Lethal inflammasome activation by a multidrug-resistant pathobiont upon antibiotic disruption of the microbiota (2012)

Ayres JS, Trinidad NJ, Vance RE

Nat Med. 2012 Apr 22. doi: 10.1038/nm.2729

STING is a direct innate immune sensor of cyclic di-GMP (2011)

Burdette DL, Monroe KM, Sotelo-Troha K, Iwig JS, Eckert B, Hyodo M, Hayakawa Y, Vance RE

Nature. 2011 Sep 25;478(7370):515-8. doi: 10.1038/nature10429

Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity

Kofoed EM, Vance RE

Nature. 2011 Aug 28;477(7366):592-5. doi:10.1038/nature10394

Secreted bacterial effectors that inhibit host protein synthesis are critical for induction of the innate immune response to Legionella pneumophila (2011)

Fontana MF, Banga S, Barry KC, Shen X, Tan Y, Luo Z-Q, Vance RE

PLoS Pathogens epub February 17, 2011

Differential requirements for NAIP5 in activation of the NLRC4 (IPAF) inflammasome (2011)

Lightfield KL*, Persson J*, Trinidad NJ, Brubaker SW, Kofoed EM, Sauer J-D, Dunipace EA, Warren SE, Miao EA, Vance RE

* contributed equally

Infection & Immunity epub January 31, 2011

The N-Ethyl-N-Nitrosourea-Induced Goldenticket Mouse Mutant Reveals an Essential Function of Sting in the In Vivo Interferon Response to Listeria monocytogenes and Cyclic Dinucleotides (2011)

Sauer JD, Sotelo-Troha K, von Moltke J, Monroe KM, Rae CS, Brubaker SW, Hyodo M, Hayakawa Y, Woodward JJ, Portnoy DA, Vance RE

Infect Immun. 2011 Feb;79(2):688-94. Epub 2010 Nov 22.

Differential requirement for Caspase-1 autoproteolysis in pathogen-induced cell death and cytokine processing (2010)

Broz P*, von Moltke J*, Jones JW, Vance RE, Monack DM

* contributed equally

Cell Host Microbe. 2010 Dec 16;8(6):471-83

H-NOX regulation of c-di-GMP metabolism and biofilm formation in Legionella pneumophila (2010)

Carlson HK, Vance RE, Marletta MA

Mol Microbiol. Jun 21. [Epub ahead of print]

Identification of host cytosolic sensors and bacterial factors regulating the type I interferon response to Legionella pneumophila (2009)

Monroe KM, McWhirter SM, Vance RE

PLoS Pathog. 2009 Nov;5(11):e1000665. Epub 2009 Nov 20.

A host type I interferon response is induced by cytosolic sensing of the bacterial second messenger cyclic-di-GMP (2009)

McWhirter SM, Barbalat R, Monroe KM, Fontana MF, Hyodo M, Joncker NT, Ishii KJ, Akira S, Colonna M, Chen ZJ, Fitzgerald KA, Hayakawa Y, Vance RE

J Exp Med. 2009 Aug 31;206(9):1899-911. Epub 2009 Aug 3.

Critical function for Naip5 in inflammasome activation by a conserved carboxy-terminal domain of flagellin (2008)

Lightfield KL*, Persson J*, Brubaker SW, Witte CE, von Moltke J, Dunipace EA, Henry T, Sun YH, Cado D, Dietrich WF, Monack DM, Tsolis RM, Vance RE

* contributed equally

Nat Immunol. 2008 Oct;9(10):1171-8. Epub 2008 Aug 24