Publications

A complete list of Hernan's publications can also be found in Google Scholar.

  • Books

    Physical Biology of the Cell, 2nd edition, Rob Phillips, Jane Kondev, Julie Theriot and Hernan G. Garcia, Garland Science, New York, (2013). Book website | Erratum

    Recipient of the 2013 The Society of Biology Award for an Outstanding Biology/Biosciences/Life Sciences Textbook for Undergraduates.

  • Articles

    Nathan BelliveauGriffin ChureChristina HueschenHernan GarciaJane KondevDaniel FisherJulie TheriotRob Phillips, Fundamental limits on the rate of bacterial growth, 

  • Jonathan LiuDonald HansenElizabeth EckYang Joon KimMeghan TurnerSimon Alamos and Hernan G. Garcia, Quantitative characterization of the eukaryotic transcription cycle using live imaging and statistical inference, 

  • Myron Child VIJack R. BatemanAmir JahangiriArmando ReimerNicholas C. LammersNica SabouniDiego VillamarinGrace C. McKenzie-SmithJustine E. JohnsonDaniel Jost, and Hernan G. Garcia, Live imaging and biophysical modeling support a button-based mechanism of somatic homolog pairing in Drosophila 

  • Nicholas C. Lammers, Yang Joon Kim,  Jiaxi Zhao and Hernan G. Garcia, A matter of time: Using dynamics and theory to uncover mechanisms of transcriptional bursting,  https://arxiv.org/abs/2008.09225 submitted to Quantitative Biology,8.20.2020. [PDF]

  • Simon AlamosArmando ReimerKrishna K. NiyogiHernan G. Garcia, Quantitative imaging of RNA polymerase II activity in plants reveals the single-cell basis of tissue-wide transcriptional dynamics

  • Matthew G. EasonAntonia T. PandelievaMarc M. MayerSafwat T. KhanHernan G. GarciaRoberto A. Chica Genetically-encoded fluorescent biosensor for rapid detection of protein expression  

    doi: https://doi.org/10.1101/2020.07.30.229633 [PDF]

  • Hernan Garcia, Augusto Berrocal, Yang Joon Kim, Gabriella Martini, and Jiaxi Zhao, Lighting up the central dogma for predictive developmental biologyCurrent Topics in Developmental Biology, 137,1-35 (2020). [PDF]

  • Elizabeth EckJonathan LiuMaryam Kazemzadeh-AtoufiSydney GhoreishiShelby A BlytheHernan Garcia. Quantitative dissection of transcription in development yields evidence for transcription factor-driven chromatin accessibility, 

  • Nicholas Lammers, Vahe Galstyan, Armando Reimer, Sean Medin, Chris Wiggins, & Hernan Garcia, (2020). Multimodal transcriptional control of pattern formation in embryonic development. Proceedings of the National Academy of Sciences, 117(2), 836–847. http://doi.org/10.1073/PNAS.1912500117. [PDF | SI]

  • Rob Phillips, Nathan M. Belliveau, Griffin Chure, Hernan G. Garcia, Manuel Razo-Mejia, and Clarissa Scholes: Figure 1 Theory Meets Figure 2 Experiments in the Study of Gene Expression, in Annual Review of Biophysics, vol.48, pp. 121-165 (May 2019).  [PDF]

  • Julia Falo-Sanjuan, Nicholas C. Lammers, Hernan G. Garcia, Sarah Bray: Enhancer priming enables fast and sustained transcriptional responses to Notch signalingDevelopmental Cell, 50: 411–435 (August 2019). [PDF]

  • Shigehiro YamadaPeter H. WhitneyShao-Kuei HuangElizabeth C. EckHernan G. GarciaChristine A. Rushlow: The Drosophila pioneer factor Zelda modulates the nuclear microenvironment of a Dorsal target enhancer to potentiate transcriptional output, in Current Biology, 29(8):1387-1401 (2019).

    doi: 10.1016/j.cub.2019.03.019   [PDF

  •  Nicholas Lammers, Vahe Galstyan, Armando Reimer, Sean Medin, Chris Wiggins, Hernan Garcia: Binary transcriptional control of pattern formation in development, PNAS (2019). [PDF | SI]

