Thorner Bibliography


 

 

Publications


2020

Network news: reporting from the frontlines of cell signaling (editorial overview).
Ablasser A, Thorner J
Curr Opin Cell Biol 2020, 63: iii-v. PMID: 32278627


2019

Turning it inside out: The organization of human septin heterooligomers.
McMurray MA, Thorner J
Cytoskeleton (Hoboken) 2019, 76 (9-10): 449-456. PMID: 31614074

Regulation of TORC2 function and localization by Rab5 GTPases in Saccharomyces cerevisiae.
Locke MN, Thorner J
Cell Cycle 2019, 18 (10): 1084-1094. PMID: 31068077


Analysis of the roles of phosphatidylinositol-4,5-bisphosphate and individual subunits in assembly, localization, and function of Saccharomyces cerevisiae target of rapamycin complex 2.
Martinez Marshall MN, Emmerstorfer-Augustin A, Leskoske KL, Zhang LH, Li B, Thorner J
Mol Biol Cell 2019, 30 (12): 1555-1574. PMID: 30969890


Rab5 GTPases are required for optimal TORC2 function.
Locke MN, Thorner J
J Cell Biol 2019, 218 (3): 961-976. PMID: 30578283


Septin-associated proteins Aim44 and Nis1 traffic between the bud neck and the nucleus in the yeast Saccharomyces cerevisiae.
Perez AM, Thorner J
Cytoskeleton (Hoboken) 2019, 76 (1): 15-32. PMID: 30341817



2018

Phosphorylation by the stress-activated MAPK Slt2 down-regulates the yeast TOR complex 2.
Leskoske KL, Roelants FM, Emmerstorfer-Augustin A, Augustin CM, Si EP, Hill JM, Thorner J
Genes Dev 2018, 32 (23-24): 1576-1590. PMID: 30478248


Tracking yeast pheromone receptor Ste2 endocytosis using fluorogen-activating protein tagging.
Emmerstorfer-Augustin A, Augustin CM, Shams S, Thorner J
Mol Biol Cell 2018, 29 (22): 2720-2736. PMID: 30207829


TOR complex 2-regulated protein kinase Ypk1 controls sterol distribution by inhibiting StARkin domain-containing proteins located at plasma membrane-endoplasmic reticulum contact sites.
Roelants FM, Chauhan N, Muir A, Davis JC, Menon AK, Levine TP, Thorner J
Mol Biol Cell 2018, 29 (17): 2128-2136. PMID: 29927351



2017

The TORC2-Dependent Signaling Network in the Yeast Saccharomyces cerevisiae.
Roelants FM, Leskoske KL, Martinez Marshall MN, Locke MN, Thorner J
Biomolecules 2017, 7 (3): E66.1-E66.41. PMID: 28872598


The Stress-Sensing TORC2 Complex Activates Yeast AGC-Family Protein Kinase Ypk1 at Multiple Novel Sites.
Leskoske KL, Roelants FM, Martinez Marshall MN, Hill JM, Thorner J
Genetics 2017, 207 (1): 179-195. PMID: 28739659


TOR Complex 2-Regulated Protein Kinase Fpk1 Stimulates Endocytosis via Inhibition of Ark1/Prk1-Related Protein Kinase Akl1 in Saccharomyces cerevisiae.
Roelants FM, Leskoske KL, Pedersen RTA, Muir A, Liu JM, Finnigan GC, Thorner J
Mol Cell Biol 2017, 37 (7): e00627-16.1-e00627-16.22. PMID: 28069741


Cell Signaling: Principles & Mechanisms
Thorner J
(Lim W et al.). - Book Review. Q. Rev. Biol. 92: 105-106.



