Bibliography 2012 Membrane-protein binding measured with solution-phase plasmonic nanocube sensors . Wu HJ, Henzie J, Lin WC, Rhodes C, Li Z, Sartorel E, Thorner J, Yang P, Groves JT. Nature Methods. 2012 Oct 21. doi 10.1038/nmeth.2211 [Epub ahead of print] Pub Med Abstract Reciprocal phosphorylation of yeast glycerol-3-phosphate dehydrogenases in adaptation to distinct types of stress. Lee YJ, Jeschke GR, Roelants RM, Thorner J, Turk BE. Mol Cell Biol. 2012 Nov;32(22):4705-4717. Pub Med Abstract Three-dimensional ultrastructure of the septin filament network in Saccharomyces cerevisiae. Bertin A, McMurray MA, Pierson J, Thai L, McDonald KL, Zehr EA, Garcia G 3rd, Peters P, Thorner J, Nogales E. Mol Biol Cell. 2012 Feb;23(3):423-432. Pub Med Abstract   2011 Subunit-dependent modulation of septin assembly: budding yeast septin Shs1 promotes ring and gauze formation. Garcia G 3rd, Bertin A, Li Z, Song Y, McMurray MA, Thorner J, Nogales E. J Cell Biol. 2011 Dec 12;195(6):993-1004. Pub Med Abstract Protein kinase Ypk1 phosphorylates regulatory proteins Orm1 and Orm2 to control sphingolipid homeostasis in Saccharomyces cerevisiae. Roelants FM, Breslow DK, Muir A, Weissman JS, Thorner J. Proc Natl Acad Sci USA. 2011 Nov 29;108(48):19222-19227. Pub Med Abstract Genetic interactions with mutations affecting septin assembly reveal ESCRT functions in budding yeast cytokenesis. McMurray MA, Stefan CJ, Wemmer M, Odorizzi G, Emr SD, Thorner J. Biol Chem. 2011 Aug;392(8-9):699-712. Pub Med Abstract Septin filament formation is essential in budding yeast. McMurray MA, Bertin A, Garcia G 3rd, Lam L, Nogales E, Thorner J. Dev Cell. 2011 Apr 19;20(4):540-9. Pub Med Abstract Structure of a Ca2+-myristoyl switch protein that controls activation of a phosphatidylinositol 4-kinase in fission yeast. Lim S, Strahl T, Thorner J, Ames JB. J Biol Chem. 2011 Apr 8;286(14):12565-77. Pub Med Abstract   2010 Single-cell analysis reveals that insulation maintains signaling specificity between two yeast MAPK pathways with common components. Patterson JC, Klimenko ES, Thorner J. Sci Signal. 2010 Oct 19;3(144):ra75. Pub Med Abstract Phosphatidylinositol-4,5-bisphosphate promotes budding yeast septin filament assembly and organization. Bertin A, McMurray MA, Thai L, Garcia G 3rd, Votin V, Grob P, Allyn T, Thorner J, Nogales E. J Mol Biol. 2010 Dec 10;404(4):711-31. Epub 2010 Oct 15. Pub Med Free Text Dynamic localization of Fus3 mitogen-activated protein kinase is necessary to evoke appropriate responses and avoid cytotoxic effects. Chen RE, Patterson JC, Goupil LS, Thorner J. Mol Cell Biol. 2010 Sep;30(17):4293-307. Epub 2010 Jun 28. Pub Med Free Text Pheromone-induced anisotropy in yeast plasma membrane phosphatidylinositol-4,5-bisphosphate distribution is required for MAPK signaling. Garrenton LS, Stefan CJ, McMurray MA, Emr SD, Thorner J. Proc Natl Acad Sci U S A. 2010 Jun 29;107(26):11805-10. Epub 2010 Jun 14. Pub Med Free Text Systematic epistasis analysis of the contributions of protein kinase A- and mitogen-activated protein kinase-dependent signaling to nutrient limitation-evoked responses in the yeast Saccharomyces cerevisiae. Chen RE, Thorner J. Genetics. 