Meyer Lab / Publications

Crane, E., Bian, Q., McCord, R.P., Lajoie, B.R., Wheeler, B. S., Ralston, E.J., Uzawa, S., Dekker, J., Meyer, B.J. (2015) Condensin-driven remodelling of X

chromosome topology during dosage compensation. Nature, 1 June 2015 doi:10.1038/nature14450 [PDF]

Farboud, B., Meyer, B.J. (2015) Dramatic Enhancement of Genome Editing by CRISPR/Cas9 Through Improved Guide RNA Design. Genetics, February

18, 2015 genetics.115.175166 [PDF]

Severson, A., Meyer, B.J. (2014) Divergent kleisin subunits of cohesin specify mechanisms to tether and release meiotic chromosomes. eLife

2014;10.7554/eLife.03467 [PDF]

Libuda, D., Uzawa, S., Meyer, B.J., Villeneuve, A. (2013) Meiotic chromosome structures constrain and respond to designation of crossover sites.

Nature 502, 703-706 (31 October 2013) [PDF]

Maxwell, C., Kruesi, W.S.., Core, L., Kurhanewicz, N., Waters, C., Lewarch, C., Antoshechkin, A., Lis, J., Meyer, B.J., Baugh, L.R.. (2014) Pol II Docking and

Pausing at Growth and Stress Genes in C. elegans. Cell Reports Volume 6, Issue 3, p455-466, 13 February 2014 [PDF]

Pferdehirt, R.R., Meyer, B.J. (2013) SUMOylation is essential for sex-specific assembly and function of the Caenorhabditis elegans dosage compensation

complex on X chromosomes. PNAS 2013; doi:10.1073/pnas.1315793110 [PDF]

Lo, T.W., Pickle, C.S., Lin, S., Ralston, E.J., Gurling, M., Schartner, C.M., Bian, Q., Doudna, J.A., Meyer, B.J. (2013) Precise and Heritable Genome Editing in

Evolutionarily Diverse Nematodes Using TALENs and CRISPR/Cas9 to Engineer Insertions and Deletions. Genetics 195; 331-348. [PDF]

Kruesi, W.S., Core, L.J., Waters, C.T., Lis, J.T., Meyer, B.J. (2013) Condensin controls recruitment of RNA polymerase II to achieve nematode

X-chromosome dosage compensation. eLife 2013; 2:e00808. [PDF]

Farboud, B., Nix, P., Jow, M.M., Gladden, J.M., Meyer, B.J. (2013) Molecular antagonism between X-chromosome and autosome signals determines

nematode sex. Genes & Development 27, 1159-1178. [PDF] [Supp.PDF]

Wood AJ*, Lo TW*, Zeitler B*, Pickle CS, Ralston EJ, Lee AH, Amora R, Miller JC, Leung E, Meng X, Zhang L, Rebar EJ, Gregory PD, Urnov FD, Meyer BJ.

(2011) Targeted genome editing across species using ZFNs and TALENs. Science 333, 307. *These authors contributed equally to this work. [PDF]

[Supp.PDF]

Pferdehirt, R. R., Kruesi, W. S., Meyer, B. J. (2011) An MLL/COMPASS Subunit Functions in the C. elegans Dosage Compensation Complex to Target X

Chromosomes for Transcriptional Regulation of Gene Expression. Genes & Development 25, 499-515. [PDF] [Supp.PDF]

Meyer, B. J. (2010) Targeting X chromosomes for repression. Current Opinion in Genetics & Development 20, 179-189. [PDF]

Wood, A. J., Severson, A. F., Meyer, B. J. (2010) Condensin and Cohesin Complexity: the Expanding Repertoire of Functions. Nat. Rev. Genet. 11,

391-404. [PDF]

Youds, J. L., Mets, D. G., Mcllwraith, M. J., Martin, J. S., Ward, J. D., O'Neil, N. J., Rose, A. M., West, S. C., Meyer, B. J., Boulton, S. J. (2010) RTEL-1 Enforces

Meiotic Crossover Interference and Homeostasis. Science 327, 1254-1258. [PDF]

Mets, D. G., Meyer, B. J. (2009) A Condensin Complex Regulates DSB Distribution and thus Crossover Frequency by Controlling Chromosome

Structure. Cell 139, 73-86. [PDF] [Supp.PDF]

Severson, A.F., Ling, L., van Zuylen, V., Meyer, B.J. (2009) The axial element protein HTP-3 promotes cohesin loading and meiotic axis assembly in C.

elegans to implement the meiotic program of chromosome segregation. Genes & Development 23 (15), 1763-1778. [PDF] [Supp.PDF]

Jans, J. Gladden, J. M., Ralston, E. J., Pickle, C. S., Michel, A. H., Pferdehirt, R. R., Eisen, M. B., Meyer, B. J. (2009) A condensin-like dosage compensation

complex acts at a distance to control expression throughout the genome. Genes & Development 23 (5), 602-618. [PDF] [Supp.PDF]

Csankovszki, G., Collette, K., Spahl, K., Carey, J., Snyder, M., Petty, E., Patel, U., Tabuchi, T., Liu, H., McLeod, I., Thompson, J., Sarkesik, A., Yates, J., Meyer,

B.J., Hagstrom, K. (2009) Three distinct condensin complexes control C. elegans chromosome dynamics. Current Biology 19 (1), 9-19. [PDF] [Supp.PDF]

Reiner, D.J., Ailion, M., Thomas, J.H., Meyer, B.J. (2008) C. elegans anaplastic lymphoma kinase ortholog SCD-2 controls dauer formation by modulating

TGF-beta signaling. Current Biology 18(15), 1101-9. [PDF] [Supp.PDF]

Tsai, C.J., Mets, D.G., Albrecht, M.R., Nix, P., Chan, A., Meyer, B.J. (2008) Meiotic crossover number and distribution are regulated by a dosage

compensation protein that resembles a condensin subunit. Genes & Development 22, 194-211. [PDF] [Supp.PDF]

Gladden, J.M., Meyer, B.J. (2007) A ONECUT Homeodomain Protein Communicates X Chromosome Dose to Specify Caenorhabditis elegans Sexual

Fate by Repressing a Sex Switch Gene. Genetics 177 (3), 1621-1637. [PDF]

Gladden, J.M., Farboud, B., Meyer, B.J. (2007) Revisiting the X:A Signal That Specifies Caenorhabditis elegans Sexual Fate. Genetics 177 (3), 1639-1654.

[PDF]

McDonel, P.E., Jans, J., Peterson, B.K., Meyer, B.J. (2006) Clustered DNA motifs mark X chromosomes for repression by a dosage compensation

complex. Nature 444, 614-618. [PDF]

Chu, D.S., Liu, H., Nix, P., Wu, T.F., Ralston, E.J., Yates, J.R., Meyer, B.J. (2006) Sperm chromatin proteomics identifies evolutionarily conserved fertility

factors. Nature 443, 101-105. [PDF]

Powell, J.R., Jow, M.M., Meyer, B.J. (2005) The T-box transcription factor SEA-1 is an autosomal element of the X:A signal that determines C. elegans

sex. Dev. Cell 9 (3), 339-349. [PDF]

Meyer, B. J. X-Chromosome dosage compensation (June 25, 2005), WormBook, ed. The C. elegans Research Community, WormBook,

doi/10.1895/wormbook.1.8.1, http://www.wormbook.org. [PDF]

Skop, A., Liu, H., Yates, J., Meyer, B., Heald, R. (2004) Dissection of the mammalian midbody proteome reveals conserved cytokinesis mechanisms.

Science 305, 61-66. [PDF]

Csankovszki, G., McDonel, P. and Meyer, B.J. (2004) Recruitment and Spreading of the C. elegans Dosage Compensation Complex along X

Chromosomes. Science 303, 1182-1185. [PDF]

Chan, R.C., Severson, A.F., Meyer, B.J. (2004) Condensin Restructures Chromosomes in preparation for Meiotic Divisions. J. Cell Biology 167, 613-625.

