Biochemistry, Biophysics and Structural Biology

Faculty
The following is an alphabetical list of active MCB faculty members in the division and brief descriptions of their research. Additional faculty lists are available using the following links:
Emeriti and Professors of the Graduate School | Secondary Divisional Affiliates
Michael Botchan
Dean of Biological Sciences Professor of Biochemistry, Biophysics and Structural Biology
Eukaryote DNA replication and control of S phase
Carlos Bustamante
Howard Hughes Medical Institute Investigator and Raymond and Beverly Sackler Chair and Professor of Biochemistry, Biophysics and Structural Biology
Structural characterization of nucleo-protein assemblies
Jamie H. D. Cate
Professor of Biochemistry, Biophysics and Structural Biology
Molecular Basis for Protein Synthesis by the Ribosome
Christopher Chang
Class of 1942 Chair and Professor of Biochemistry, Biophysics and Structural Biology
Deciphering roles for metals and redox signals in neurobiology, metabolism, and cancer enabled by activity-based sensing and related chemical technologies
Michelle Chang
Professor of Biochemistry, Biophysics and Structural Biology
Enzyme catalysis and metabolic engineering
Kathleen Collins
Walter and Ruth Schubert Family Chair, Professor of Biochemistry, Biophysics and Structural Biology
Biology, biochemistry, and biotechnology of retroelements, retroelement reverse transcriptases, and functional RNAs
Jennifer A. Doudna
Howard Hughes Medical Institute Investigator, Li Ka Shing Chancellor's Chair in Biomedical and Health Sciences and Professor of Biochemistry, Biophysics and Structural Biology
RNA-mediated gene regulation
Britt Glaunsinger
Howard Hughes Medical Institute Investigator and Professor of Biochemistry, Biophysics and Structural Biology
Virology; messenger RNA processing and degradation
Nicholas Ingolia
Associate Professor of Biochemistry, Biophysics and Structural Biology
Molecular basis and physiological roles of the Translational control of gene expression through global and genome-wide analyses
John Kuriyan
Howard Hughes Medical Institute Investigator and Chancellor's Professor of Biochemistry, Biophysics and Structural Biology
Structural and functional studies of signal transduction and DNA replication
Bronwyn Lucas
Assistant Professor of Biochemistry, Biophysics and Structural Biology
In cell structural biology
Michael Marletta
Professor of Biochemistry, Biophysics and Structural Biology
Structure/Function Relationships in Proteins; Enzyme Catalysis; Molecular Mechanisms of Cell Signaling
Susan Marqusee
Professor of Biochemistry, Biophysics and Structural Biology
Determinants of protein structure and folding
Andreas Martin
Howard Hughes Medical Institute Investigator and Associate Professor of Biochemistry, Biophysics and Structural Biology
Energy-dependent proteases and molecular machines
Sabeeha Merchant
Professor of Biochemistry, Biophysics and Structural Biology
Biochemistry of metals; photosynthesis and bioenergy; genomics of algae
Evan Miller
Associate Professor of Biochemistry, Biophysics and Structural Biology
Chemical biology, neuroscience, organic chemistry, fluorescence, imaging
Eva Nogales
Howard Hughes Medical Institute Investigator and Professor of Biochemistry, Biophysics and Structural Biology
Structure-function of macromolecular assemblies: cytoskeleton self-assembly and nucleic acid transactions
Daniel K. Nomura
Professor of Biochemistry, Biophysics and Structural Biology
Using chemoproteomic platforms for drug discovery against the undruggable proteome and incurable diseases
James Nuñez
Assistant Professor of Biochemistry, Biophysics and Structural Biology
Epigenome editing, epigenetic memory and inheritance; CRISPR technology development
Eunyong Park
Assistant Professor of Biochemistry, Biophysics and Structural Biology
Structure and mechanism of membrane transport proteins; cryo-EM; biochemistry; biophysics
Daniel Portnoy
Distinguished Professor of Biochemistry, Biophysics and Structural Biology
Molecular and cellular basis of microbial pathogenesis
Donald Rio
Professor of Biochemistry, Biophysics and Structural Biology
Molecular genetics; transposable elements; RNA splicing
David Savage
Associate Professor of Biochemistry, Biophysics and Structural Biology
Synthetic biology and metabolism.