2010 Jul;185(3):855-70. Epub 2010 Apr 26 Pub Med Free Text A protein kinase network regulates the function of aminophospholipid flippases. Roelants FM, Baltz AG, Trott AE, Fereres S, Thorner J. Proc Natl Acad Sci U S A. 2010 Jan 5;107(1):34-9. Epub 2009 Dec 4. Pub Med Free Text   2009 Septins: molecular partitioning and the generation of cellular asymmetry. McMurray MA, Thorner J. Cell Div. 2009 Aug 26;4:18. Pub Med Free Text ABC transporter Pdr10 regulates the membrane microenvironment of Pdr12 in Saccharomyces cerevisiae. Rockwell NC, Wolfger H, Kuchler K, Thorner J. J Membr Biol. 2009 May;229(1):27-52. Epub 2009 May 19 Pub Med Free Text Reuse, replace, recycle. Specificity in subunit inheritance and assembly of higher-order septin structures during mitotic and meiotic division in budding yeast. McMurray MA, Thorner J. Cell Cycle. 2009 Jan 15;8(2):195-203. Review. Pub Med Abstract Nucleus-specific and cell cycle-regulated degradation of mitogen-activated protein kinase scaffold protein Ste5 contributes to the control of signaling competence. Garrenton LS, Braunwarth A, Irniger S, Hurt E, Künzler M, Thorner J. Mol Cell Biol. 2009 Jan;29(2):582-601. Epub 2008 Nov 10. Pub Med Free Text   2008 Stress resistance and signal fidelity independent of nuclear MAPK function. Westfall PJ, Patterson JC, Chen RE, Thorner J. Proc Natl Acad Sci U S A. 2008 Aug 26;105(34):12212-7. Epub 2008 Aug 21. Pub Med Free Text Septin stability and recycling during dynamic structural transitions in cell division and development. McMurray MA, Thorner J. Curr Biol. 2008 Aug 26;18(16):1203-8. Epub 2008 Aug 14. Pub Med Free Text Saccharomyces cerevisiae septins: supramolecular organization of heterooligomers and the mechanism of filament assembly. Bertin A, McMurray MA, Grob P, Park SS, Garcia G 3rd, Patanwala I, Ng HL, Alber T, Thorner J, Nogales E. Proc Natl Acad Sci U S A. 2008 Jun 17;105(24):8274-9. Epub 2008 Jun 12. Pub Med Free Text The 2008 Novitski Prize. Thomas J. Silhavy. Thorner JW. Genetics. 2008 Mar;178(3):1135-6. Pub Med Free Text   2007 An adrenaline (and gold?) rush for the GPCR community. Blumer KJ, Thorner J. ACS Chem Biol. 2007 Dec 21;2(12):783-6. Pub Med Abstract Membrane-active compounds activate the transcription factors Pdr1 and Pdr3 connecting pleiotropic drug resistance and membrane lipid homeostasis in Saccharomyces cerevisiae. Schüller C, Mamnun YM, Wolfger H, Rockwell N, Thorner J, Kuchler K. Mol Biol Cell. 2007 Dec;18(12):4932-44. Epub 2007 Sep 19. Pub Med Free Text Structural insights into activation of phosphatidylinositol 4-kinase (Pik1) by yeast frequenin (Frq1). Strahl T, Huttner IG, Lusin JD, Osawa M, King D, Thorner J, Ames JB. J Biol Chem. 2007 Oct 19;282(42):30949-59. Epub 2007 Aug 24. Pub Med Abstract Function and regulation in MAPK signaling pathways: lessons learned from the yeast Saccharomyces cerevisiae. Chen RE, Thorner J. Biochim Biophys Acta. 2007 Aug;1773(8):1311-40. Epub 2007 May 22. Review. Pub Med Free Text Synthesis and function of membrane phosphoinositides in budding yeast, Saccharomyces cerevisiae. Strahl T, Thorner J. Biochim Biophys Acta. 2007 Mar;1771(3):353-404. Epub 2007 Feb 6. Review. Pub Med Free Text   2006 DEP-domain-mediated regulation of GPCR signaling responses. Ballon DR, Flanary PL, Gladue DP, Konopka JB, Dohlman HG, Thorner J. Cell. 2006 Sep 22;126(6):1079-93. Pub Med Abstract Analysis of mitogen-activated protein kinase signaling specificity in response to hyperosmotic stress: use of an analog-sensitive HOG1 allele. Westfall PJ , Thorner J. Eukaryot Cell. 2006 Aug;5(8):1215-28. Pub Med Free Text Direct phosphorylation and activation of a Nim1-related kinase