Capturing an Enzyme that Plays Key Roles in Aging, Cancer

Professor of Biochemistry, Biophysics and Structural Biology Kathy Collins, in collaboration with researchers at UCLA, has produced the clearest image of telomerase to date. This enzyme plays a significant role in aging and most cancers, but until recently many aspects of the enzyme’s structure could not be clearly seen.

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Image is a rendering of telomerase, showing the enzyme’s various subunits. Image credit: Feigon and Jiang.