[PDF]

Yonker, S.A. and Meyer, B.J. (2003) Recruitment of C. elegans Dosage Compensation Proteins for Gene-Specific Versus Chromosome-Wide

Repression. Development 130, 6519-6532. [PDF]

Chan, R., Chan, A., Jeon, M., Wu, T., Pasqualone, D., Rougvie, A., Meyer, B. (2003) Chromosome cohesion is regulated by C. elegans TIM-1, a paralog of

the clock protein TIMELESS. Nature 423, 1002-1009. [PDF]

Luz, J.G., Hassig, C.A., Pickle, C., Godzik, A., Meyer, B.J., Wilson, I.A. (2003) XOL-1, Primary Determinant of Sexual Fate in C. elegans Is a GHMP Kinase

Family Member and a Structural Prototype for a New Class of Developmental Regulators. Genes Dev. 17, 977-990. [PDF]

Chu, D.S., Dawes, H.E., Lieb, J.D., Chan, R.C., Kuo, A.F., and Meyer B.J. (2002) A Molecular Link between Gene-Specific and Chromosome-Wide

Transcriptional Repression. Genes Dev. 16, 796-805. [PDF]

Hagstrom, K., Holmes, V., Cozzarelli, N., and Meyer, B.J. (2002) C. elegans Condensin Promotes Mitotic Chromosome Architecture, Centromere

Organization, and Sister Chromatid Segregation during Mitosis and Meiosis. Genes Dev. 16, 729-742. [PDF]

Howe, M., McDonald, K., Albertson, D., and Meyer, B.J. (2001) HIM-10 is required for kinetochore structure and function on C. elegans holocentric

chromosomes. J. Cell Biol. 153, 1227-1238. [PDF]

Lieb, J.D., Oritz de Solorzano, C., Rodriguez, E.G., Jones, A., Angelo, M. Lockett, S. and Meyer, B.J. (2000) The C. elegans Dosage Compensation

Machinery is Recruited to X-Chromosome DNA Attached to an Autosome. Genetics 156, 1603-1621. [PDF]

Meyer BJ. Mechanisms of sex determination and X-chromosome dosage compensation. Genetics, Volume 220, Issue 2, February 2022, iyab197,

doi.org/10.1093/genetics/iyab197. [PDF]

Ghosh RP, Meyer BJ. Spatial Organization of Chromatin: Emergence of Chromatin Structure During Development. Annu Rev Cell Dev Biol. 2021 Jul 6. doi:

10.1146/annurev-cellbio-032321-035734. Epub ahead of print. PMID: 34228506. [PDF]

Krassovsky K, Ghosh RP, Meyer BJ. Genome-wide profiling reveals functional interplay of DNA sequence composition, transcriptional activity, and nucleosome

positioning in driving DNA supercoiling and helix destabilization in C. elegans. Genome Res. 2021 Jun 24;31(7):1187–202. doi: 10.1101/gr.270082.120. Epub ahead of

print. PMID: 34168009; PMCID: PMC8256864. [PDF]

Farboud, B., Novak, C.S., Nicoll, M., Quiogue, A., Meyer, B.J. (2020). Dose-dependent action of the RNA binding protein FOX-1 to relay X-Chromosome number and

determine C. elegans sex. eLife 2020;9:e62963. doi: 10.7554/eLife.62963. [PDF]

Bian, Q., Anderson, E.A., Yang, Q., Meyer, B.J. (2020). Histone H3K9 methylation promotes formation of genome compartments in Caenorhabditis elegans via

chromosome compaction and perinuclear anchoring. PNAS 117 (21) 11459-11470. doi.org/10.1073/pnas.2002068117. [PDF]

Anderson, E.A., Frankino, P.A., Higuchi-Sanabria, R., Yang, Q., Bian, Q., Podshivalova, K., Shin, A., Kenyon, C., Dillin, A., Meyer, B.J. (2019). X Chromosome Domain

Architecture Regulates Caenorhabditis elegans Lifespan but Not Dosage Compensation. Developmental Cell (Epub 5 September 2019). [PDF]

Farboud, B., Severson, A.F., Meyer, B.J. (2019). Strategies for Efficient Genome Editing Using CRISPR-Cas9. Genetics 211; 431-457. doi:

doi.org/10.1534/genetics.118.301775. [PDF]

Yin, D., Schwarz, E.M., Thomas, C.G., Felde, R.L., Korf, I.F., Cutter, A.D., Schartner, C.M., Ralston, E.J., Meyer, B.J., Haag, E.S. (2018). Rapid Genome Shrinkage in a

Self-Fertile Nematode Reveals Sperm Competition Proteins. Science 359: 55-61. DOI: 10.1126/science.aao0827 PMID: 29302007 PMCID: PMC5789457 [PDF]

Bian, Q., Anderson, E.C., Brejc, K., Meyer, B.J. (2018). Dynamic Control of Chromosome Topology and Gene Expression by a Chromatin Modification. Cold Spring

Harb Symp Quant Biol. pii: 034439. doi: 10.1101/sqb.2017.82.034439. [Epub ahead of print] [PDF]

Meyer, B.J. (2018). Sex and death: from cell fate specification to dynamic control of X-chromosome structure and gene expression. Molecular Biology of the Cell 29;

2603-2799. doi.org/10.1091/mbc.E18-06-0397. 1 November 2018. [PDF]

Meyer, B.J. (2018). On Sex and Death. Bulletin of the American Academy of Arts & Sciences. Summer 2018. [PDF]

Brejc, K., Bian, Q., Uzawa, S., Wheeler, B.J., Anderson, E.C., King, D.S., Kranzusch, P.J., Preston, C.G., Meyer B.J. (2017) Dynamic Control of X Chromosome

Conformation and Repression by a Histone H4K20 Demethylase. Cell, 2017 Sep 21;171(1):85-102.e23. doi: 10.1016/j.cell.2017.07.041. Epub 2017 Aug 31. PubMed

PMID: 28867287. [PDF]

Wheeler BS, Anderson E, Frøkjær-Jensen C, Bian Q, Jorgensen E, Meyer BJ. (2016) Chromosome-wide mechanisms to decouple gene expression from gene dose

during sex-chromosome evolution. eLife, 2016 August 30;5 [PDF]

Crane, E., Bian, Q., McCord, R.P., Lajoie, B.R., Wheeler, B. S., Ralston, E.J., Uzawa, S., Dekker, J., Meyer, B.J. (2015) Condensin-driven remodelling of X chromosome

topology during dosage compensation. Nature, 1 June 2015 doi:10.1038/nature14450 [PDF]

Farboud, B., Meyer, B.J. (2015) Dramatic Enhancement of Genome Editing by CRISPR/Cas9 Through Improved Guide RNA Design. Genetics, February 18, 2015

genetics.115.175166 [PDF]

Severson, A., Meyer, B.J. (2014) Divergent kleisin subunits of cohesin specify mechanisms to tether and release meiotic chromosomes. eLife

2014;10.7554/eLife.03467 [PDF]

Libuda, D., Uzawa, S., Meyer, B.J., Villeneuve, A. (2013) Meiotic chromosome structures constrain and respond to designation of crossover sites.

Nature 502, 703-706 (31 October 2013) [PDF]

Maxwell, C., Kruesi, W.S.., Core, L., Kurhanewicz, N., Waters, C., Lewarch, C., Antoshechkin, A., Lis, J., Meyer, B.J., Baugh, L.R.. (2014) Pol II Docking and Pausing at

Growth and Stress Genes in C. elegans. Cell Reports Volume 6, Issue 3, p455-466, 13 February 2014 [PDF]

Pferdehirt, R.R., Meyer, B.J. (2013) SUMOylation is essential for sex-specific assembly and function of the Caenorhabditis elegans dosage compensation complex on X

chromosomes. PNAS 2013; doi:10.1073/pnas.1315793110 [PDF]

Lo, T.W., Pickle, C.S., Lin, S., Ralston, E.J., Gurling, M., Schartner, C.M., Bian, Q., Doudna, J.A., Meyer, B.J. (2013) Precise and Heritable Genome Editing in Evolutionarily

Diverse Nematodes Using TALENs and CRISPR/Cas9 to Engineer Insertions and Deletions. Genetics 195; 331-348. [PDF]

Kruesi, W.S., Core, L.J., Waters, C.T., Lis, J.T., Meyer, B.J. (2013) Condensin controls recruitment of RNA polymerase II to achieve nematode X-chromosome dosage

compensation. eLife 2013; 2:e00808. [PDF]

Farboud, B., Nix, P., Jow, M.M., Gladden, J.M., Meyer, B.J. (2013) Molecular antagonism between X-chromosome and autosome signals determines nematode sex.