Gin4 by Elm1 in budding yeast. Asano S, Park JE, Yu LR, Zhou M, Sakchaisri K, Park CJ, Kang YH, Thorner J, Veenstra TD, Lee KS. J Biol Chem. 2006 Jul 15;20(14):1946-58. Pub Med Free Text Function of the MAPK scaffold protein, Ste5, requires a cryptic PH domain. Garrenton LS, Young SL, Thorner J. Genes Dev. 2006 Sep 22;126(6):1079-93. Free Text Activation of the DExD/H-box protein Dbp5 by the nuclear-pore protein Gle1 and its coactivator InsP6 is required for mRNA export. Weirich CS, Erzberger JP, Flick JS, Berger JM, Thorner J, Weis K. Nat Cell Biol. 2006 Jul;8(7):668-76. Pub Med Abstract The RA domain of Ste50 adaptor protein is required for delivery of Ste11 to the plasma membrane in the filamentous growth signaling pathway of the yeast Saccharomyces cerevisiae. Truckses DM, Bloomekatz JE, Thorner J. Mol Cell Biol. 2006 Feb;26(3):912-28. Pub Med Free Text "Signal Transduction" in Landmark Papers in Yeast Biology Linder P, Shore D, Hall MN, Eds. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, pp. 193-210.   2005 Yeast phosphatidylinositol 4-kinase, Pik1, has essential roles at the Golgi and in the nucleus. Strahl T, Hama H, DeWald DB, Thorner J. J Cell Biol. 2005 Dec 19;171(6):967-979. Pub Med Free Text Systems biology approaches in cell signaling research. Chen RE, Thorner J. Genome Biol. 2005 6(10):235. Pub Med Free Text. Some assembly required: yeast septins provide the instruction manual. Versele M , Thorner J. Trends Cell Biol. 2005 Aug;15(8):414-424. Pub Med Free Text Reconstitution of the mammalian PI3K/PTEN/Akt pathway in yeast. Rodriguez-Escudero I, Roelants FM, Thorner J, Nombela C, Molina M, Cid VJ. Biochem J. 2005 Sep 1;390(Pt 2):613-623. Pub Med Free Text   2004 When the stress of your environment makes you go HOG wild. Westfall PJ, Ballon DR, Thorner J. Science. 2004 Nov 26; 306(5701):1511-1512. Pub Med Abstract Jekyll and Hyde in the microbial world. Truckses DM , Thorner J. Science. 2004 Nov 26;306(5701):1509-1511. Pub Med Abstract "Pheromone receptors (Yeast)" in Encyclopedia of Biological Chemistry. Konopka JB, Thorner JW; Lennarz WJ, Lane MD, eds. Elsevier Science, Inc., Oxford, UK, Vol. 3, pp 256-261. Differential roles of PDK1- annd PDK2-phosphorylation sites in the yeast AGC kinases Ypk1, Pkc1 and Sch9. Roelants FM, Torrance PD , Thorner J. Microbiology. 2004 Oct;150(Pt 10):3289-3304. Free Text Protein-protein interactions governing septin heteropentamer assembly and septin filament organization in Saccharomyces cerevisiae. Versele M, Gullbrand B, Shulewitz MJ, Cid VJ, Bahmanyar S, Chen RE, Barth P, Alber T , Thorner J. Mol Biol Cell. 2004 Oct15(10):4568-4583. Pub Med Free Text The kindest cuts of all: crystal structures of Kex2 and furin reveal secrets of precursor processing. Rockwell NC, Thorner JW. Trends Biochem Sci. 2004 Feb;29(2):80-87. Pub Med Abstract Coupling morphogenesis to mitotic entry. Sakchaisri K, Asano S, Yu LR, Shulewitz MJ, Park CJ, Park JE, Cho YW, Veenstra TD, Thorner J, Lee KS. Proc Natl Acad Sci USA. 2004 Mar 23;101(12):4124-4129. Pub Med Free Text Septin collar formation in budding yeast requires GTP binding and direct phosphorylation by the PAK, Cla4. Versele M , Thorner J. J Cell BIol. 2004 Mar 1;164(5):701-715. Pub Med Free Text Roles of phosphoinsitides and of Spo14p (phospholipase D)-generated phosphatidic acid during yeast sporulation. Rudge SA, Sciorra VA, Iwamoto M, Zhou C, Strahl T, Morris AJ, Thorner