Publications

 

Gammaherpesviral gene expression and virion composition are broadly controlled by accelerated mRNA degradationAbernathy E, Clyde K, Yeasmin R, Krug LT, Burlingame A, Coscoy L, Glaunsinger B. PLoS Pathog. 2014 Jan;10(1):e1003882. PMID: 24453974 

A Role for Host Activation-Induced Cytidine Deaminase in Innate Immune Defense against KSHV. Bekerman E, Jeon D, Coscoy L. PLoS Pathog. 2013 Nov;9(11):e1003748

A Novel Peptide-Based SILAC Method to Identify the Posttranslational Modifications Provides Evidence for Unconventional Ubiquitination in the ER-Associated Degradation Pathway. Anania VG, Bustos DJ, Lill JR, Kirkpatrick DS, Coscoy L. Int J Proteomics. 2013;2013:857918. doi: 10.1155/2013/857918. PMID: 22048770

Virally-induced upregulation of heparan sulfate on B cells via the action of type I IFN. Jarousse N, Trujillo DL, Wilcox-Adelman S, Coscoy L. J Immunol. 2011 Dec 1;187(11):5540-7. PMID: 22048770

Expression of the RAE-1 family of stimulatory NK-cell ligands requires activation of the PI3K pathway during viral infection and transformation. Tokuyama M, Lorin C, Delebecque F, Jung H, Raulet DH, Coscoy L. PLoS Pathog. 2011 Sep;7(9):e1002265. PMID: 21966273

Global mRNA degradation during lytic gammaherpesvirus infection contributes to establishment of viral latency. Richner JM, Clyde K, Pezda AC, Cheng BY, Wang T, Kumar GR, Covarrubias S, Coscoy L, Glaunsinger B. PLoS Pathog. 2011 Jul;7(7):e1002150. PMID: 21811408

Suppression of TLR9 immunostimulatory motifs in the genome of a gammaherpesvirus. Pezda AC, Penn A, Barton GM, Coscoy L. J Immunol. 2011 Jul 15;187(2):887-96. PMID: 21666062 [PubMed - indexed for MEDLINE]

Fas-associated death domain (FADD) and the E3 ubiquitin-protein ligase TRIM21 interact to negatively regulate virus-induced interferon production. Young JA, Sermwittayawong D, Kim HJ, Nandu S, An N, Erdjument-Bromage H, Tempst P, Coscoy L, Winoto A. J Biol Chem. 2011 Feb 25;286(8):6521-31. PMID: 21183682

Palmitoylation of MIR2 is required for its function. Anania VG, Coscoy L. J Virol. 2011 Mar;85(5):2288-95. PMID: 21159884

Stress-regulated targeting of the NKG2D ligand Mult1 by a membrane-associated RING-CH family E3 ligase. Nice TJ, Deng W, Coscoy L, Raulet DH. J Immunol. 2010 Nov 1;185(9):5369-76. PMID: 20870941

The U24 protein from human herpesvirus 6 and 7 affects endocytic recycling. Sullivan BM, Coscoy L. J Virol. 2010 Feb;84(3):1265-75. PMID: 19923186

Posttranslational regulation of the NKG2D ligand Mult1 in response to cell stress. Nice TJ, Coscoy L, Raulet DH. J Exp Med. 2009 Feb 16;206(2):287-98. PMID: 19171762

Lack of heparan sulfate expression in B-cell lines: implications for Kaposi's sarcoma-associated herpesvirus and murine gammaherpesvirus 68 infections. Jarousse N, Chandran B, Coscoy L. J Virol. 2008 Dec;82(24):12591-7. PMID: 18842731

The specificities of Kaposi's sarcoma-associated herpesvirus-encoded E3 ubiquitin ligases are determined by the positions of lysine or cysteine residues within the intracytoplasmic domains of their targets. Cadwell K, Coscoy L. J Virol. 2008 Apr;82(8):4184-9. PMID: 18272573

Selection of mutant CHO clones resistant to murine gammaherpesvirus 68 infection. Jarousse N, Coscoy L. Virology. 2008 Apr 10;373(2):376-86. PMID: 18191980

DNA mismanagement leads to immune system oversight. Coscoy L, Raulet DH. Cell. 2007 Nov 30;131(5):836-8. PMID: 18045527

Downregulation of the T-cell receptor complex and impairment of T-cell activation by human herpesvirus 6 U24 protein. Sullivan BM, Coscoy L. J Virol. 2008 Jan;82(2):602-8. PMID: 17977973

Immune evasion by Kaposi's sarcoma-associated herpesvirus. Coscoy L. Nat Rev Immunol. 2007 May;7(5):391-401. PMID: 17457345

Ubiquitination on nonlysine residues by a viral E3 ubiquitin ligase. Cadwell K, Coscoy L. Science. 2005 Jul 1;309(5731):127-30. Jan 13;311(5758):177. PMID: 15994556