2016

Septin-Associated Protein Kinases in the Yeast Saccharomyces cerevisiae.
Perez AM, Finnigan GC, Roelants FM, Thorner J
Front Cell Dev Biol 2016, 4: e119.1-e119.12. PMID: 27847804


Effects of Bni5 Binding on Septin Filament Organization.
Booth EA, Sterling SM, Dovala D, Nogales E, Thorner J
J Mol Biol 2016, 428 (24 Pt B): 4962-4980. PMID: 27806918


Internalization of Heterologous Sugar Transporters by Endogenous α-Arrestins in the Yeast Saccharomyces cerevisiae.
Sen A, Acosta-Sampson L, Alvaro CG, Ahn JS, Cate JH, Thorner J
Appl Environ Microbiol 2016, 82 (24): 7074-7085. PMID: 27694235


Sphingolipid biosynthesis upregulation by TOR complex 2-Ypk1 signaling during yeast adaptive response to acetic acid stress.
Guerreiro JF, Muir A, Ramachandran S, Thorner J, Sá-Correia I
Biochem J 2016, 473 (23): 4311-4325. PMID: 27671892


A FRET-based method for monitoring septin polymerization and binding of septin-associated proteins.
Booth EA, Thorner J
Methods Cell Biol 2016, 136: 35-56. PMID: 27473902


Detection of protein-protein interactions at the septin collar in Saccharomyces cerevisiae using a tripartite split-GFP system.
Finnigan GC, Duvalyan A, Liao EN, Sargsyan A, Thorner J
Mol Biol Cell 2016, 27 (17): 2708-25. PMID: 27385335


Coordinate action of distinct sequence elements localizes checkpoint kinase Hsl1 to the septin collar at the bud neck in Saccharomyces cerevisiae.
Finnigan GC, Sterling SM, Duvalyan A, Liao EN, Sargsyan A, Garcia G 3rd, Nogales E, Thorner J
Mol Biol Cell 2016, 27 (14): 2213-33. PMID: 27193302


mCAL: A New Approach for Versatile Multiplex Action of Cas9 Using One sgRNA and Loci Flanked by a Programmed Target Sequence.
Finnigan GC, Thorner J
G3 (Bethesda) 2016, 6 (7): 2147-56. PMID: 27185399


Assembly, molecular organization, and membrane-binding properties of development-specific septins.
Garcia G 3rd, Finnigan GC, Heasley LR, Sterling SM, Aggarwal A, Pearson CG, Nogales E, McMurray MA, Thorner J
J Cell Biol 2016, 212 (5): 515-29. PMID: 26929450


Differential Phosphorylation Provides a Switch to Control How α-Arrestin Rod1 Down-regulates Mating Pheromone Response in Saccharomyces cerevisiae.
Alvaro CG, Aindow A, Thorner J
Genetics 2016, 203 (1): 299-317. PMID: 26920760


Heterotrimeric G Protein-coupled Receptor Signaling in Yeast Mating Pheromone Response.
Alvaro CG, Thorner J
J Biol Chem 2016, 291 (15): 7788-95. PMID: 26907689


Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Arozena AA, Adachi H, Adams CM, Adams PD, Adeli K, ..., Thorner J, ..., et al. [over 2,400 authors]
Autophagy 2016, 12 (1): 1-222. PMID: 26799652



2015

Complex in vivo Ligation Using Homologous Recombination and High-efficiency Plasmid Rescue from Saccharomyces cerevisiae.
Finnigan GC, Thorner J
Bio Protoc 2015, 5 (13): . PMID: 26523287


α-Arrestins participate in cargo selection for both clathrin-independent and clathrin-mediated endocytosis.
Prosser DC, Pannunzio AE, Brodsky JL, Thorner J, Wendland B, O'Donnell AF
J Cell Sci 2015, 128 (22): 4220-34. PMID: 26459639


A Förster Resonance Energy Transfer (FRET)-based System Provides Insight into the Ordered Assembly of Yeast Septin Hetero-octamers.
Booth EA, Vane EW, Dovala D, Thorner J
J Biol Chem 2015, 290 (47): 28388-401. PMID: 26416886


Down-regulation of TORC2-Ypk1 signaling promotes MAPK-independent survival under hyperosmotic stress.
Muir A, Roelants FM, Timmons G, Leskoske KL, Thorner J
Elife 2015, 4: e09336.1-e09336.13. PMID: 26274562


The Carboxy-Terminal Tails of Septins Cdc11 and Shs1 Recruit Myosin-II Binding Factor Bni5 to the Bud Neck in Saccharomyces cerevisiae.
Finnigan GC, Booth EA, Duvalyan A, Liao EN, Thorner J
Genetics 2015, 200 (3): 843-62. PMID: 25971666