J, Engebrecht J. Mol Biol Cell. 2004 Jan;15(1):207-218. Pub Med Free Text   2003 Strahl T, Grafelmann B, Dannenberg J, Thorner J, and Pongs O. Conservation of regulatory function in calcium-binding proteins. Journal of Biological Chemistry 278(49): 49589-49599 (Dec 5) Abstract   Huttner IG, Strahl T, Osawa M, King DS, Ames JB and Thorner J. Molecular Interactions of Yeast Frequenin (Frq1) with the Phosphatidylinositol 4-Kinase Isoform, Pik1. Journal of Biological Chemistry 278(7):4862-4874 (Feb 14) Abstract   2002 Thorner, J. Life in the Atomic Age (Book Review of Cell Biology by TD Pollard and WC Earnshaw) Nature Cell Biol. 4:E286   Roelants FM, Torrance PD, Bezman N and Thorner J. Pkh1 and Pkh2 Differentially Phosphorylate and Activate Ypk1 and Ykr2 and Define Protein Kinase Modules Required for Maintenance of Cell Wall Integrity. Mol. Biol. Cell 13:3005-3028 (September) Abstract   2001 Thorner, J. Greasing the Wheels of Secretory Transport Nature Cell Biology 3(8):E196-E198 (August) Abstract   Cid, V.J., Shulewitz, M.J., McDonald, K.L. and Thorner, J. Dynamic Localization of the Swe1 Regulator Hs17 During the Saccharomyces cerevisiae Cell Cycle Molecular Biology of the Cell 12:1645-1669 (June) Abstract   Adamkewicz, J.I., Hansen, K.E., Prud'homme, W.A., Davis, J.L. and Thorner, J. High Affinity Interaction of Yeast Transcriptional Regulator, Mot1, with TATA Box-Binding Protein (TBP) Journal of Biological Chemistry 276(15):11883-11894 (April 13) Abstract   Bardwell, A.J., Flatauer, L.J., Matsukuma, K., Thorner, J. and Bardwell, L. A Conserved Docking Site in MEKs Mediates High-affinity Binding to MAP Kinases and Cooperates with a Scaffold Protein to Enhance Signal Transmission Journal of Biological Chemistry 276:10374-10386 (March 30) Abstract   Kunzler, M., Trueheart, J., Sette, C., Hurt, E. and Thorner, J. Mutations in the YRB1 Gene Encoding Yeast Ran-Binding-Protein-1 That Impair Nucleocytoplasmic Transport and Suppress Yeast Mating Defects Genetics 157:1089-1105 (March) Abstract   2000 Sette, C., Inouye, C.J., Stroschein, S.L., Iaquinta, P.J. and Thorner, J. Mutational Analysis Suggests That Activation of the Yeast Pheromone Response Mitogen-activated Protein Kinase Pathway Involves Conformational Changes in the Ste5 Scaffold Protein Molecular Biology of the Cell 11:4033-4049 (Nov) Abstract   Ames, J.B., Hendricks, K.B., Strahl, T., Huttner, I.G., Hamasaki, N. and Thorner, J. Structure and Calcium-Binding Properties of Frq1, a Novel Calcium Sensor in the Yeast Saccharomyces cerevisiae Biochemistry 39(40):12149-12161 Abstract   Adamkewicz, J.I., Mueller, C.G.F., Hansen, K.E., Prud'homme, W.A. and Thorner, J. Purification and Enzymic Properties of Mot1 ATPase, a Regulator of Basal Transcription in the Yeast Saccharomyces cerevisiae Journal of Biological Chemistry 275:21158-21168 (July 14) Abstract   Petersen, C., Orem, N., Trueheart, J., Thorner, J., and Macara, I.G. Random Mutagenesis and Functional Analysis of the Ran-binding Protein, RanBP1 Journal of Biological Chemistry 275:4081-4091 (February 11) Abstract 1999 Hama, H., Schnieders, E.A., Thorner, J., Takemoto, J.Y. and DeWald, D.B. Direct Involvement of Phosphatidylinositol 4-Phosphate in Secretion in the Yeast Saccharomyces cerevisiae Journal of Biological Chemistry 274:34294-34300 (Nov 26) Abstract   Shulewitz, M.J., Inouye, C.J.and Thorner, J. Hs17 localizes to a septin ring and serves as an adapter