MCB230

	WEEK 6 L1: Introduction to the Cell Cycle PPT PDF L2: Cytoskeleton Basics and Microtubule Dynamics PPT (warning:huge) PDF
1	Bacterial ancestry of actin and tubulin (review)
2	Microtubule Polymerization Dynamics (review)
3	The spindle: a dynamic assembly of microtubules and motors (review)
4	Kin I Kinesins Are Microtubule-Destabilizing Enzymes

	DISCUSSION PAPERS:
5	Identification of pathways regulating cell size and cell-cycle progression by RNAi
	SUPPLEMENTAL MATERIAL AT: http://www.nature.com/nature/journal/v439/n7079/suppinfo/nature04469.html
6	RNA interference pinpoints regulators of cell size and the cell cycle (minireview)

	WEEK 7 L3: Microtubule Structure, Organizers, and Motors PPT PDF L4: Actin and Myosin PPT PDF
7	High-Resolution Model of the Microtubule
8	Molecular motors (review)
9	Dynamics and mechanics of the microtubule plus end (review)
10	Centrosome Duplication: A Centriolar Pas de Deux (review)
11	A single myosin head moves along an actin filament with regular steps of 5.3 nanometres
12	Control of cell shape in bacteria: helical, actin-like filaments in bacillus subtilis
13	Molecular dynamics of cyclically contracting insect flight muscle in vivo

	DISCUSSION PAPER:
14	Control of microtubule dynamics by the antagonistic activities of XMAP215 and XKCM1 in Xenopus egg extracts

	WEEK 8 L5: Chromosomes and the Cell Cycle: Interphase PPT PDF L6: Chromosomes and the Cell Cycle: Nuclear Organization and Mitosis PPT PDF
15	Beyond the Sequence: Cellular Organization of Genome Function (review)
16	At the heart of the chromosome: SMC proteins in action (review)
17	Noncoding RNAs in gene silencing (review)
18	Chromatin Modifications and Their Function (review)
19	Propagation of centromeric chromatin requires exit from mitosis
20	Perturbation of Nuclear Architecture by Long-Distance Chromosome Interactions
	DISCUSSION PAPER:
21	Loss of the Suv39h Histone Methyltransferases Impairs Mammalian Heterochromatin and Genome Stability

	WEEK 9 L7: Chromosomes and the Cell Cycle: Centromeres and Spinles PPT PDF L8: Chromosomes and the Cell Cycle: Anaphase and Cytokinesis PPT PDF
22	The spindle: a dynamic assembly of microtubules and motors (review)
23	Chromosomes Can Congress to the Metaphase Plate Before Biorientation
24	The Xenopus Chromokinesin Xkid Is Essential for Metaphase Chromosome Alignment and Must Be Degraded to Allow Anaphase Chromosome Movement
25	A cytokinesis furrow is positioned by two consecutive signals
26	Importin b Is a Mitotic Target of the Small GTPase Ran in Spindle Assembly
27	Formation of a Dynamic Kinetochore-Microtubule Interface through Assembly of the Dam1 Ring Complex
	DISCUSSION PAPER:
28	Sister-chromatid separation at anaphase onset is promoted by cleavage of the cohesin subunit Scc1
	News and Views: Cell cycle: A snip separates sisters
	EXTRAS:
29	Cytokinesis in Eukaryotes (review)
30	Functional genomic analysis of cell division in C. elegans using RNAi of genes on chromosome III

	WEEK 10 L9: Regulation of the Cell Cycle: Mitosis PPT PDF L10: Regulation of the Cell Cycle: G1/S and Checkpoints PPT PDF
31	Multiple levels of cyclin specificity in cell-cycle control (review)
32	Cyclin specificity in the phosphorylation of cyclin-dependent kinase substrates
33	The anaphase promoting complex/cyclosome: a machine designed to destroy (review)
34	Mammalian G1- and S-phase checkpoints in response to DNA damage (review)
35	Microtubule capture by CENP-E silences BubR1-dependent mitotic checkpoint signaling
	DISCUSSION PAPER:
36	The roles of Fzy/Cdc20 and Fzr/Cdh1 in regulating the destruction of cyclin B in space and time
	EXTRAS:
37	A tense time for the nuclear envelope (minireview)
38	Hartwell Nobel Lecture
39	Nurse Nobel Lecture
40	The reversibility of mitotic exit in vertebrate cells