Here's the system in the presence of TEA, a blocker of potassium channels. With potassium channels blocked, membrane depolarization initiates opening of the sodium activation gate, and a bit later, closing of the sodium inactivation gate. Current flows inward when the activation gate opens, and that current is reduced when the inactivation gate closes.

 

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Basic Voltage Clamp Strategy

Clamp in the presence of TTX blocking Na Channels

Clamp in the presence of TEA blocking K Channels