in a regulatory pathway that relieves tyrosine phosphorylation of Cdc28 protein kinase in Saccharomyces cerevisiae Molecular and Cellular Biology 19:7123-7137 (October 1999) Abstract   Hendricks, K.B., Wang, B.Q., Schnieders, E.A. and Thorner, J. Yeast homologue of neuronal frequenin is a regulator of phosphatidylinositol-4-OH kinase Nature Cell Biology 1:234-241 (August 1999) Abstract   Casamayor, A., Torrance, P.D., Kobayashi, T., Thorner, J. and Alessi, D.R. Functional counterparts of mammalian protein kinases PDK1 and SGK in budding yeast Current Biology 9:186-197 (Feb 1999) Abstract 1998 Bardwell, L., Cook J.G., Zhu-Shimoni, J., Voora, D. and Thorner, J. Differential regulation of transcription: repression by unactivated mitogen-activated protein kinase kss1 requires the dig1 and dig2 proteins. Proc. Natl. Acad. Sci. U.S.A. 95:15400-15405 (Dec 1998) Abstract Bardwell, L., Cook, J.G., Voora, D., Baggott, D.M. and Thorner, J. Repression of yeast Ste12 transcription factor by direct binding of unphosphorylated Kss1MAPK and its regulation by the Ste7 MEK. Genes and Development 12: 2887-2898 (Sept. 15, 1998) Abstract Stolz, L.E., Huynh, C.V., Thorner, J. and York, J.D. Identification and Characterization of an Essential Family of Inositol Polyphosphate 5-Phosphatases (INP51, INP52 and INP53 Gene Products) in the Yeast Saccharomyces cerevisiae. Genetics 148:1715-1729 (Apr 1998) Abstract   Flick, J.S. and Thorner, J. An Essential Function of a Phosphoinositide-Specific Phospholipase C Is Relieved by Inhibition of a Cyclin-Dependent Protein Kinase in the Yeast Saccharomyces cerevisiae. Genetics 148:33-46 (Jan 1998) Abstract 1997 Cook, J.G., Bardwell, L., Thorner, J. Inhibitory and Activating Functions for MAPK Kss1 in the S. cerevisiae filamentous-growth signalling pathway. Nature 390: 85-88 (November 6, 1997) Abstract   Inouye, C., Dhillon, N., Thorner, J. Ste5 RING-H2 Domain: Role in Ste4-Promoted Oligomerization for Yeast Pheromone Signaling. Science 278: 103-106 (October 3, 1997) Abstract   Inouye C., Dhillon, N., Durfee, T., Zambryski, P.C., Thorner, J. Mutational Analysis of STE5 in the Yeast Saccharomyces cerevisiae: Application of a Differential Interaction Trap Assay for Examining Protein-Protein Interactions. Genetics 147: 479-492 (October 1997) Abstract   Brazill DT; Thorner J; Martin GS. Mck1, a member of the glycogen synthase kinase 3 family of protein kinases, is a negative regulator of pyruvate kinase in the yeast Saccharomyces cerevisiae. J Bacteriol.179(13), 4415-4418 (1997) Abstract   Wilson LK; Dhillon N; Thorner J; Martin GS. Casein kinase II catalyzes tyrosine phosphorylation of the yeast nucleolar immunophilin Fpr3.J. Biol. Chem. 272(20), 12961-7 (1997) Abstract 1996 Melcher ML; Thorner J. Identification and characterization of the CLK1 gene product, a novel CaM kinase-like protein kinase from the yeast Saccharomyces cerevisiae. J. Biol. Chem. 271(47), 29958-68 (1996) Abstract   Cook JG; Bardwell L; Kron SJ; Thorner J. Two novel targets of the MAP kinase Kss1 are negative regulators of invasive growth in the yeast Saccharomyces cerevisiae. Genes Dev. 10(22), 2831-48 (1996) Abstract   Broach JR; Thorner J. High-throughput screening for drug discovery. Nature 384(6604 Suppl), 14-6 (1996) Abstract   Bardwell L; Thorner J. A conserved motif at the amino termini of MEKs might mediate high-affinity interaction with the cognate MAPKs. Trends Biochem. Sci. 