A brief biography of Randy on the HHMI website.
News about Randy's 2013 Nobel Prize in Physiology/Medicine.
Photos from the Schekman Symposium held in August 2014.
Causing a stir in the scientific community, exosomes - a type of extracellular vesicle - still remain elusive in nature. Basic biochemical evidence is still needed to understand the key aspects of EV biology. One of the main functions of EVs is to transfer functional cargo that may alter the status of recipient cells. EVs may also play a strong role in cancer therapeutics. Thus, it is necessary to understand the mechanism through which EVs operate. My research goal is to better understand EV biology, by exploring the interactions between EVs and other cells. By developing and studying interactions between EVs and recipient cell surfaces, I aim to find pathways that can help deliver specific exosomally-packaged material to target cells.
I'm investigating the role of autophagy-related protein 8 (Atg8) homologues in autophagosome biogenesis.