Let the Structural Symphony Begin

"Like other structural biologists, Eva Nogales works in extraordinary times. The University of California, Berkeley, faculty member now has the tools to tackle important questions about cells' molecular machinery that would have been impossible to answer just a few years ago. A recent project with Berkeley colleague Jennifer Doudna, the molecular biologist who co-pioneered the CRISPR–Cas9 gene-editing method, is a case in point..."

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The details of the enzyme RNA polymerase have been intriguing structural biologists for some time. Photo credit: David Bushnell, Ken Westover & Roger Kornberg/Stanford Univ.