Reversibly caged glutamate: a photochromic agonist of ionotropic glutamate receptors

Volgraf, M., Gorostiza, P., Szobota, S., Helix, M.R., Isacoff, E.Y., Trauner, D. 2007, Journal of the American Chemical Society

Abstract

The design, synthesis, and biological evaluation of a photochromic glutamate analogue is described. The molecule functions as a reversibly caged neurotransmitter and can be used to influence neural activity with light.