Comprehensive Genetic Analysis of Paralogous Terminal Septin Subunits Shs1 and Cdc11 in Saccharomyces cerevisiae.
Finnigan GC, Takagi J, Cho C, Thorner J
Genetics 2015, 200 (3): 821-41. PMID: 25971665


Cytosolic chaperones mediate quality control of higher-order septin assembly in budding yeast.
Johnson CR, Weems AD, Brewer JM, Thorner J, McMurray MA
Mol Biol Cell 2015, 26 (7): 1323-44. PMID: 25673805


Protein kinase Gin4 negatively regulates flippase function and controls plasma membrane asymmetry.
Roelants FM, Su BM, von Wulffen J, Ramachandran S, Sartorel E, Trott AE, Thorner J
J Cell Biol 2015, 208 (3): 299-311. PMID: 25646086


2-Deoxyglucose impairs Saccharomyces cerevisiae growth by stimulating Snf1-regulated and α-arrestin-mediated trafficking of hexose transporters 1 and 3.
O'Donnell AF, McCartney RR, Chandrashekarappa DG, Zhang BB, Thorner J, Schmidt MC
Mol Cell Biol 2015, 35 (6): 939-55. PMID: 25547292


Plasma membrane aminoglycerolipid flippase function is required for signaling competence in the yeast mating pheromone response pathway.
Sartorel E, Barrey E, Lau RK, Thorner J
Mol Biol Cell 2015, 26 (1): 134-50. PMID: 25378585



2014

Signal transduction: From the atomic age to the post-genomic era.
Thorner J, Hunter T, Cantley LC, Sever R
Cold Spring Harb Perspect Biol 2014, 6 (12): a022913. PMID: 25359498


TORC2-dependent protein kinase Ypk1 phosphorylates ceramide synthase to stimulate synthesis of complex sphingolipids.
Muir A, Ramachandran S, Roelants FM, Timmons G, Thorner J
Elife 2014, 3: e03779.1-e03779.34. PMID: 25279700


Specific α-arrestins negatively regulate Saccharomyces cerevisiae pheromone response by down-modulating the G-protein-coupled receptor Ste2.
Alvaro CG, O'Donnell AF, Prosser DC, Augustine AA, Goldman A, Brodsky JL, Cyert MS, Wendland B, Thorner J
Mol Cell Biol 2014, 34 (14): 2660-81. PMID: 24820415


Signal Transduction: Principles, Pathways, and Processes.
Cantley LC, Hunter T, Sever R, Thorner J (eds.)
Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, 452pp., 2014.



2013

A calcineurin-dependent switch controls the trafficking function of α-arrestin Aly1/Art6.
O'Donnell AF, Huang L, Thorner J, Cyert MS
J Biol Chem 2013, 288 (33): 24063-80. PMID: 23824189


Native cysteine residues are dispensable for the structure and function of all five yeast mitotic septins.
de Val N, McMurray MA, Lam LH, Hsiung CC, Bertin A, Nogales E, Thorner J
Proteins 2013, 81 (11): 1964-79. PMID: 23775754


Pheromone Receptors (Yeast).
Konopka JB, Thorner JW
In: Lennarz WJ, Lane MD (eds.) The Encyclopedia of Biological Chemistry, 2nd Ed. Vol. 3, pp. 441-446. Waltham, MA: Academic Press, Inc. (2013)



2012

Membrane-protein binding measured with solution-phase plasmonic nanocube sensors.
Wu HJ, Henzie J, Lin WC, Rhodes C, Li Z, Sartorel E, Thorner J, Yang P, Groves JT
Nat Methods 2012, 9 (12): 1189-91. PMID: 23085614


Reciprocal phosphorylation of yeast glycerol-3-phosphate dehydrogenases in adaptation to distinct types of stress.
Lee YJ, Jeschke GR, Roelants FM, Thorner J, Turk BE
Mol Cell Biol 2012, 32 (22): 4705-17. PMID: 22988299