Genes & Development 27, 1159-1178. [PDF] [Supp.PDF]

Wood AJ*, Lo TW*, Zeitler B*, Pickle CS, Ralston EJ, Lee AH, Amora R, Miller JC, Leung E, Meng X, Zhang L, Rebar EJ, Gregory PD, Urnov FD, Meyer BJ. (2011) Targeted

genome editing across species using ZFNs and TALENs. Science 333, 307. *These authors contributed equally to this work. [PDF] [Supp.PDF]

Pferdehirt, R. R., Kruesi, W. S., Meyer, B. J. (2011) An MLL/COMPASS Subunit Functions in the C. elegans Dosage Compensation Complex to Target X Chromosomes

for Transcriptional Regulation of Gene Expression. Genes & Development 25, 499-515. [PDF] [Supp.PDF]

Meyer, B. J. (2010) Targeting X chromosomes for repression. Current Opinion in Genetics & Development 20, 179-189. [PDF]

Wood, A. J., Severson, A. F., Meyer, B. J. (2010) Condensin and Cohesin Complexity: the Expanding Repertoire of Functions. Nat. Rev. Genet. 11, 391-404. [PDF]

Youds, J. L., Mets, D. G., Mcllwraith, M. J., Martin, J. S., Ward, J. D., O'Neil, N. J., Rose, A. M., West, S. C., Meyer, B. J., Boulton, S. J. (2010) RTEL-1 Enforces Meiotic

Crossover Interference and Homeostasis. Science 327, 1254-1258. [PDF]

Mets, D. G., Meyer, B. J. (2009) A Condensin Complex Regulates DSB Distribution and thus Crossover Frequency by Controlling Chromosome Structure. Cell 139,

73-86. [PDF] [Supp.PDF]

Severson, A.F., Ling, L., van Zuylen, V., Meyer, B.J. (2009) The axial element protein HTP-3 promotes cohesin loading and meiotic axis assembly in C. elegans to

implement the meiotic program of chromosome segregation. Genes & Development 23 (15), 1763-1778. [PDF] [Supp.PDF]

Jans, J. Gladden, J. M., Ralston, E. J., Pickle, C. S., Michel, A. H., Pferdehirt, R. R., Eisen, M. B., Meyer, B. J. (2009) A condensin-like dosage compensation complex acts at

a distance to control expression throughout the genome. Genes & Development 23 (5), 602-618. [PDF] [Supp.PDF]

Csankovszki, G., Collette, K., Spahl, K., Carey, J., Snyder, M., Petty, E., Patel, U., Tabuchi, T., Liu, H., McLeod, I., Thompson, J., Sarkesik, A., Yates, J., Meyer, B.J.,

Hagstrom, K. (2009) Three distinct condensin complexes control C. elegans chromosome dynamics. Current Biology 19 (1), 9-19. [PDF] [Supp.PDF]

Reiner, D.J., Ailion, M., Thomas, J.H., Meyer, B.J. (2008) C. elegans anaplastic lymphoma kinase ortholog SCD-2 controls dauer formation by modulating TGF-beta

signaling. Current Biology 18(15), 1101-9. [PDF] [Supp.PDF]

Tsai, C.J., Mets, D.G., Albrecht, M.R., Nix, P., Chan, A., Meyer, B.J. (2008) Meiotic crossover number and distribution are regulated by a dosage compensation protein

that resembles a condensin subunit. Genes & Development 22, 194-211. [PDF] [Supp.PDF]

Gladden, J.M., Meyer, B.J. (2007) A ONECUT Homeodomain Protein Communicates X Chromosome Dose to Specify Caenorhabditis elegans Sexual Fate by

Repressing a Sex Switch Gene. Genetics 177 (3), 1621-1637. [PDF]

Gladden, J.M., Farboud, B., Meyer, B.J. (2007) Revisiting the X:A Signal That Specifies Caenorhabditis elegans Sexual Fate. Genetics 177 (3), 1639-1654. [PDF]

McDonel, P.E., Jans, J., Peterson, B.K., Meyer, B.J. (2006) Clustered DNA motifs mark X chromosomes for repression by a dosage compensation complex. Nature 444,

614-618. [PDF]

Chu, D.S., Liu, H., Nix, P., Wu, T.F., Ralston, E.J., Yates, J.R., Meyer, B.J. (2006) Sperm chromatin proteomics identifies evolutionarily conserved fertility factors. Nature

443, 101-105. [PDF]

Powell, J.R., Jow, M.M., Meyer, B.J. (2005) The T-box transcription factor SEA-1 is an autosomal element of the X:A signal that determines C. elegans sex. Dev. Cell 9 (3),

339-349. [PDF]

Meyer, B. J. X-Chromosome dosage compensation (June 25, 2005), WormBook, ed. The C. elegans Research Community, WormBook, doi/10.1895/wormbook.1.8.1,

http://www.wormbook.org. [PDF]

Skop, A., Liu, H., Yates, J., Meyer, B., Heald, R. (2004) Dissection of the mammalian midbody proteome reveals conserved cytokinesis mechanisms. Science 305, 61-66.

[PDF]

Csankovszki, G., McDonel, P. and Meyer, B.J. (2004) Recruitment and Spreading of the C. elegans Dosage Compensation Complex along X Chromosomes. Science

303, 1182-1185. [PDF]

Chan, R.C., Severson, A.F., Meyer, B.J. (2004) Condensin Restructures Chromosomes in preparation for Meiotic Divisions. J. Cell Biology 167, 613-625. [PDF]

Yonker, S.A. and Meyer, B.J. (2003) Recruitment of C. elegans Dosage Compensation Proteins for Gene-Specific Versus Chromosome-Wide

Repression. Development 130, 6519-6532. [PDF]

Chan, R., Chan, A., Jeon, M., Wu, T., Pasqualone, D., Rougvie, A., Meyer, B. (2003) Chromosome cohesion is regulated by C. elegans TIM-1, a paralog of the clock

protein TIMELESS. Nature 423, 1002-1009. [PDF]

Luz, J.G., Hassig, C.A., Pickle, C., Godzik, A., Meyer, B.J., Wilson, I.A. (2003) XOL-1, Primary Determinant of Sexual Fate in C. elegans Is a GHMP Kinase Family Member

and a Structural Prototype for a New Class of Developmental Regulators. Genes Dev. 17, 977-990. [PDF]

Chu, D.S., Dawes, H.E., Lieb, J.D., Chan, R.C., Kuo, A.F., and Meyer B.J. (2002) A Molecular Link between Gene-Specific and Chromosome-Wide Transcriptional

Repression. Genes Dev. 16, 796-805. [PDF]

Hagstrom, K., Holmes, V., Cozzarelli, N., and Meyer, B.J. (2002) C. elegans Condensin Promotes Mitotic Chromosome Architecture, Centromere Organization, and

Sister Chromatid Segregation during Mitosis and Meiosis. Genes Dev. 16, 729-742. [PDF]

Howe, M., McDonald, K., Albertson, D., and Meyer, B.J. (2001) HIM-10 is required for kinetochore structure and function on C. elegans holocentric chromosomes. J.

Cell Biol. 153, 1227-1238. [PDF]

Lieb, J.D., Oritz de Solorzano, C., Rodriguez, E.G., Jones, A., Angelo, M. Lockett, S. and Meyer, B.J. (2000) The C. elegans Dosage Compensation Machinery is Recruited

to X-Chromosome DNA Attached to an Autosome. Genetics 156, 1603-1621. [PDF]

Meyer BJ. Mechanisms of sex determination and X-chromosome dosage compensation. Genetics, Volume 220, Issue 2,

February 2022, iyab197, doi.org/10.1093/genetics/iyab197. [PDF]

Ghosh RP, Meyer BJ. Spatial Organization of Chromatin: Emergence of Chromatin Structure During Development. Annu Rev

Cell Dev Biol. 2021 Jul 6. doi: 10.1146/annurev-cellbio-032321-035734. Epub ahead of print. PMID: 34228506. [PDF]

Krassovsky K, Ghosh RP, Meyer BJ. Genome-wide profiling reveals functional interplay of DNA sequence composition,

transcriptional activity, and nucleosome positioning in driving DNA supercoiling and helix destabilization in C. elegans.