  • Augusto Berrocal, Nicholas Lammers, Hernan Garcia, Michael Eisen: Kinetic sculpting of the seven stripes of the Drosophila even-skipped gene, bioRxiv, 335901 (2018). doi: https://doi.org/10.1101/335901

  • Mustafa Mir, Armando Reimer, Michael Stadler, Astou Tangara, Anders S. Hansen, Dirk Hockemeyer, Michael Eisen, Hernan Garcia, Xavier Darzacq: Single Molecule Imaging in Live Embryos Using Lattice Light-Sheet Microscopy, in Nanoscale Imaging. Methods in Molecular Biology, vol.1814, pp. 541-559. Humana Press, New York (2018). [PDF]

  • Vincent Boudreau, James Hazel, Jake Sellinger, Pan Chen, Kathryn Manakova, Rochelle Radzyminski, Hernan Garcia, Jun Allard, Jesse Gatlin, Paul Maddox: Nucleo-cytoplasmic trafficking regulates nuclear surface area during nuclear organogenesis, bioRxiv 326140;  doi: https://doi.org/10.1101/326140 (2018) [PDF]

  • Hernan G. Garcia, Thomas Gregor: Live Imaging of mRNA Synthesis in Drosophila. In: Gaspar I. (eds) RNA Detection: Methods in Molecular Biology, vol 1649. Humana Press, New York, NY (2018). [PDF]

  • Jacques P. Bohtma, Matthew R. Norstad, Simon Alamos, Hernan G. Garcia: LlamaTags: A Versatile Tool to Image Transcription Factor Dynamics in Live Embryos. Cell 173:1 (2018). PDF | SI movies

  • Mustafa MirArmando ReimerJenna E. HainesXiao-Yong LiMichael StadlerHernan G. GarciaMichael E. Eisen and Xavier Darzacq: Dense Bicoid Hubs Accentuate Binding along the Morphogen Gradient

  • Hernan G. Garcia, Robert C Brewster and Rob Phillips: Using synthetic biology to make cells tomorrow’s test tubesIntegrative Biology 8:431 (2016). PDF

  • Mattias Rydenfelt, Hernan G. Garcia, Robert Sidney Cox III and Rob Phillips: The influence of promoter architectures and regulatory motifs on gene expression in Escherichia coli. PLOS One, 10(3): e0121935 (2014). PDF | SI Figures | SI Tables

  • Thomas Gregor, Hernan G. Garcia and Shawn C. Little: The embryo as a laboratory: quantifying transcription in DrosophilaTrends in Genetics 30:364 (2014). [pdf full text]

  • Jacques P. Bothma*, Hernan G. Garcia*, Emilia Esposito, Gavin Schlissel, Thomas Gregor and Michael Levine: Dynamic Regulation of Eve Stripe 2 Expression Reveals Transcriptional Bursts in Living Drosophila EmbryosPNAS 111(29):10598 (2014).

  • Hernan G. Garcia, Paul Grayson, Lin Han, Mandar Inamdar, Jane Kondev, Philip C. Nelson, Rob Phillips, Jonathan Widom and Paul A. Wiggins: Biological Consequences of Tightly Bent DNA: The Other Life of a Macromolecular Celebrity, Biopolymers 85(2):115-130 (2007). [pdf full text]

  • Lacramioara Bintu, Nicolas E. Buchler, Hernan G. Garcia, Ulrich Gerland, Terence Hwa, Jane Kondev, Thomas Kuhlman and Rob Phillips.Transcriptional Regulation by the Numbers 2: ApplicationsCurr. Opin. Genet. & Dev. 15(2):125-135 (2005). [PDF]

  • Lacramioara Bintu, Nicolas E. Buchler, Hernan G. Garcia, Ulrich Gerland, Terence Hwa, Jane Kondev, and Rob Phillips: Transcriptional Regulation by the Numbers 1: ModelsCurr. Opin. Genet. & Dev. 15(2):116-124 (2005). [PDF]