A selection of papers published by MCB graduate students

Ansaldo E, Slayden LC, Ching KL, Koch MA, Wolf NK, Plichta DR, Brown EM, Graham DB, Xavier RJ, Moon JJ, Barton GM. (2019). Akkermansia muciniphila induces intestinal adaptive immune responses during homeostasisScience. 364:1179-1184. 

Antoine MW*, Langberg T*, Schnepel P*, Feldman DE. (2019). Increased excitation-inhibition ratio stabilizes synapse and circuit excitability in four autism mouse models.  Neuron.  101(4): pii: S0896-6273: 31126-7.  PMC6733271 

Bard JAM, Bashore C, Dong KC, and Martin A. (2019). The 26S Proteasome utilizes a kinetic gateway to prioritize substrate degradationCell. 177, 286-298.

Benthall KN, Cording KR, Agopyan-Miu AHCW, Wong CD, Chen EY, Bateup HS. (2021). Loss of Tsc1 from striatal direct pathway neurons impairs endocannabinoid-LTD and enhances motor routine learning. Cell Reports. 36(6):109511. 

Brothers M, Rine J. (2019). Mutations in the PCNA DNA polymerase clamp of Saccharomyces cerevisiae reveal complexities of the cell cycle and ploidy on heterochromatin assembly. Genetics. Oct;213(2):449-463.

Carroll EC, Latorraca NR, Lindner JM, Maguire BC, Pelton JG, Marqusee S. (2021). Mechanistic basis for ubiquitin modulation of a protein energy landscape. Proc Natl Acad Sci U S A. Mar 23;118(12):e2025126118. PMID: 33723075

Chen S, Sun S, Schaffer D, and He L. (2019). CRISPR-READI: Efficient generation of knock-in mice by CRISPR RNP Electroporation and AAV Donor InfectionCell reports. Jun 25;27(13):3780-3789.e4.

Cheng Z*, Otto GM*, Powers EN, Keskin A, Mertins P, Carr SA, Jovanovic M, Brar GA. (2018). Pervasive, coordinated protein level changes driven by transcript isoform switching during meiosis. Cell. (*equal contributions)

Cofsky JC, Karandur D, Huang CJ, Witte IP, Kuriyan J, Doudna JA. (2020). CRISPR-Cas12a exploits R-loop asymmetry to form double-strand breaks. Elife. Jun 10;9:e55143. PMID: 32519675; PMCID: PMC7286691

Eshun-Wilson L, Zhang R, Portran D, Nachury MV, Toso D, Lohr T, Vendruscolo M, Bonomi M, Fraser JS, Nogales E. (2019). Effects of α-tubulin acetylation on microtubule structure and stability. PNAS 116, 10366-10371.

Hesser CR, Karijolich J, Dominissini D, He C, Glaunsinger BA. (2018). N6-methyladenosine modification and the YTHDF2 reader protein play cell type specific roles in lytic viral gene expression during Kaposi's sarcoma-associated herpesvirus infection. PLoS Pathog. Apr 16;14(4):e1006995

Hill RZ, Morita T, Hoffman B, Lumpkin EA, Brem RB, Bautista DM. (2018). The signaling lipid sphingosine 1-phosphate regulates mechanical painElife. 7:e33285.

Ireland EV, Woznica A, King N. (2020). Synergistic cues from diverse bacteria enhance multicellular development in a choanoflagellateApplied and Environmental Microbiology, 86(11).

Lamothe R, Costantino L, Koshland DE. (2020). The spatial regulation of condensin activity in chromosome condensationGenes & Development.

Lutes LK, Steier Z, McIntyre LL, Pandey S, Kaminski J, Hoover AR, Ariotti S, Streets A, Yosef N, Robey EA. (2021). T cell self-reactivity during thymic development dictates the timing of positive selection. Elife. Apr 22;10:e65435.

McSwiggen DT, Hansen AS, Teves SS, Marie-Nelly H, Hao Y, Heckert AB, Umemoto KK, Dugast-Darzacq C, Tjian R, Darzacq X. (2019). Evidence for DNA-mediated nuclear compartmentalization distinct from phase separation. Elife. May 7;8. pii: e47098. PMID:31038454

Mena EL, Jevtić P, Greber BJ, Gee CL, Lew BG, Akopian D, Nogales E, Kuriyan J, Rape M. (2020). Structural basis for dimerization quality control. Nature 586(7829):452-456.

Meng G, Liang Y, Sarsfield S, Jiang WC, Lu R, Dudman JT, Aponte Y, Ji N. (2019). High-throughput synapse-resolving two-photon fluorescence microendoscopy for deep-brain volumetric imaging in vivoElife. e40805.

Mills WK, Lee YCG, Kochendoerfer AM, Dunleavy EM, and Karpen GH. (2019). RNA from a simple-tandem repeat is required for sperm maturation and male fertility in Drosophila melanogaster. eLife. Nov 5;8. PMID 31687931

Nichols RJ, LaFrance B, Phillips NR, Radford DR, Oltrogge LM, Valentin-Alvarado LE, Bischoff AJ, Nogales E, Savage DF. (2021). Discovery and characterization of a novel family of prokaryotic nanocompartments involved in sulfur metabolism. Elife. 10:e59288.

Nicolai CJ, Raulet DJ. (2020). Killer cells add fire to fuel immunotherapyScience. 368:943-944.

Pedersen RTA, Drubin DG. (2019). Type 1 myosins anchor actin assembly to the plasma membrane during clathrin-mediated endocytosisJ. Cell Biol.  218(4):1138-1147. PMID: 30659101

Pulos-Holmes MC, Srole DN, Juarez MG, Lee AS, McSwiggen DT, Ingolia NT, Cate JH. (2019). Repression of ferritin light chain translation by human eIF3. Elife. 8. pii: e48193. PMID: 31414986; PMCID: PMC672179.

Shams A, Higgins SA, Fellmann C, Laughlin TG, Oakes BL, Lew R, Kim S, Lukarska M, Arnold M, Staahl BT, Doudna JA, Savage DF. (2021). Comprehensive deletion landscape of CRISPR-Cas9 identifies minimal RNA-guided DNA-binding modules. Nat Commun. Sep 27;12(1):5664. PMID: 34580310

Tresenrider A, Morse K, Jorgensen V, Chia M, Liao H, Van Werven F, Ünal E. (2021). Integrated genomic analysis reveals key features of long undecoded transcript isoform (LUTI)-based gene repression. Molecular Cell. Mar 26;S1097-2765(21)00181-7.