Genome Res. 2021 Jun 24;31(7):1187–202. doi: 10.1101/gr.270082.120. Epub ahead of print. PMID: 34168009; PMCID:

PMC8256864. [PDF]

Farboud, B., Novak, C.S., Nicoll, M., Quiogue, A., Meyer, B.J. (2020). Dose-dependent action of the RNA binding protein FOX-1

to relay X-Chromosome number and determine C. elegans sex. eLife 2020;9:e62963. doi: 10.7554/eLife.62963. [PDF]

Bian, Q., Anderson, E.A., Yang, Q., Meyer, B.J. (2020). Histone H3K9 methylation promotes formation of genome

compartments in Caenorhabditis elegans via chromosome compaction and perinuclear anchoring. PNAS 117 (21)

11459-11470. doi.org/10.1073/pnas.2002068117. [PDF]

Anderson, E.A., Frankino, P.A., Higuchi-Sanabria, R., Yang, Q., Bian, Q., Podshivalova, K., Shin, A., Kenyon, C., Dillin, A., Meyer,

B.J. (2019). X Chromosome Domain Architecture Regulates Caenorhabditis elegans Lifespan but Not Dosage Compensation.

Developmental Cell (Epub 5 September 2019). [PDF]

Farboud, B., Severson, A.F., Meyer, B.J. (2019). Strategies for Efficient Genome Editing Using CRISPR-Cas9. Genetics 211;

431-457. doi: doi.org/10.1534/genetics.118.301775. [PDF]

Yin, D., Schwarz, E.M., Thomas, C.G., Felde, R.L., Korf, I.F., Cutter, A.D., Schartner, C.M., Ralston, E.J., Meyer, B.J., Haag, E.S.

(2018). Rapid Genome Shrinkage in a Self-Fertile Nematode Reveals Sperm Competition Proteins. Science 359: 55-61. DOI:

10.1126/science.aao0827 PMID: 29302007 PMCID: PMC5789457 [PDF]

Bian, Q., Anderson, E.C., Brejc, K., Meyer, B.J. (2018). Dynamic Control of Chromosome Topology and Gene Expression by a

Chromatin Modification. Cold Spring Harb Symp Quant Biol. pii: 034439. doi: 10.1101/sqb.2017.82.034439. [Epub ahead of

print] [PDF]

Meyer, B.J. (2018). Sex and death: from cell fate specification to dynamic control of X-chromosome structure and gene

expression. Molecular Biology of the Cell 29; 2603-2799. doi.org/10.1091/mbc.E18-06-0397. 1 November 2018. [PDF]

Meyer, B.J. (2018). On Sex and Death. Bulletin of the American Academy of Arts & Sciences. Summer 2018. [PDF]

Brejc, K., Bian, Q., Uzawa, S., Wheeler, B.J., Anderson, E.C., King, D.S., Kranzusch, P.J., Preston, C.G., Meyer B.J. (2017) Dynamic

Control of X Chromosome Conformation and Repression by a Histone H4K20 Demethylase. Cell, 2017 Sep

21;171(1):85-102.e23. doi: 10.1016/j.cell.2017.07.041. Epub 2017 Aug 31. PubMed PMID: 28867287. [PDF]

Wheeler BS, Anderson E, Frøkjær-Jensen C, Bian Q, Jorgensen E, Meyer BJ. (2016) Chromosome-wide mechanisms to

decouple gene expression from gene dose during sex-chromosome evolution. eLife, 2016 August 30;5 [PDF]

Crane, E., Bian, Q., McCord, R.P., Lajoie, B.R., Wheeler, B. S., Ralston, E.J., Uzawa, S., Dekker, J., Meyer, B.J. (2015)

Condensin-driven remodelling of X chromosome topology during dosage compensation. Nature, 1 June 2015

doi:10.1038/nature14450 [PDF]

Farboud, B., Meyer, B.J. (2015) Dramatic Enhancement of Genome Editing by CRISPR/Cas9 Through Improved Guide RNA

Design. Genetics, February 18, 2015 genetics.115.175166 [PDF]

Severson, A., Meyer, B.J. (2014) Divergent kleisin subunits of cohesin specify mechanisms to tether and release meiotic

chromosomes. eLife 2014;10.7554/eLife.03467 [PDF]

Libuda, D., Uzawa, S., Meyer, B.J., Villeneuve, A. (2013) Meiotic chromosome structures constrain and respond to designation

of crossover sites.

Nature 502, 703-706 (31 October 2013) [PDF]

Maxwell, C., Kruesi, W.S.., Core, L., Kurhanewicz, N., Waters, C., Lewarch, C., Antoshechkin, A., Lis, J., Meyer, B.J., Baugh, L.R..

(2014) Pol II Docking and Pausing at Growth and Stress Genes in C. elegans. Cell Reports Volume 6, Issue 3, p455-466, 13

February 2014 [PDF]

Pferdehirt, R.R., Meyer, B.J. (2013) SUMOylation is essential for sex-specific assembly and function of the Caenorhabditis

elegans dosage compensation complex on X chromosomes. PNAS 2013; doi:10.1073/pnas.1315793110 [PDF]

Lo, T.W., Pickle, C.S., Lin, S., Ralston, E.J., Gurling, M., Schartner, C.M., Bian, Q., Doudna, J.A., Meyer, B.J. (2013) Precise and

Heritable Genome Editing in Evolutionarily Diverse Nematodes Using TALENs and CRISPR/Cas9 to Engineer Insertions and

Deletions. Genetics 195; 331-348. [PDF]

Kruesi, W.S., Core, L.J., Waters, C.T., Lis, J.T., Meyer, B.J. (2013) Condensin controls recruitment of RNA polymerase II to

achieve nematode X-chromosome dosage compensation. eLife 2013; 2:e00808. [PDF]

Farboud, B., Nix, P., Jow, M.M., Gladden, J.M., Meyer, B.J. (2013) Molecular antagonism between X-chromosome and

autosome signals determines nematode sex. Genes & Development 27, 1159-1178. [PDF] [Supp.PDF]

Wood AJ*, Lo TW*, Zeitler B*, Pickle CS, Ralston EJ, Lee AH, Amora R, Miller JC, Leung E, Meng X, Zhang L, Rebar EJ, Gregory

PD, Urnov FD, Meyer BJ. (2011) Targeted genome editing across species using ZFNs and TALENs. Science 333, 307. *These

authors contributed equally to this work. [PDF] [Supp.PDF]

Pferdehirt, R. R., Kruesi, W. S., Meyer, B. J. (2011) An MLL/COMPASS Subunit Functions in the C. elegans Dosage

Compensation Complex to Target X Chromosomes for Transcriptional Regulation of Gene Expression. Genes & Development

25, 499-515. [PDF] [Supp.PDF]

Meyer, B. J. (2010) Targeting X chromosomes for repression. Current Opinion in Genetics & Development 20, 179-189. [PDF]

Wood, A. J., Severson, A. F., Meyer, B. J. (2010) Condensin and Cohesin Complexity: the Expanding Repertoire of Functions.

Nat. Rev. Genet. 11, 391-404. [PDF]

Youds, J. L., Mets, D. G., Mcllwraith, M. J., Martin, J. S., Ward, J. D., O'Neil, N. J., Rose, A. M., West, S. C., Meyer, B. J., Boulton, S. J.

(2010) RTEL-1 Enforces Meiotic Crossover Interference and Homeostasis. Science 327, 1254-1258. [PDF]

Mets, D. G., Meyer, B. J. (2009) A Condensin Complex Regulates DSB Distribution and thus Crossover Frequency by

Controlling Chromosome Structure. Cell 139, 73-86. [PDF] [Supp.PDF]

Severson, A.F., Ling, L., van Zuylen, V., Meyer, B.J. (2009) The axial element protein HTP-3 promotes cohesin loading and

meiotic axis assembly in C. elegans to implement the meiotic program of chromosome segregation. Genes & Development

23 (15), 1763-1778. [PDF] [Supp.PDF]

Jans, J. Gladden, J. M., Ralston, E. J., Pickle, C. S., Michel, A. H., Pferdehirt, R. R., Eisen, M. B., Meyer, B. J. (2009) A

condensin-like dosage compensation complex acts at a distance to control expression throughout the genome. Genes &

Development 23 (5), 602-618. [PDF] [Supp.PDF]

Csankovszki, G., Collette, K., Spahl, K., Carey, J., Snyder, M., Petty, E., Patel, U., Tabuchi, T., Liu, H., McLeod, I., Thompson, J.,

Sarkesik, A., Yates, J., Meyer, B.J., Hagstrom, K. (2009) Three distinct condensin complexes control C. elegans chromosome

dynamics. Current Biology 19 (1), 9-19. [PDF] [Supp.PDF]

Reiner, D.J., Ailion, M., Thomas, J.H., Meyer, B.J. (2008) C. elegans anaplastic lymphoma kinase ortholog SCD-2 controls dauer

formation by modulating TGF-beta signaling. Current Biology 18(15), 1101-9. [PDF] [Supp.PDF]

Tsai, C.J., Mets, D.G., Albrecht, M.R., Nix, P., Chan, A., Meyer, B.J. (2008) Meiotic crossover number and distribution are

regulated by a dosage compensation protein that resembles a condensin subunit. Genes & Development 22, 194-211. [PDF]

[Supp.PDF]

Gladden, J.M., Meyer, B.J. (2007) A ONECUT Homeodomain Protein Communicates X Chromosome Dose to Specify

Caenorhabditis elegans Sexual Fate by Repressing a Sex Switch Gene. Genetics 177 (3), 1621-1637. [PDF]

Gladden, J.M., Farboud, B., Meyer, B.J. (2007) Revisiting the X:A Signal That Specifies Caenorhabditis elegans Sexual Fate.

