Symposium Schedule
Saturday, March 21, 2015
8:45 a.m.-5:00 p.m
245 Li Ka Shing Center
8:45 Opening remarks by James Hurley
Session I Molecular and biochemical mechanisms of autophagy
(Chair, James Hurley)
9:00-9:40 Daniel Klionsky, University of Michigan
“The regulation and mechanism of autophagy”
9:40-10:20 Brenda Schulman, St. Jude Children's Research Hospital
"Mechanisms of ubiquitin-like protein conjugation"
10:20-11:00 Sascha Martens, Max F. Perutz Laboratories, University of Vienna, Austria
“Molecular mechanisms of selective autophagy"
11:00-11:20 Break (2nd floor lobby of LKS)
Session II Autophagy in neuronal homeostasis and neurodegeneration
(Chair, Roberto Zoncu)
11:20-12:00 Richard Youle, National Institutes of Health/NINDS
"How autophagy machinery is activated and recruited downstream of Parkin
ubiquitination of mitochondria"
12:00-12:40 Andrea Ballabio. Telethon Institute of Genetics and Medicine, Naples, Italy and
Baylor College of Medicine
"The lysosome as a signaling hub"
12:40-2:00 Lunch (not provided)
2:00-2:40 Erika Holzbaur, University of Pennsylvania
“Autophagy and mitophagy in neuronal homeostasis and neurodegeneration”
Session III Emerging physiological roles of autophagy
(Chair, Randy Schekman)
2:40-3:20 Emmanuelle Passegué, University of California, San Francisco
"Autophagy in hematopoietic stem cell function"
3:20-4:00 Craig Roy, Yale School of Medicine
"Microbial manipulation of host autophagy"
4:00-4:40 Alec Kimmelman, Dana Farber Cancer Institute and Harvard Medical School
”Autophagy, metabolism, and pancreatic cancer”
4:40 Closing remarks by Randy Schekman
Reception (2nd floor lobby of LKS)