Three-dimensional ultrastructure of the septin filament network in Saccharomyces cerevisiae.
Bertin A, McMurray MA, Pierson J, Thai L, McDonald KL, Zehr EA, García G 3rd, Peters P, Thorner J, Nogales E
Mol Biol Cell 2012, 23 (3): 423-32. PMID: 22160597



2011

Subunit-dependent modulation of septin assembly: budding yeast septin Shs1 promotes ring and gauze formation.
Garcia G 3rd, Bertin A, Li Z, Song Y, McMurray MA, Thorner J, Nogales E
J Cell Biol 2011, 195 (6): 993-1004. PMID: 22144691


Protein kinase Ypk1 phosphorylates regulatory proteins Orm1 and Orm2 to control sphingolipid homeostasis in Saccharomyces cerevisiae.
Roelants FM, Breslow DK, Muir A, Weissman JS, Thorner J
Proc Natl Acad Sci U S A 2011, 108 (48): 19222-7. PMID: 22080611


Genetic interactions with mutations affecting septin assembly reveal ESCRT functions in budding yeast cytokinesis.
McMurray MA, Stefan CJ, Wemmer M, Odorizzi G, Emr SD, Thorner J
Biol Chem 2011, 392 (8-9): 699-712. PMID: 21824003


Septin filament formation is essential in budding yeast.
McMurray MA, Bertin A, Garcia G 3rd, Lam L, Nogales E, Thorner J
Dev Cell 2011, 20 (4): 540-9. PMID: 21497764


Structure of a Ca2+-myristoyl switch protein that controls activation of a phosphatidylinositol 4-kinase in fission yeast.
Lim S, Strahl T, Thorner J, Ames JB
J Biol Chem 2011, 286 (14): 12565-77. PMID: 21288895



2010

Single-cell analysis reveals that insulation maintains signaling specificity between two yeast MAPK pathways with common components.
Patterson JC, Klimenko ES, Thorner J
Sci Signal 2010, 3 (144): ra75. PMID: 20959523


Phosphatidylinositol-4,5-bisphosphate promotes budding yeast septin filament assembly and organization.
Bertin A, McMurray MA, Thai L, Garcia G 3rd, Votin V, Grob P, Allyn T, Thorner J, Nogales E
J Mol Biol 2010, 404 (4): 711-31. PMID: 20951708


Dynamic localization of Fus3 mitogen-activated protein kinase is necessary to evoke appropriate responses and avoid cytotoxic effects.
Chen RE, Patterson JC, Goupil LS, Thorner J
Mol Cell Biol 2010, 30 (17): 4293-307. PMID: 20584989


Pheromone-induced anisotropy in yeast plasma membrane phosphatidylinositol-4,5-bisphosphate distribution is required for MAPK signaling.
Garrenton LS, Stefan CJ, McMurray MA, Emr SD, Thorner J
Proc Natl Acad Sci U S A 2010, 107 (26): 11805-10. PMID: 20547860


Systematic epistasis analysis of the contributions of protein kinase A- and mitogen-activated protein kinase-dependent signaling to nutrient limitation-evoked responses in the yeast Saccharomyces cerevisiae.
Chen RE, Thorner J
Genetics 2010, 185 (3): 855-70. PMID: 20421603


A protein kinase network regulates the function of aminophospholipid flippases.
Roelants FM, Baltz AG, Trott AE, Fereres S, Thorner J
Proc Natl Acad Sci U S A 2010, 107 (1): 34-9. PMID: 19966303



2009

Septins: molecular partitioning and the generation of cellular asymmetry.
McMurray MA, Thorner J
Cell Div 2009, 4: 18. PMID: 19709431


ABC transporter Pdr10 regulates the membrane microenvironment of Pdr12 in Saccharomyces cerevisiae.
Rockwell NC, Wolfger H, Kuchler K, Thorner J
J Membr Biol 2009, 229 (1): 27-52. PMID: 19452121


Reuse, replace, recycle. Specificity in subunit inheritance and assembly of higher-order septin structures during mitotic and meiotic division in budding yeast.
McMurray MA, Thorner J
Cell Cycle 2009, 8 (2): 195-203. PMID: 19164941