Genetics 177 (3), 1639-1654. [PDF]

McDonel, P.E., Jans, J., Peterson, B.K., Meyer, B.J. (2006) Clustered DNA motifs mark X chromosomes for repression by a

dosage compensation complex. Nature 444, 614-618. [PDF]

Chu, D.S., Liu, H., Nix, P., Wu, T.F., Ralston, E.J., Yates, J.R., Meyer, B.J. (2006) Sperm chromatin proteomics identifies

evolutionarily conserved fertility factors. Nature 443, 101-105. [PDF]

Powell, J.R., Jow, M.M., Meyer, B.J. (2005) The T-box transcription factor SEA-1 is an autosomal element of the X:A signal that

determines C. elegans sex. Dev. Cell 9 (3), 339-349. [PDF]

Meyer, B. J. X-Chromosome dosage compensation (June 25, 2005), WormBook, ed. The C. elegans Research Community,

WormBook, doi/10.1895/wormbook.1.8.1, http://www.wormbook.org. [PDF]

Skop, A., Liu, H., Yates, J., Meyer, B., Heald, R. (2004) Dissection of the mammalian midbody proteome reveals conserved

cytokinesis mechanisms. Science 305, 61-66. [PDF]

Csankovszki, G., McDonel, P. and Meyer, B.J. (2004) Recruitment and Spreading of the C. elegans Dosage Compensation

Complex along X Chromosomes. Science 303, 1182-1185. [PDF]

Chan, R.C., Severson, A.F., Meyer, B.J. (2004) Condensin Restructures Chromosomes in preparation for Meiotic Divisions. J.

Cell Biology 167, 613-625. [PDF]

Yonker, S.A. and Meyer, B.J. (2003) Recruitment of C. elegans Dosage Compensation Proteins for Gene-Specific Versus

Chromosome-Wide

Repression. Development 130, 6519-6532. [PDF]

Chan, R., Chan, A., Jeon, M., Wu, T., Pasqualone, D., Rougvie, A., Meyer, B. (2003) Chromosome cohesion is regulated by C.

elegans TIM-1, a paralog of the clock protein TIMELESS. Nature 423, 1002-1009. [PDF]

Luz, J.G., Hassig, C.A., Pickle, C., Godzik, A., Meyer, B.J., Wilson, I.A. (2003) XOL-1, Primary Determinant of Sexual Fate in C.

elegans Is a GHMP Kinase Family Member and a Structural Prototype for a New Class of Developmental Regulators. Genes

Dev. 17, 977-990. [PDF]

Chu, D.S., Dawes, H.E., Lieb, J.D., Chan, R.C., Kuo, A.F., and Meyer B.J. (2002) A Molecular Link between Gene-Specific and

Chromosome-Wide Transcriptional Repression. Genes Dev. 16, 796-805. [PDF]

Hagstrom, K., Holmes, V., Cozzarelli, N., and Meyer, B.J. (2002) C. elegans Condensin Promotes Mitotic Chromosome

Architecture, Centromere Organization, and Sister Chromatid Segregation during Mitosis and Meiosis. Genes Dev. 16,

729-742. [PDF]

Howe, M., McDonald, K., Albertson, D., and Meyer, B.J. (2001) HIM-10 is required for kinetochore structure and function on C.

elegans holocentric chromosomes. J. Cell Biol. 153, 1227-1238. [PDF]

Lieb, J.D., Oritz de Solorzano, C., Rodriguez, E.G., Jones, A., Angelo, M. Lockett, S. and Meyer, B.J. (2000) The C. elegans

Dosage Compensation Machinery is Recruited to X-Chromosome DNA Attached to an Autosome. Genetics 156, 1603-1621.

[PDF]

Meyer BJ. Mechanisms of sex determination

and X-chromosome dosage compensation.

Genetics, Volume 220, Issue 2, February 2022,

iyab197, doi.org/10.1093/genetics/iyab197.

[PDF]

Ghosh RP, Meyer BJ. Spatial Organization of

Chromatin: Emergence of Chromatin

Structure During Development. Annu Rev Cell

Dev Biol. 2021 Jul 6. doi:

10.1146/annurev-cellbio-032321-035734. Epub

ahead of print. PMID: 34228506. [PDF]

Krassovsky K, Ghosh RP, Meyer BJ.

Genome-wide profiling reveals functional

interplay of DNA sequence composition,

transcriptional activity, and nucleosome

positioning in driving DNA supercoiling and

helix destabilization in C. elegans. Genome Res.

2021 Jun 24;31(7):1187–202. doi:

10.1101/gr.270082.120. Epub ahead of print.

PMID: 34168009; PMCID: PMC8256864. [PDF]

Farboud, B., Novak, C.S., Nicoll, M., Quiogue,

A., Meyer, B.J. (2020). Dose-dependent action

of the RNA binding protein FOX-1 to relay

X-Chromosome number and determine C.

elegans sex. eLife 2020;9:e62963. doi:

10.7554/eLife.62963. [PDF]

Bian, Q., Anderson, E.A., Yang, Q., Meyer, B.J.

(2020). Histone H3K9 methylation promotes

formation of genome compartments in

Caenorhabditis elegans via chromosome

compaction and perinuclear anchoring. PNAS

117 (21) 11459-11470.

doi.org/10.1073/pnas.2002068117. [PDF]

Anderson, E.A., Frankino, P.A.,

Higuchi-Sanabria, R., Yang, Q., Bian, Q.,

Podshivalova, K., Shin, A., Kenyon, C., Dillin, A.,

Meyer, B.J. (2019). X Chromosome Domain

Architecture Regulates Caenorhabditis elegans

Lifespan but Not Dosage Compensation.

Developmental Cell (Epub 5 September 2019).

[PDF]

Farboud, B., Severson, A.F., Meyer, B.J. (2019).

Strategies for Efficient Genome Editing Using

CRISPR-Cas9. Genetics 211; 431-457. doi:

doi.org/10.1534/genetics.118.301775. [PDF]

Yin, D., Schwarz, E.M., Thomas, C.G., Felde,

R.L., Korf, I.F., Cutter, A.D., Schartner, C.M.,

Ralston, E.J., Meyer, B.J., Haag, E.S. (2018).

Rapid Genome Shrinkage in a Self-Fertile

Nematode Reveals Sperm Competition

Proteins. Science 359: 55-61. DOI:

10.1126/science.aao0827 PMID: 29302007

PMCID: PMC5789457 [PDF]

Bian, Q., Anderson, E.C., Brejc, K., Meyer, B.J.

(2018). Dynamic Control of Chromosome

Topology and Gene Expression by a

Chromatin Modification. Cold Spring Harb

Symp Quant Biol. pii: 034439. doi:

10.1101/sqb.2017.82.034439. [Epub ahead of

print] [PDF]

Meyer, B.J. (2018). Sex and death: from cell

fate specification to dynamic control of

X-chromosome structure and gene

expression. Molecular Biology of the Cell 29;

2603-2799. doi.org/10.1091/mbc.E18-06-0397.

1 November 2018. [PDF]

Meyer, B.J. (2018). On Sex and Death. Bulletin

of the American Academy of Arts & Sciences.

Summer 2018. [PDF]

Brejc, K., Bian, Q., Uzawa, S., Wheeler, B.J.,

Anderson, E.C., King, D.S., Kranzusch, P.J.,

Preston, C.G., Meyer B.J. (2017) Dynamic

Control of X Chromosome Conformation and

Repression by a Histone H4K20 Demethylase.

