New research from the lab of MCB Assistant Professor Polina Lishko describes how flagellar regulatory nanodomains of human sperm are critical to sperm fertility. Hv1 proton channels in those nanodomains are distributed asymmetrically along bilateral flagellar lines to provide the structural basis for flagellar rotation.

The research was published this week in Cell Reports and is a collaboration between the Lishko lab and the lab of Ke Xu, an Assistant Professor in the Department of Chemistry.


Image credit: Miller et al., Cell Reports.