Phil Frankino

Ph.D. Candidate


I obtained my B.S. in Biochemistry from the State University of New York at Fredonia in the spring of 2016. My undergraduate research was focused on understanding the translational regulation of an important morphogen, Gurken, in Drosophila oogenesis. In the Dillin lab, I am interested in investigating the role of the cytoplasmic stress response in the context of aging and longevity in the model organism C. elegans, working with Ryo Higuchi-Sanabria. 



The Hyaluronidase, TMEM2, Promotes ER Homeostasis and Longevity Independent of the UPRER.  Schinzel RT, Higuchi-Sanabria R, Shalem O, Moehle EA, Webster BM, Joe L, Bar-Ziv R, Frankino PA, Durieux J, Pender C, Kelet N, Kumar SS, Savalia N, Chi H, Simic M, Nguyen NT, Dillin A.  Cell. 2019 Nov 27;179(6):1306-1318.  

X Chromosome Domain Architecture Regulates Caenorhabditis elegans Lifespan but Not Dosage Compensation.  Anderson EC, Frankino PA, Higuchi-Sanabria R, Yang Q, Bian Q, Podshivalova K, Shin A, Kenyon C, Dillin A, Meyer BJ.  Dev Cell. 2019 Oct 21;51(2):192-207.  
Intercellular communication is required for trap formation in the nematode-trapping fungus Duddingtonia flagrans.  Youssar L, Wernet V, Hensel N, Yu X,  Hildebrand HG, Schreckenberger B, Kriegler M, Hetzer B, Frankino P, Dillin A, Fischer R.  PLoS Genet. 2019 Mar 27;15(3)
Evolutionary Comeuppance: Mitochondrial Stress Awakens the Remnants of Ancient Bacterial Warfare.  Frankino PA, Moehle EA, Dillin A.  Cell Metab. 2019 May 7;29(5):1015-1017.