Cell, 2017 Sep 21;171(1):85-102.e23. doi:

10.1016/j.cell.2017.07.041. Epub 2017 Aug 31.

PubMed PMID: 28867287. [PDF]

Wheeler BS, Anderson E, Frøkjær-Jensen C,

Bian Q, Jorgensen E, Meyer BJ. (2016)

Chromosome-wide mechanisms to decouple

gene expression from gene dose during

sex-chromosome evolution. eLife, 2016 August

30;5 [PDF]

Crane, E., Bian, Q., McCord, R.P., Lajoie, B.R.,

Wheeler, B. S., Ralston, E.J., Uzawa, S., Dekker,

J., Meyer, B.J. (2015) Condensin-driven

remodelling of X chromosome topology

during dosage compensation. Nature, 1 June

2015 doi:10.1038/nature14450 [PDF]

Farboud, B., Meyer, B.J. (2015) Dramatic

Enhancement of Genome Editing by

CRISPR/Cas9 Through Improved Guide RNA

Design. Genetics, February 18, 2015

genetics.115.175166 [PDF]

Severson, A., Meyer, B.J. (2014) Divergent

kleisin subunits of cohesin specify

mechanisms to tether and release meiotic

chromosomes. eLife 2014;10.7554/eLife.03467

[PDF]

Libuda, D., Uzawa, S., Meyer, B.J., Villeneuve, A.

(2013) Meiotic chromosome structures

constrain and respond to designation of

crossover sites.

Nature 502, 703-706 (31 October 2013) [PDF]

Maxwell, C., Kruesi, W.S.., Core, L.,

Kurhanewicz, N., Waters, C., Lewarch, C.,

Antoshechkin, A., Lis, J., Meyer, B.J., Baugh,

L.R.. (2014) Pol II Docking and Pausing at

Growth and Stress Genes in C. elegans. Cell

Reports Volume 6, Issue 3, p455-466, 13

February 2014 [PDF]

Pferdehirt, R.R., Meyer, B.J. (2013)

SUMOylation is essential for sex-specific

assembly and function of the Caenorhabditis

elegans dosage compensation complex on X

chromosomes. PNAS 2013;

doi:10.1073/pnas.1315793110 [PDF]

Lo, T.W., Pickle, C.S., Lin, S., Ralston, E.J.,

Gurling, M., Schartner, C.M., Bian, Q., Doudna,

J.A., Meyer, B.J. (2013) Precise and Heritable

Genome Editing in Evolutionarily Diverse

Nematodes Using TALENs and CRISPR/Cas9 to

Engineer Insertions and Deletions. Genetics

195; 331-348. [PDF]

Kruesi, W.S., Core, L.J., Waters, C.T., Lis, J.T.,

Meyer, B.J. (2013) Condensin controls

recruitment of RNA polymerase II to achieve

nematode X-chromosome dosage

compensation. eLife 2013; 2:e00808. [PDF]

Farboud, B., Nix, P., Jow, M.M., Gladden, J.M.,

Meyer, B.J. (2013) Molecular antagonism

between X-chromosome and autosome

signals determines nematode sex. Genes &

Development 27, 1159-1178. [PDF] [Supp.PDF]

Wood AJ*, Lo TW*, Zeitler B*, Pickle CS,

Ralston EJ, Lee AH, Amora R, Miller JC, Leung

E, Meng X, Zhang L, Rebar EJ, Gregory PD,

Urnov FD, Meyer BJ. (2011) Targeted genome

editing across species using ZFNs and TALENs.

Science 333, 307. *These authors contributed

equally to this work. [PDF] [Supp.PDF]

Pferdehirt, R. R., Kruesi, W. S., Meyer, B. J.

(2011) An MLL/COMPASS Subunit Functions in

the C. elegans Dosage Compensation

Complex to Target X Chromosomes for

Transcriptional Regulation of Gene

Expression. Genes & Development 25, 499-515.

[PDF] [Supp.PDF]

Meyer, B. J. (2010) Targeting X chromosomes

for repression. Current Opinion in Genetics &

Development 20, 179-189. [PDF]

Wood, A. J., Severson, A. F., Meyer, B. J. (2010)

Condensin and Cohesin Complexity: the

Expanding Repertoire of Functions. Nat. Rev.

Genet. 11, 391-404. [PDF]

Youds, J. L., Mets, D. G., Mcllwraith, M. J.,

Martin, J. S., Ward, J. D., O'Neil, N. J., Rose, A.

M., West, S. C., Meyer, B. J., Boulton, S. J. (2010)

RTEL-1 Enforces Meiotic Crossover

Interference and Homeostasis. Science 327,

1254-1258. [PDF]

Mets, D. G., Meyer, B. J. (2009) A Condensin

Complex Regulates DSB Distribution and thus

Crossover Frequency by Controlling

Chromosome Structure. Cell 139, 73-86. [PDF]

[Supp.PDF]

Severson, A.F., Ling, L., van Zuylen, V., Meyer,

B.J. (2009) The axial element protein HTP-3

promotes cohesin loading and meiotic axis

assembly in C. elegans to implement the

meiotic program of chromosome segregation.

Genes & Development 23 (15), 1763-1778. [PDF]

[Supp.PDF]

Jans, J. Gladden, J. M., Ralston, E. J., Pickle, C. S.,

Michel, A. H., Pferdehirt, R. R., Eisen, M. B.,

Meyer, B. J. (2009) A condensin-like dosage

compensation complex acts at a distance to

control expression throughout the genome.

Genes & Development 23 (5), 602-618. [PDF]

[Supp.PDF]

Csankovszki, G., Collette, K., Spahl, K., Carey, J.,

Snyder, M., Petty, E., Patel, U., Tabuchi, T., Liu,

H., McLeod, I., Thompson, J., Sarkesik, A.,

Yates, J., Meyer, B.J., Hagstrom, K. (2009) Three

distinct condensin complexes control C.

elegans chromosome dynamics. Current

Biology 19 (1), 9-19. [PDF] [Supp.PDF]

Reiner, D.J., Ailion, M., Thomas, J.H., Meyer, B.J.

(2008) C. elegans anaplastic lymphoma kinase

ortholog SCD-2 controls dauer formation by

modulating TGF-beta signaling. Current Biology

18(15), 1101-9. [PDF] [Supp.PDF]

Tsai, C.J., Mets, D.G., Albrecht, M.R., Nix, P.,

Chan, A., Meyer, B.J. (2008) Meiotic crossover

number and distribution are regulated by a

dosage compensation protein that resembles

a condensin subunit. Genes & Development 22,

194-211. [PDF] [Supp.PDF]

Gladden, J.M., Meyer, B.J. (2007) A ONECUT

Homeodomain Protein Communicates X

Chromosome Dose to Specify Caenorhabditis

elegans Sexual Fate by Repressing a Sex

Switch Gene. Genetics 177 (3), 1621-1637. [PDF]

Gladden, J.M., Farboud, B., Meyer, B.J. (2007)

Revisiting the X:A Signal That Specifies

Caenorhabditis elegans Sexual Fate. Genetics

177 (3), 1639-1654. [PDF]

McDonel, P.E., Jans, J., Peterson, B.K., Meyer,

B.J. (2006) Clustered DNA motifs mark X

chromosomes for repression by a dosage

compensation complex. Nature 444, 614-618.

[PDF]

Chu, D.S., Liu, H., Nix, P., Wu, T.F., Ralston, E.J.,

Yates, J.R., Meyer, B.J. (2006) Sperm chromatin

proteomics identifies evolutionarily conserved

fertility factors. Nature 443, 101-105. [PDF]

Powell, J.R., Jow, M.M., Meyer, B.J. (2005) The

T-box transcription factor SEA-1 is an

autosomal element of the X:A signal that

determines C. elegans sex. Dev. Cell 9 (3),

339-349. [PDF]

Meyer, B. J. X-Chromosome dosage

compensation (June 25, 2005), WormBook, ed.

The C. elegans Research Community,

WormBook, doi/10.1895/wormbook.1.8.1,

http://www.wormbook.org. [PDF]

Skop, A., Liu, H., Yates, J., Meyer, B., Heald, R.

(2004) Dissection of the mammalian midbody

proteome reveals conserved cytokinesis

mechanisms. Science 305, 61-66. [PDF]

Csankovszki, G., McDonel, P. and Meyer, B.J.

