Week |
Lecture |
Date |
Topic |
|
Notes |
Readings |
1 |
1 |
8/27 |
Introduction; The Physical Nature of Genetic Information
(In printer format)
|
AD |
No Sections |
Week 1 Reading and Problems
|
2 |
8/29 |
Mendel's Laws
(In printer format) |
AD |
No Sections |
|
2 |
|
9/1 |
Labor Day Holiday |
|
Sections Begin |
|
3 |
9/3 |
Extensions to Mendel, Revised 9/5 |
SA |
|
Amacher Readings and Problems |
4 |
9/5 |
Chromosomes and Inheritance |
SA |
|
|
3 |
5 |
9/8 |
Pedigree Analysis |
SA |
QUIZ #1 THIS WEEK |
Pedigree Diagrams |
6 |
9/10 |
Linkage and Genetic Maps I
|
SA |
|
|
7 |
9/12 |
Linkage and Genetic Maps II |
SA |
|
|
4 |
8 |
9/15 |
Tetrad Analysis I |
SA |
|
|
9 |
9/17 |
Tetrad Analysis II, Gene Conversion |
SA |
|
|
10 |
9/19 |
Chromosomal Rearrangements I |
SA |
|
|
5 |
11 |
9/22 |
Chromosomal Rearrangements II |
SA |
QUIZ #2 THIS WEEK |
|
12 |
9/24 |
Changes in Chromosomal Number |
SA |
|
|
13 |
9/26 |
Review of Amacher Lectures |
SA |
|
|
6 |
14 |
9/29 |
Sex chromosomes, dosage compensation, and aneuploidy
(In printer format)
|
AD |
|
|
15 |
10/1 |
Where mutations come from (Ch. 7)
(In printer format) |
AD |
|
Chapter 7 Reading and Problems |
16 |
10/3 |
Linking genes to proteins, complementation tests (Ch. 7)
(In printer format)
|
AD |
|
Problem 26
(In printer format)
|
7 |
17 |
10/6 |
Gene expression; how mutations affect gene function (Ch. 8)
(In printer format)
|
AD |
MIDTERM ON 10/6 |
Chapter 8 Reading and Problems
|
18 |
10/8 |
Intro. to C. elegans, hermaphrodite genetics, and screens
(In printer format)
C. elegans Portrait |
AD |
|
C. elegans Readings and Problems
Answer Key REVISED 10/18 |
19 |
10/10 |
Apoptosis in C. elegans, gene mapping, and pathway analysis
(In printer format)
|
AD |
|
Lecture 9 Problem
Answer Key |
|
8 |
20 |
10/13 |
Genetic suppressors and enhancers I: informational suppressors
(In printer format) |
AD |
|
|
21 |
10/15 |
Suppressors and enhancers II: genetic pathways
(In printer format) |
AD |
|
Suppressor Readings and Problems
Answer Key
|
22 |
10/17 |
Discovery, mechanism, and application of RNAi
(In printer format) |
AD |
|
|
|
9 |
23 |
10/20 |
The cell cycle in yeast; temperature-sensitive mutations
(In printer format)
|
AD |
QUIZ #3 THIS WEEK |
Chapter 19 Reading and Problems |
24 |
10/22 |
Cancer genetics
(In printer format) |
AD |
|
|
25 |
10/24 |
Review |
AD |
|
Putting Genes Into Pathways |
|
10 |
26 |
10/27 |
Organelle Genetics |
SA |
|
|
27 |
10/29 |
Epigenetics: Imprinting |
SA |
|
|
|
10/31 |
Developmental Genetics: Zebrafish as a model system REVISED 11/02 |
SA |
|
Supplemental Reading 1
Supplemental Reading 2
Figure 1 (clearer)
Lecture 14 Problems
Solutions: Don't check answers until after you try the problems! |
|
11 |
29 |
11/3 |
Reverse genetics in the mouse |
SA |
MIDTERM ON 11/6 |
|
30 |
11/5 |
Cloning, libraries and sequencing REVISED AGAIN (II) 11/10 |
MS |
|
|
31 |
11/7 |
Human genome and Polymorphic markers REVISED AGAIN (IV) 11/12 |
MS |
|
|
12 |
32 |
11/10 |
Human genome and Polymorphic markers (see above) |
MS |
|
|
33 |
11/12 |
Positional cloning (see above) |
MS |
|
|
34 |
11/14 |
Genome wide association studies |
MS |
|
|
13 |
35 |
11/17 |
Population genetic variation |
MS |
QUIZ #4 THIS WEEK |
CA DNA Partial Match Policy |
36 |
11/19 |
Hardy-Weinberg |
MS |
|
|
37 |
11/21 |
Selection |
MS |
|
|
|
14 |
38 |
11/24 |
Genetic drift REVISED 12/02 |
MS |
|
|
39 |
11/26 |
Quantitative characters (see above) |
MS |
|
|
|
11/28 |
THANKSGIVING HOLIDAY |
|
|
|
|
15 |
40 |
12/1 |
Multigene families REVISED 12/02 |
|
QUIZ #5 THIS WEEK |
|
41 |
12/3 |
Neutral evolution REVISED 12/09 |
|
|
|
42 |
12/5 |
Evolutionary rates |
|
|
|
| 16 |
43 |
12/8 |
Primate and Human evolution |
|
|
|
44 |
12/10 |
Review |
|
|
|
|
|
12/19 |
FINAL, 8-11 am |
|
|
|
