Selected Publications

When peptides don’t make the final cut: Loss of ERAAP aminopeptidase disrupts the peptide repertoire displayed by MHC I. [G.E. Hammer, F. Gonzalez, M. Champsaur, D. Cado and N. Shastri (2005) Nature Immunology (In press)]

All the peptides that fit. The beginning, the middle, and the end of the MHC class I antigen processing pathway. [N. Shastri, S. Cardinaud, S. R. Schwab, T. Serwold and J. Kunisawa (2005) Immunological Reviews (In press)]

Unanticipated antigens: Translational initiation at CUG with a leucine. [S. R. Schwab, J. Shugart, T. Horng, S. Malarkannan, and N. Shastri (2004) PLoS Biology 2:e366]

The Group II chaperonin TriC protects antigenic intermediates from degradation in the MHC class I antigen processing pathway. [J. Kunisawa and N. Shastri (2003) Molecular Cell 12: 565-576]

MHC I molecules constitutively present cryptic translation products. [S. R. Schwab, K. Li, C. Kang and N. Shastri (2003) Science 301, 1367-1371]

Second class minors. Molecular identification of the autosomal H46 histocompatibility locus as a peptide presented by MHC class II molecules. [H. Sahara and N. Shastri (2003) J. Exp. Med.197, 375-385]

ERAAP customizes peptides for presentation by MHC class I molecules in the endoplasmic reticulum. [T. Serwold, F. Gonzalez, J. Kim, R. Jacob and N. Shastri (2002) Nature 419, 480-483]

Producing nature's gene-chips: The generation of peptides for display by MHC class I molecules. [N. Shastri, S. Schwab and T. Serwold (2002) Annual Reviews in Immunology, 20:463-493]

Differences that matter: Major cytotoxic T cell stimulating minor histocompatibility antigens. [S. Malarkannan, T. Horng, P. Eden, F. Gonzalez, P. Shih, N. Brouwenstijn, D. Roopenian and N. Shastri (2000) Immunity 13:333-344]