The Portnoy Lab | UNIVERSITY OF CALIFORNIA, BERKELEY

JEG3 cells infected with *Listeria monocytogenes* (green) and stained for LAMP1 (red), actin (teal), and DAPI (blue).
*Listeria monocytogenes* mutant trapped in multilamellar body in a bone marrow macrophage.
*Listeria monocytogenes* infection: Actin (green), *Listeria monocytogenes* (red), DAPI (blue).
JEG3 cells infected with *Listeria monocytogenes* (green) and stained for LAMP1 (red), DAPI (blue), and phalloidin (yellow).
*Listeria monocytogenes* infection.

Mar

02

2023

Rafael Rivera-Lugo, graduate student, is the recipient of the Harold M. Weintraub Graduate Student Award!

By Neil Fischer

https://www.fredhutch.org/en/news/releases/2023/03/fred-hutch-announ

May

10

2022

Article published in Elife

By Neil Fischer

Listeria monocytogenes requires cellular respiration for NAD+ regeneration and pathogenesis. Rivera-Lugo R, Deng D, Anaya-Sanchez A, Tejedor-Sanz S, Tang E, Reyes Ruiz VM, Smith HB, Titov DV, Sauer JD, Skaar EP, Ajo-Franklin CM, Portnoy DA, Light SH. Elife. 2022 Apr 5;11:e75424.

May

10

2022

Article published in Proc Natl Acad Sci USA

By Neil Fischer

RibU is an essential determinant of Listeria pathogenesis that mediates acquisition of FMN and FAD during intracellular growth. Rivera-Lugo R, Light, SH, Garelis NE, Portnoy DA. Proc Natl Acad Sci USA 2022 Mar 29;119(13).

Oct

13

2021

John Berude, graduate student, has written an excellent feature for UC Berkeley's QB3 site.

By Neil Fischer

Little bacteria in a big world: Making sense of microbial sensing.

Aug

18

2021

Article published in PLOS PATHOGENS

By Neil Fischer

Detoxification of methylglyoxal by the glyoxalase system is required for glutathione availability and virulence activation in Listeria monocytogenes. Anaya-Sanchez A, Feng Y, Berude JC, Portnoy DA.

Nov

16

2020

SPOTLIGHT of article in Infection & Immunity

By Neil Fischer

https://iai.asm.org/content/88/12/e00628-20

Nov

16

2020

Publication in Infection & Immunity

By Neil Fischer

Secretion of c-di-AMP by Listeria monocytogenes leads to a STING-dependent antibacterial response during enterocolitis. Louie A, Bhandula V, Portnoy DA. Infect Immun. 2020 Oct 5;IAI.00407-20. doi: 10.1128/IAI.00407-20. PMID: 33020211. (2020).

Sep

02

2020

PUBLICATION in MBIO

By Neil Fischer

(p)ppGpp and ci-di-AMP homeostasis is controlled by CbpB in Listeria monocytogenes. Peterson BN, Young MKM, Luo, S, Wang J, Whiteley AT, Woodward JJ, Tong L, Wang JD, Portnoy DA. mBio 2020 Aug 25;11(4):e01625-20. doi: 10.1128/mBio.01625-20. PMID: 32843560. (2020).

Aug

31

2020

Publication in PROC NATL ACAD SCI USA

By Neil Fischer

Secondary structure of the mRNA encoding listeriolysin O is essential to establish the replicative niche of L. monocytogenes. Peterson BN, Portman JL, Feng Y, Wang J, Portnoy DA. Proc Natl Acad Sci - U S A. (2020).

Jul

07

2020

Publication in PLoS PATHOG

By Neil Fischer

TLR2 and endosomal TLR-mediated secretion of IL-10 and immune suppression in response to phagosome-confined Listeria monocytogenes. Nguyen BN, Chavez-Arroyo A, Louie A, Cheng MI, Krasilnikov M, Portnoy DA. PLoS Pathog. 2020 Jul 7;16(7):e1008622. doi: 10.1371/journal.ppat.1008622. eCollection 2020 Jul. PMCID: PMC7340287. (2020).

Pages