(2004) Recruitment and Spreading of the C.

elegans Dosage Compensation Complex along

X Chromosomes. Science 303, 1182-1185.

[PDF]

Chan, R.C., Severson, A.F., Meyer, B.J. (2004)

Condensin Restructures Chromosomes in

preparation for Meiotic Divisions. J. Cell Biology

167, 613-625. [PDF]

Yonker, S.A. and Meyer, B.J. (2003)

Recruitment of C. elegans Dosage

Compensation Proteins for Gene-Specific

Versus Chromosome-Wide

Repression. Development 130, 6519-6532.

[PDF]

Chan, R., Chan, A., Jeon, M., Wu, T.,

Pasqualone, D., Rougvie, A., Meyer, B. (2003)

Chromosome cohesion is regulated by C.

elegans TIM-1, a paralog of the clock protein

TIMELESS. Nature 423, 1002-1009. [PDF]

Luz, J.G., Hassig, C.A., Pickle, C., Godzik, A.,

Meyer, B.J., Wilson, I.A. (2003) XOL-1, Primary

Determinant of Sexual Fate in C. elegans Is a

GHMP Kinase Family Member and a Structural

Prototype for a New Class of Developmental

Regulators. Genes Dev. 17, 977-990. [PDF]

Chu, D.S., Dawes, H.E., Lieb, J.D., Chan, R.C.,

Kuo, A.F., and Meyer B.J. (2002) A Molecular

Link between Gene-Specific and

Chromosome-Wide Transcriptional

Repression. Genes Dev. 16, 796-805. [PDF]

Hagstrom, K., Holmes, V., Cozzarelli, N., and

Meyer, B.J. (2002) C. elegans Condensin

Promotes Mitotic Chromosome Architecture,

Centromere Organization, and Sister

Chromatid Segregation during Mitosis and

Meiosis. Genes Dev. 16, 729-742. [PDF]

Howe, M., McDonald, K., Albertson, D., and

Meyer, B.J. (2001) HIM-10 is required for

kinetochore structure and function on C.

elegans holocentric chromosomes. J. Cell Biol.

153, 1227-1238. [PDF]

Lieb, J.D., Oritz de Solorzano, C., Rodriguez,

E.G., Jones, A., Angelo, M. Lockett, S. and

Meyer, B.J. (2000) The C. elegans Dosage

Compensation Machinery is Recruited to

X-Chromosome DNA Attached to an

Autosome. Genetics 156, 1603-1621. [PDF]

Meyer BJ. Mechanisms of sex determination and X-chromosome dosage compensation.

Genetics, Volume 220, Issue 2, February 2022, iyab197, doi.org/10.1093/genetics/iyab197.

[PDF]

Ghosh RP, Meyer BJ. Spatial Organization of Chromatin: Emergence of Chromatin

Structure During Development. Annu Rev Cell Dev Biol. 2021 Jul 6. doi:

10.1146/annurev-cellbio-032321-035734. Epub ahead of print. PMID: 34228506. [PDF]

Krassovsky K, Ghosh RP, Meyer BJ. Genome-wide profiling reveals functional interplay of

DNA sequence composition, transcriptional activity, and nucleosome positioning in

driving DNA supercoiling and helix destabilization in C. elegans. Genome Res. 2021 Jun

24;31(7):1187–202. doi: 10.1101/gr.270082.120. Epub ahead of print. PMID: 34168009;

PMCID: PMC8256864. [PDF]

Farboud, B., Novak, C.S., Nicoll, M., Quiogue, A., Meyer, B.J. (2020). Dose-dependent

action of the RNA binding protein FOX-1 to relay X-Chromosome number and determine

C. elegans sex. eLife 2020;9:e62963. doi: 10.7554/eLife.62963. [PDF]

Bian, Q., Anderson, E.A., Yang, Q., Meyer, B.J. (2020). Histone H3K9 methylation promotes

formation of genome compartments in Caenorhabditis elegans via chromosome

compaction and perinuclear anchoring. PNAS 117 (21) 11459-11470.

doi.org/10.1073/pnas.2002068117. [PDF]

Anderson, E.A., Frankino, P.A., Higuchi-Sanabria, R., Yang, Q., Bian, Q., Podshivalova, K.,

Shin, A., Kenyon, C., Dillin, A., Meyer, B.J. (2019). X Chromosome Domain Architecture

Regulates Caenorhabditis elegans Lifespan but Not Dosage Compensation. Developmental

Cell (Epub 5 September 2019). [PDF]

Farboud, B., Severson, A.F., Meyer, B.J. (2019). Strategies for Efficient Genome Editing

Using CRISPR-Cas9. Genetics 211; 431-457. doi: doi.org/10.1534/genetics.118.301775.

[PDF]

Yin, D., Schwarz, E.M., Thomas, C.G., Felde, R.L., Korf, I.F., Cutter, A.D., Schartner, C.M.,

Ralston, E.J., Meyer, B.J., Haag, E.S. (2018). Rapid Genome Shrinkage in a Self-Fertile

Nematode Reveals Sperm Competition Proteins. Science 359: 55-61. DOI:

10.1126/science.aao0827 PMID: 29302007 PMCID: PMC5789457 [PDF]

Bian, Q., Anderson, E.C., Brejc, K., Meyer, B.J. (2018). Dynamic Control of Chromosome

Topology and Gene Expression by a Chromatin Modification. Cold Spring Harb Symp

Quant Biol. pii: 034439. doi: 10.1101/sqb.2017.82.034439. [Epub ahead of print] [PDF]

Meyer, B.J. (2018). Sex and death: from cell fate specification to dynamic control of

X-chromosome structure and gene expression. Molecular Biology of the Cell 29;

2603-2799. doi.org/10.1091/mbc.E18-06-0397. 1 November 2018. [PDF]

Meyer, B.J. (2018). On Sex and Death. Bulletin of the American Academy of Arts & Sciences.

Summer 2018. [PDF]

Brejc, K., Bian, Q., Uzawa, S., Wheeler, B.J., Anderson, E.C., King, D.S., Kranzusch, P.J.,

Preston, C.G., Meyer B.J. (2017) Dynamic Control of X Chromosome Conformation and

Repression by a Histone H4K20 Demethylase. Cell, 2017 Sep 21;171(1):85-102.e23. doi:

10.1016/j.cell.2017.07.041. Epub 2017 Aug 31. PubMed PMID: 28867287. [PDF]

Wheeler BS, Anderson E, Frøkjær-Jensen C, Bian Q, Jorgensen E, Meyer BJ. (2016)

Chromosome-wide mechanisms to decouple gene expression from gene dose during

sex-chromosome evolution. eLife, 2016 August 30;5 [PDF]

Crane, E., Bian, Q., McCord, R.P., Lajoie, B.R., Wheeler, B. S., Ralston, E.J., Uzawa, S.,

Dekker, J., Meyer, B.J. (2015) Condensin-driven remodelling of X chromosome topology

during dosage compensation. Nature, 1 June 2015 doi:10.1038/nature14450 [PDF]

Farboud, B., Meyer, B.J. (2015) Dramatic Enhancement of Genome Editing by CRISPR/Cas9

Through Improved Guide RNA Design. Genetics, February 18, 2015 genetics.115.175166

[PDF]

Severson, A., Meyer, B.J. (2014) Divergent kleisin subunits of cohesin specify mechanisms

to tether and release meiotic chromosomes. eLife 2014;10.7554/eLife.03467 [PDF]

Libuda, D., Uzawa, S., Meyer, B.J., Villeneuve, A. (2013) Meiotic chromosome structures

constrain and respond to designation of crossover sites.

Nature 502, 703-706 (31 October 2013) [PDF]

Maxwell, C., Kruesi, W.S.., Core, L., Kurhanewicz, N., Waters, C., Lewarch, C., Antoshechkin,

A., Lis, J., Meyer, B.J., Baugh, L.R.. (2014) Pol II Docking and Pausing at Growth and Stress

Genes in C. elegans. Cell Reports Volume 6, Issue 3, p455-466, 13 February 2014 [PDF]

Pferdehirt, R.R., Meyer, B.J. (2013) SUMOylation is essential for sex-specific assembly and

function of the Caenorhabditis elegans dosage compensation complex on X

chromosomes. PNAS 2013; doi:10.1073/pnas.1315793110 [PDF]

Lo, T.W., Pickle, C.S., Lin, S., Ralston, E.J., Gurling, M., Schartner, C.M., Bian, Q., Doudna,

J.A., Meyer, B.J. (2013) Precise and Heritable Genome Editing in Evolutionarily Diverse

Nematodes Using TALENs and CRISPR/Cas9 to Engineer Insertions and Deletions.