Nucleus-specific and cell cycle-regulated degradation of mitogen-activated protein kinase scaffold protein Ste5 contributes to the control of signaling competence.
Garrenton LS, Braunwarth A, Irniger S, Hurt E, Künzler M, Thorner J
Mol Cell Biol 2009, 29 (2): 582-601. PMID: 19001089



2008

Stress resistance and signal fidelity independent of nuclear MAPK function.
Westfall PJ, Patterson JC, Chen RE, Thorner J
Proc Natl Acad Sci U S A 2008, 105 (34): 12212-7. PMID: 18719124


Septin stability and recycling during dynamic structural transitions in cell division and development.
McMurray MA, Thorner J
Curr Biol 2008, 18 (16): 1203-8. PMID: 18701287


Saccharomyces cerevisiae septins: supramolecular organization of heterooligomers and the mechanism of filament assembly.
Bertin A, McMurray MA, Grob P, Park SS, Garcia G 3rd, Patanwala I, Ng HL, Alber T, Thorner J, Nogales E
Proc Natl Acad Sci U S A 2008, 105 (24): 8274-9. PMID: 18550837


The 2008 Novitski Prize. Thomas J. Silhavy.
Thorner JW
Genetics 2008, 178 (3): 1135-6. PMID: 18385107



2007

An adrenaline (and gold?) rush for the GPCR community.
Blumer KJ, Thorner J
ACS Chem Biol 2007, 2 (12): 783-6. PMID: 18154265


Membrane-active compounds activate the transcription factors Pdr1 and Pdr3 connecting pleiotropic drug resistance and membrane lipid homeostasis in saccharomyces cerevisiae.
Schüller C, Mamnun YM, Wolfger H, Rockwell N, Thorner J, Kuchler K
Mol Biol Cell 2007, 18 (12): 4932-44. PMID: 17881724


Structural insights into activation of phosphatidylinositol 4-kinase (Pik1) by yeast frequenin (Frq1).
Strahl T, Huttner IG, Lusin JD, Osawa M, King D, Thorner J, Ames JB
J Biol Chem 2007, 282 (42): 30949-59. PMID: 17720810


Function and regulation in MAPK signaling pathways: lessons learned from the yeast Saccharomyces cerevisiae.
Chen RE, Thorner J
Biochim Biophys Acta 2007, 1773 (8): 1311-40. PMID: 17604854


Synthesis and function of membrane phosphoinositides in budding yeast, Saccharomyces cerevisiae.
Strahl T, Thorner J
Biochim Biophys Acta 2007, 1771 (3): 353-404. PMID: 17382260



2006

DEP-domain-mediated regulation of GPCR signaling responses.
Ballon DR, Flanary PL, Gladue DP, Konopka JB, Dohlman HG, Thorner J
Cell 2006, 126 (6): 1079-93. PMID: 16990133


Analysis of mitogen-activated protein kinase signaling specificity in response to hyperosmotic stress: use of an analog-sensitive HOG1 allele.
Westfall PJ, Thorner J
Eukaryot Cell 2006, 5 (8): 1215-28. PMID: 16896207


Direct phosphorylation and activation of a Nim1-related kinase Gin4 by Elm1 in budding yeast.
Asano S, Park JE, Yu LR, Zhou M, Sakchaisri K, Park CJ, Kang YH, Thorner J, Veenstra TD, Lee KS
J Biol Chem 2006, 281 (37): 27090-8. PMID: 16861226


Function of the MAPK scaffold protein, Ste5, requires a cryptic PH domain.
Garrenton LS, Young SL, Thorner J
Genes Dev 2006, 20 (14): 1946-58. PMID: 16847350


Activation of the DExD/H-box protein Dbp5 by the nuclear-pore protein Gle1 and its coactivator InsP6 is required for mRNA export.
Weirich CS, Erzberger JP, Flick JS, Berger JM, Thorner J, Weis K
Nat Cell Biol 2006, 8 (7): 668-76. PMID: 16783364


The RA domain of Ste50 adaptor protein is required for delivery of Ste11 to the plasma membrane in the filamentous growth signaling pathway of the yeast Saccharomyces cerevisiae.
Truckses DM, Bloomekatz JE, Thorner J
Mol Cell Biol 2006, 26 (3): 912-28. PMID: 16428446


"Signal Transduction" in Landmark Papers in Yeast Biology
Linder P, Shore D, Hall MN, Eds.
Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, pp. 193-210.