21(10), 373-4 (1996) Abstract   Dohlman HG; Song J; Ma D; Courchesne WE; Thorner J. Sst2, a negative regulator of pheromone signaling in the yeast Saccharomyces cerevisiae: expression, localization, and genetic interaction and physical association with Gpa1 (the G-protein alpha subunit). Mol. Cell. Biol. 16(9), 5194-209 (1996) Abstract   Bardwell L; Cook JG; Chang EC; Cairns BR; Thorner J. Signaling in the yeast pheromone response pathway: specific and high-affinity interaction of the mitogen-activated protein (MAP) kinases Kss1 and Fus3 with the upstream MAP kinase kinase Ste7. Mol. Cell. Biol. 16, 3637-3650 (1996) Abstract   Swartzman EE; Viswanathan MN; Thorner J. The PAL1 gene product is a peroxisomal ATP-binding cassette transporter in the yeast Saccharomyces cerevisiae. J. Cell Biol. 132, 549-563 (1996) Abstract 1995 Jiang W; Lim MY; Yoon HJ; Thorner J; Martin GS; Carbon J. Overexpression of the yeast MCK1 protein kinase suppresses conditional mutations in centromere-binding protein genes CBF2 and CBF5. Mol Gen Genet 246, 360-366 (1995) Abstract   Ma D; Cook JG; Thorner J. Phosphorylation and localization of Kss1, a MAP kinase of the Saccharomyces cerevisiae pheromone response pathway. Mol Biol Cell 6, 889-909 (1995) Abstract   Wilson LK; Benton BM; Zhou S; Thorner J; Martin GS. The yeast immunophilin Fpr3 is a physiological substrate of the tyrosine-specific phosphoprotein phosphatase Ptp1. J Biol Chem 270, 25185-25193 (1995) Abstract   Harris E; Yaswen P; Thorner J. Gain-of-function mutations in a human calmodulin-like protein identify residues critical for calmodulin action in yeast. Mol Gen Genet 247, 137-147 (1995) Abstract 1994 Harris E; Watterson DM; Thorner J. Functional consequences in yeast of single-residue alterations in a consensus calmodulin. J Cell Sci 107, 3235-3249 (1994) Abstract   Bardwell L; Cook JG; Inouye CJ; Thorner J. Signal propagation and regulation in the mating pheromone response pathway of the yeast Saccharomyces cerevisiae. Dev Biol 166, 363-379 (1994) Abstract   Salama SR; Hendricks KB; Thorner J. G1 cyclin degradation: the PEST motif of yeast Cln2 is necessary, but not sufficient, for rapid protein turnover. Mol Cell Biol 14, 7953-7966 (1994) Abstract   Benton BM; Zang JH; Thorner J. A novel FK506- and rapamycin-binding protein (FPR3 gene product) in the yeast Saccharomyces cerevisiae is a proline rotamase localized to the nucleolus. J Cell Biol 127, 623-639 (1994) Abstract   Auble DT; Hansen KE; Mueller CG; Lane WS; Thorner J; Hahn S. Mot1, a global repressor of RNA polymerase II transcription, inhibits TBP binding to DNA by an ATP-dependent mechanism. Genes Dev. 8, 1920-34 (1994) Abstract   Florio M; Wilson LK; Trager JB; Thorner J; Martin GS. Aberrant protein phosphorylation at tyrosine is responsible for the growth-inhibitory action of pp60v-src expressed in the yeast Saccharomyces cerevisiae. Mol Biol Cell 5, 283-296 (1994) Abstract   Perler FB; Davis EO; Dean GE; Gimble FS; Jack WE; Neff N; Noren CJ; Thorner J; Belfort M. Protein splicing elements: inteins and exteins--a definition of terms and recommended nomenclature. Nucleic Acids Res 22, 1125-7 (1994) Abstract   Hasson MS; Blinder D; Thorner J; Jenness DD. Mutational activation of the STE5 gene product bypasses the requirement for G protein beta and gamma subunits in the yeast pheromone response pathway. Mol Cell Biol 14, 1054-65 (1994) Abstract 1993 Flanagan