Alanna Schepartz
CZ and Irmgard Distinguished Chair of Chemistry, Professor of Biochemistry, Biophysics and Structural Biology
Chemical and synthetic biology; how cellular molecules and machines function and how this information can be used to design new and useful molecules.
Robert Tjian
Howard Hughes Medical Institute President and Professor of Biochemistry, Biophysics and Structural Biology
Eukaryotic molecular biology; biochemistry
Ross Wilson
Assistant Adjunct Professor of Biochemistry, Biophysics and Structural Biology
Molecular mechanisms and therapeutic delivery of genome editing enzymes
Ahmet Yildiz
Professor of Biochemistry, Biophysics and Structural Biology
Structural mechanism of molecular motors. High resolution imaging of subcellular structures
Qiang Zhou
Professor of Biochemistry, Biophysics and Structural Biology
Biochemistry of HIV gene expression and transcriptional elongation
Roberto Zoncu
Associate Professor of Biochemistry, Biophysics and Structural Biology
How organelles sense nutrients and regulate cellular growth
Emeriti and Professors of the Graduate School
Bruce N. Ames
Professor Emeritus of Biochemistry, Biophysics and Structural Biology
Mechanisms of aging. Mitochondrial decay in aging. Oxidants and antioxidants in DNA damage. Micronutrient deficiencies and DNA damage. Chronic inflammation and Cancer.
Giovanna Ferro-Luzzi Ames
Professor Emerita of Biochemistry, Biophysics and Structural Biology
Bacterial molecular biology; membranes
Michael Chamberlin
Professor Emeritus of Biochemistry, Biophysics and Structural Biology
Nucleic acids; gene expression
Robert Glaeser
Professor Emeritus of Biochemistry, Biophysics and Structural Biology
Cryo-EM of multiprotein complexes; membrane proteins; structural biology; biophysics; advancing the capabilities of high-resolution cryo-EM in biology.
Caroline Kane
Professor Emerita of Biochemistry, Biophysics and Structural Biology
Eukaryotic gene regulation during transcript elongation
Judith Klinman
Professor Emerita of Biochemistry, Biophysics and Structural Biology
Principles of catalytic and regulatory mechanisms in enzyme-catalyzed reactions
Stuart Linn
Professor Emeritus of Biochemistry, Biophysics and Structural Biology
Enzymology of DNA metabolism
Hiroshi Nikaido
Professor of the Graduate School Division of Biochemistry, Biophysics and Structural Biology
Membrane biochemistry; bacterial physiology
Edward Penhoet
Professor Emeritus of Biochemistry, Biophysics and Structural Biology
Jeremy Thorner
Distinguished Professor Emeritus of Biochemistry, Biophysics and Structural Biology
Signal transduction mechanisms; biochemistry; molecular genetics; cell biology
David Zusman
Professor Emeritus of Biochemistry, Biophysics and Structural Biology
Microbial development; molecular genetics
Secondary Divisional Affiliates
The following faculty have a secondary affiliation with the Biochemistry, Biophysics and Structural Biology division.
Stephen Brohawn
Assistant Professor of Neurobiology
Molecular basis of sensory transduction and cellular electrical signaling
James Hurley
Kirsch Springer Chair in Biological Sciences and Professor of Cell Biology, Development and Physiology
Structural membrane biology
G. Steven Martin
Professor Emeritus of Cell Biology, Development and Physiology
Cell biology; tumor virology
Michael Rape
Howard Hughes Medical Institute Investigator and Professor of Cell Biology, Development and Physiology
Protein ubiquitination, degradation and the control of cell division and differentiation
Randy Schekman
Howard Hughes Medical Institute Investigator and Professor of Cell Biology, Development and Physiology
Organelle assembly; protein transport