Shedding Light on Basic Genetic Mechanisms

A new study from the Patel Lab illustrates the ease with which CRISPR-Cas9 can knock out genes in exotic animals — in this case, an amphipod or sandhopper — to learn how those genes control growth and development.


Scanning electron microscope images of a normal amphipod (top), about one millimeter long, with color-coded hind jumping legs, and an amphipod that has been genetically modified with CRISPR to grow forward-walking legs instead (bottom). (Arnaud Martin image)