CA; Schnieders EA; Emerick AW; Kunisawa R; Admon A; Thorner J. Phosphatidylinositol 4-kinase: gene structure and requirement for yeast cell viability. Science 262, 1444-8 (1993) Abstract   Dohlman HG; Goldsmith P; Spiegel AM; Thorner J. Pheromone action regulates G-protein alpha-subunit myristoylation in the yeast Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 90, 9688-92 (1993) Abstract   Gimble FS; Thorner J. Purification and characterization of VDE, a site-specific endonuclease from the yeast Saccharomyces cerevisiae. J Biol Chem 268, 21844-53 (1993) Abstract   Lim MY; Dailey D; Martin GS; Thorner J. Yeast MCK1 protein kinase autophosphorylates at tyrosine and serine but phosphorylates exogenous substrates at serine and threonine. J Biol Chem 268, 21155-64 (1993) Abstract   Flick JS; Thorner J. Genetic and biochemical characterization of a phosphatidylinositol-specific phospholipase C in Saccharomyces cerevisiae. Mol Cell Biol 13, 5861-76 (1993) Abstract   Kuchler K; Dohlman HG; Thorner J. The a-factor transporter (STE6 gene product) and cell polarity in the yeast Saccharomyces cerevisiae. J Cell Biol 120, 1203-15 (1993) Abstract 1992 Kuchler K; Goransson HM; Viswanathan MN; Thorner J. Dedicated transporters for peptide export and intercompartmental traffic in the yeast Saccharomyces cerevisiae. Cold Spring Harb Symp Quant Biol 57, 579-92 (1992) (no abstract available)   Bremer MC; Gimble FS; Thorner J; Smith CL. VDE endonuclease cleaves Saccharomyces cerevisiae genomic DNA at a single site: physical mapping of the VMA1 gene. Nucleic Acids Res 20, 5484 (1992) (no abstract available)   Flanagan CA; Thorner J. Purification and characterization of a soluble phosphatidylinositol 4-kinase from the yeast Saccharomyces cerevisiae. J Biol Chem 267, 24117-25 (1992) Abstract   Kuchler K; Thorner J. Secretion of peptides and proteins lacking hydrophobic signal sequences: the role of adenosine triphosphate-driven membrane translocators. Endocr Rev 13, 499-514 (1992) Abstract   Cyert MS; Thorner J. Regulatory subunit (CNB1 gene product) of yeast Ca2+/calmodulin-dependent phosphoprotein phosphatases is required for adaptation to pheromone. Mol Cell Biol 12, 3460-9 (1992) Abstract   Gimble FS; Thorner J. Homing of a DNA endonuclease gene by meiotic gene conversion in Saccharomyces cerevisiae. Nature 357, 301-6 (1992) Abstract   Kuchler K; Thorner J. Functional expression of human mdr1 in the yeast Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 89, 2302-6 (1992) Abstract   Davis JL; Kunisawa R; Thorner J. A presumptive helicase (MOT1 gene product) affects gene expression and is required for viability in the yeast Saccharomyces cerevisiae. Mol Cell Biol 12, 1879-92 (1992) Abstract 1991 Fields FO; Thorner J. Genetic suppression analysis of the function of a protein kinase C (PKC1 gene product) in Saccharomyces cerevisiae cell cycle progression: the SKCd mutations. Cold Spring Harb Symp Quant Biol 56, 51-60 (1991) (no abstract available)   Dohlman HG; Thorner J; Caron MG; Lefkowitz RJ. Model systems for the study of seven-transmembrane-segment receptors. Annu. Rev. Biochem. 