Life and death decision is critical for all organisms. The balance of the related biological processes determines the cell fate. Most if not all prominent human diseases are affected by the dysregulation of cell death.

My lab focuses on the biochemcial mechanisms of autophagy and apoptosis in mammalian cells. The knowledge from our studies will help to identify drug-able targets and screen small-molecule compounds to interefere these activities, which should provide novel therapeuitc tools for the treatment of human diseases including cancers.