The unifying theme of research in our lab is "growth regulation".
Here are review articles that discuss different aspects of growth regulation:
Hariharan IK and Serras F (2017) Imaginal disc regeneration takes flight. Curr Opin Cell Biol 48:10. Link to PubMed
Hariharan IK (2015) Organ size control: Lessons from Drosophila. Dev Cell 10:265. Link to PubMed.
Hariharan IK, Wake DB, Wake MH (2015) Indeterminate growth: could it represent the ancestral condition? Cold Spring Harbor Perspect Biol doi: 10.1101/cshperspect.a019174 Link to PubMed.
Worley MI, Setiawan L, Hariharan IK (2012) Regeneration and transdetermination in Drosophila imaginal discs Annu Rev Genet 46:289. Link to PubMed.
1. Growth
What mechanisms enable organs reach an appropriate size and shape during their development?
Why do some animals never stop growing?
(To read about our work on Growth, click here)
2. Regeneration
Why are some organisms good at regeneration and others not?
Why do organisms become less capable of regeneration as they mature?
(To read about our work on Regeneration, click here)
3. Cell Competition
How can cells in an epithelium influence the survival and proliferation of their neighbors?
(To read about our work on Cell Competition, click here)
4. Metabolism, Fat Storage and Energy Homeostasis
(To read about our work on metabolism, click here)