60, 653-688 (1991) (no abstract available)   Cyert MS; Kunisawa R; Kaim D; Thorner J. Yeast has homologs (CNA1 and CNA2 gene products) of mammalian calcineurin, a calmodulin-regulated phosphoprotein phosphatase [published erratum appears in Proc Natl Acad Sci U S A 1992 May 1;89(9):4220] Proc Natl Acad Sci U S A 88, 7376-80 (1991) Abstract   Pausch MH; Kaim D; Kunisawa R; Admon A; Thorner J. Multiple Ca2+/calmodulin-dependent protein kinase genes in a unicellular eukaryote. EMBO J 10, 1511-22 (1991) Abstract 1990 Bresnahan PA; Leduc R; Thomas L; Thorner J; Gibson HL; Brake AJ; Barr PJ; Thomas G. Human fur gene encodes a yeast KEX2-like endoprotease that cleaves pro-beta-NGF in vivo. J Cell Biol 111, 2851-9 (1990) Abstract   Kuchler K; Thorner J. Membrane translocation of proteins without hydrophobic signal peptides. Curr Opin Cell Biol 2, 617-24 (1990) (no abstract available)   Dailey D; Schieven GL; Lim MY; Marquardt H; Gilmore T; Thorner J; Martin GS. Novel yeast protein kinase (YPK1 gene product) is a 40-kilodalton phosphotyrosyl protein associated with protein-tyrosine kinase activity [published erratum appears in Mol Cell Biol 1991 Apr;11(4):2333] Mol Cell Biol 10, 6244-56 (1990) Abstract   Marr RS; Blair LC; Thorner J. Saccharomyces cerevisiae STE14 gene is required for COOH-terminal methylation of a-factor mating pheromone. J Biol Chem 265, 20057-60 (1990) Abstract   King K; Dohlman HG; Thorner J; Caron MG; Lefkowitz RJ. Control of yeast mating signal transduction by a mammalian beta 2-adrenergic receptor and Gs alpha subunit [published erratum appears in Science 1991 Jan 11;251(4990):144] Science 250, 121-3 (1990) Abstract   Levin DE; Fields FO; Kunisawa R; Bishop JM; Thorner J. A candidate protein kinase C gene, PKC1, is required for the S. cerevisiae cell cycle. Cell 62, 213-24 (1990) Abstract   Blumer KJ; Thorner J. Beta and gamma subunits of a yeast guanine nucleotide-binding protein are not essential for membrane association of the alpha subunit but are required for receptor coupling. Proc Natl Acad Sci U S A 87, 4363-7 (1990) Abstract 1989 Yu L; Blumer KJ; Davidson N; Lester HA; Thorner J. Functional expression of the yeast alpha-factor receptor in Xenopus oocytes. J Biol Chem 264, 20847-50 (1989) Abstract   Kuchler K; Sterne RE; Thorner J. Saccharomyces cerevisiae STE6 gene product: a novel pathway for protein export in eukaryotic cells. EMBO J 8, 3973-84 (1989) Abstract   Fuller RS; Brake AJ; Thorner J. Intracellular targeting and structural conservation of a prohormone-processing endoprotease. Science 246, 482-6 (1989) Abstract   Davis TN; Thorner J. Vertebrate and yeast calmodulin, despite significant sequence divergence, are functionally interchangeable. Proc Natl Acad Sci U S A 86, 7909-13 (1989) Abstract   Courchesne WE; Kunisawa R; Thorner J. A putative protein kinase overcomes pheromone-induced arrest of cell cycling in S. cerevisiae. Cell 58, 1107-19 (1989) Abstract   Schafer WR; Kim R; Sterne R; Thorner J; Kim SH; Rine J. Genetic and pharmacological suppression of oncogenic mutations in ras genes of yeast and humans. Science 245, 379-85 (1989) Abstract   Cyert MS; Thorner J. Putting it on and taking it off: phosphoprotein phosphatase involvement in cell cycle regulation. Cell 57, 891-3 (1989) (no abstract available)   Flessel MC; Brake AJ; Thorner J. The MF alpha 1 gene of Saccharomyces cerevisiae: genetic mapping and mutational analysis of promoter elements. Genetics 121, 223-36 (1989) Abstract   Fuller RS; Brake A; Thorner J. Yeast prohormone processing enzyme (KEX2 gene product) is a Ca2+-dependent serine protease. Proc Natl Acad Sci U S A 86, 1434-8 (1989) Abstract References and abstracts were obtained from NCBI. Return to Top