Genetics 195; 331-348. [PDF]

Kruesi, W.S., Core, L.J., Waters, C.T., Lis, J.T., Meyer, B.J. (2013) Condensin controls

recruitment of RNA polymerase II to achieve nematode X-chromosome dosage

compensation. eLife 2013; 2:e00808. [PDF]

Farboud, B., Nix, P., Jow, M.M., Gladden, J.M., Meyer, B.J. (2013) Molecular antagonism

between X-chromosome and autosome signals determines nematode sex. Genes &

Development 27, 1159-1178. [PDF] [Supp.PDF]

Wood AJ*, Lo TW*, Zeitler B*, Pickle CS, Ralston EJ, Lee AH, Amora R, Miller JC, Leung E,

Meng X, Zhang L, Rebar EJ, Gregory PD, Urnov FD, Meyer BJ. (2011) Targeted genome

editing across species using ZFNs and TALENs. Science 333, 307. *These authors

contributed equally to this work. [PDF] [Supp.PDF]

Pferdehirt, R. R., Kruesi, W. S., Meyer, B. J. (2011) An MLL/COMPASS Subunit Functions in

the C. elegans Dosage Compensation Complex to Target X Chromosomes for

Transcriptional Regulation of Gene Expression. Genes & Development 25, 499-515. [PDF]

[Supp.PDF]

Meyer, B. J. (2010) Targeting X chromosomes for repression. Current Opinion in Genetics &

Development 20, 179-189. [PDF]

Wood, A. J., Severson, A. F., Meyer, B. J. (2010) Condensin and Cohesin Complexity: the

Expanding Repertoire of Functions. Nat. Rev. Genet. 11, 391-404. [PDF]

Youds, J. L., Mets, D. G., Mcllwraith, M. J., Martin, J. S., Ward, J. D., O'Neil, N. J., Rose, A. M.,

West, S. C., Meyer, B. J., Boulton, S. J. (2010) RTEL-1 Enforces Meiotic Crossover

Interference and Homeostasis. Science 327, 1254-1258. [PDF]

Mets, D. G., Meyer, B. J. (2009) A Condensin Complex Regulates DSB Distribution and

thus Crossover Frequency by Controlling Chromosome Structure. Cell 139, 73-86. [PDF]

[Supp.PDF]

Severson, A.F., Ling, L., van Zuylen, V., Meyer, B.J. (2009) The axial element protein HTP-3

promotes cohesin loading and meiotic axis assembly in C. elegans to implement the

meiotic program of chromosome segregation. Genes & Development 23 (15), 1763-1778.

[PDF] [Supp.PDF]

Jans, J. Gladden, J. M., Ralston, E. J., Pickle, C. S., Michel, A. H., Pferdehirt, R. R., Eisen, M. B.,

Meyer, B. J. (2009) A condensin-like dosage compensation complex acts at a distance to

control expression throughout the genome. Genes & Development 23 (5), 602-618. [PDF]

[Supp.PDF]

Csankovszki, G., Collette, K., Spahl, K., Carey, J., Snyder, M., Petty, E., Patel, U., Tabuchi, T.,

Liu, H., McLeod, I., Thompson, J., Sarkesik, A., Yates, J., Meyer, B.J., Hagstrom, K. (2009)

Three distinct condensin complexes control C. elegans chromosome dynamics. Current

Biology 19 (1), 9-19. [PDF] [Supp.PDF]

Reiner, D.J., Ailion, M., Thomas, J.H., Meyer, B.J. (2008) C. elegans anaplastic lymphoma

kinase ortholog SCD-2 controls dauer formation by modulating TGF-beta signaling.

Current Biology 18(15), 1101-9. [PDF] [Supp.PDF]

Tsai, C.J., Mets, D.G., Albrecht, M.R., Nix, P., Chan, A., Meyer, B.J. (2008) Meiotic crossover

number and distribution are regulated by a dosage compensation protein that resembles

a condensin subunit. Genes & Development 22, 194-211. [PDF] [Supp.PDF]

Gladden, J.M., Meyer, B.J. (2007) A ONECUT Homeodomain Protein Communicates X

Chromosome Dose to Specify Caenorhabditis elegans Sexual Fate by Repressing a Sex

Switch Gene. Genetics 177 (3), 1621-1637. [PDF]

Gladden, J.M., Farboud, B., Meyer, B.J. (2007) Revisiting the X:A Signal That Specifies

Caenorhabditis elegans Sexual Fate. Genetics 177 (3), 1639-1654. [PDF]

McDonel, P.E., Jans, J., Peterson, B.K., Meyer, B.J. (2006) Clustered DNA motifs mark X

chromosomes for repression by a dosage compensation complex. Nature 444, 614-618.

[PDF]

Chu, D.S., Liu, H., Nix, P., Wu, T.F., Ralston, E.J., Yates, J.R., Meyer, B.J. (2006) Sperm

chromatin proteomics identifies evolutionarily conserved fertility factors. Nature 443,

101-105. [PDF]

Powell, J.R., Jow, M.M., Meyer, B.J. (2005) The T-box transcription factor SEA-1 is an

autosomal element of the X:A signal that determines C. elegans sex. Dev. Cell 9 (3),

339-349. [PDF]

Meyer, B. J. X-Chromosome dosage compensation (June 25, 2005), WormBook, ed. The C.

elegans Research Community, WormBook, doi/10.1895/wormbook.1.8.1,

http://www.wormbook.org. [PDF]

Skop, A., Liu, H., Yates, J., Meyer, B., Heald, R. (2004) Dissection of the mammalian

midbody proteome reveals conserved cytokinesis mechanisms. Science 305, 61-66. [PDF]

Csankovszki, G., McDonel, P. and Meyer, B.J. (2004) Recruitment and Spreading of the C.

elegans Dosage Compensation Complex along X Chromosomes. Science 303, 1182-1185.

[PDF]

Chan, R.C., Severson, A.F., Meyer, B.J. (2004) Condensin Restructures Chromosomes in

preparation for Meiotic Divisions. J. Cell Biology 167, 613-625. [PDF]

Yonker, S.A. and Meyer, B.J. (2003) Recruitment of C. elegans Dosage Compensation

Proteins for Gene-Specific Versus Chromosome-Wide

Repression. Development 130, 6519-6532. [PDF]

Chan, R., Chan, A., Jeon, M., Wu, T., Pasqualone, D., Rougvie, A., Meyer, B. (2003)

Chromosome cohesion is regulated by C. elegans TIM-1, a paralog of the clock protein

TIMELESS. Nature 423, 1002-1009. [PDF]

Luz, J.G., Hassig, C.A., Pickle, C., Godzik, A., Meyer, B.J., Wilson, I.A. (2003) XOL-1, Primary

Determinant of Sexual Fate in C. elegans Is a GHMP Kinase Family Member and a

Structural Prototype for a New Class of Developmental Regulators. Genes Dev. 17,

977-990. [PDF]

Chu, D.S., Dawes, H.E., Lieb, J.D., Chan, R.C., Kuo, A.F., and Meyer B.J. (2002) A Molecular

Link between Gene-Specific and Chromosome-Wide Transcriptional Repression. Genes

Dev. 16, 796-805. [PDF]

Hagstrom, K., Holmes, V., Cozzarelli, N., and Meyer, B.J. (2002) C. elegans Condensin

Promotes Mitotic Chromosome Architecture, Centromere Organization, and Sister

Chromatid Segregation during Mitosis and Meiosis. Genes Dev. 16, 729-742. [PDF]

Howe, M., McDonald, K., Albertson, D., and Meyer, B.J. (2001) HIM-10 is required for

kinetochore structure and function on C. elegans holocentric chromosomes. J. Cell Biol.

153, 1227-1238. [PDF]

Lieb, J.D., Oritz de Solorzano, C., Rodriguez, E.G., Jones, A., Angelo, M. Lockett, S. and

Meyer, B.J. (2000) The C. elegans Dosage Compensation Machinery is Recruited to

X-Chromosome DNA Attached to an Autosome. Genetics 156, 1603-1621. [PDF]