPR-Cas complexes were shown to use a thumb-like domain (top right corner) to target specific sites on an RNA molecule for the destruction of invasive nucleic acids -- courtesy of Eva Nogales.