2005

Yeast phosphatidylinositol 4-kinase, Pik1, has essential roles at the Golgi and in the nucleus.
Strahl T, Hama H, DeWald DB, Thorner J
J Cell Biol 2005, 171 (6): 967-79. PMID: 16365163


Systems biology approaches in cell signaling research.
Chen RE, Thorner J
Genome Biol 2005, 6 (10): 235. PMID: 16207364


Some assembly required: yeast septins provide the instruction manual.
Versele M, Thorner J
Trends Cell Biol 2005, 15 (8): 414-24. PMID: 16009555


Reconstitution of the mammalian PI3K/PTEN/Akt pathway in yeast.
Rodríguez-Escudero I, Roelants FM, Thorner J, Nombela C, Molina M, Cid VJ
Biochem J 2005, 390 (Pt 2): 613-23. PMID: 15913452



2004

When the stress of your environment makes you go HOG wild.
Westfall PJ, Ballon DR, Thorner J
Science 2004, 306 (5701): 1511-2. PMID: 15567851


"Pheromone receptors (Yeast)" in Encyclopedia of Biological Chemistry.
Konopka JB, Thorner JW; Lennarz WJ, Lane MD, eds.
Elsevier Science, Inc., Oxford, UK, Vol. 3, pp 256-261.


Jekyll and Hyde in the microbial world.
Truckses DM, Garrenton LS, Thorner J
Science 2004, 306 (5701): 1509-11. PMID: 15567850


Differential roles of PDK1- and PDK2-phosphorylation sites in the yeast AGC kinases Ypk1, Pkc1 and Sch9.
Roelants FM, Torrance PD, Thorner J
Microbiology 2004, 150 (Pt 10): 3289-304. PMID: 15470109


Protein-protein interactions governing septin heteropentamer assembly and septin filament organization in Saccharomyces cerevisiae.
Versele M, Gullbrand B, Shulewitz MJ, Cid VJ, Bahmanyar S, Chen RE, Barth P, Alber T, Thorner J
Mol Biol Cell 2004, 15 (10): 4568-83. PMID: 15282341


The kindest cuts of all: crystal structures of Kex2 and furin reveal secrets of precursor processing.
Rockwell NC, Thorner JW
Trends Biochem Sci 2004, 29 (2): 80-7. PMID: 15102434


Coupling morphogenesis to mitotic entry.
Sakchaisri K, Asano S, Yu LR, Shulewitz MJ, Park CJ, Park JE, Cho YW, Veenstra TD, Thorner J, Lee KS
Proc Natl Acad Sci U S A 2004, 101 (12): 4124-9. PMID: 15037762


Septin collar formation in budding yeast requires GTP binding and direct phosphorylation by the PAK, Cla4.
Versele M, Thorner J
J Cell Biol 2004, 164 (5): 701-15. PMID: 14993234


Roles of phosphoinositides and of Spo14p (phospholipase D)-generated phosphatidic acid during yeast sporulation.
Rudge SA, Sciorra VA, Iwamoto M, Zhou C, Strahl T, Morris AJ, Thorner J, Engebrecht J
Mol Biol Cell 2004, 15 (1): 207-18. PMID: 14528019



2003

Conservation of regulatory function in calcium-binding proteins: human frequenin (neuronal calcium sensor-1) associates productively with yeast phosphatidylinositol 4-kinase isoform, Pik1.
Strahl T, Grafelmann B, Dannenberg J, Thorner J, Pongs O
J Biol Chem 2003, 278 (49): 49589-99. PMID: 14512421


Regulation of Ste7 ubiquitination by Ste11 phosphorylation and the Skp1-Cullin-F-box complex.
Wang Y, Ge Q, Houston D, Thorner J, Errede B, Dohlman HG
J Biol Chem 2003, 278 (25): 22284-9. PMID: 12668671


Molecular interactions of yeast frequenin (Frq1) with the phosphatidylinositol 4-kinase isoform, Pik1.
Huttner IG, Strahl T, Osawa M, King DS, Ames JB, Thorner J
J Biol Chem 2003, 278 (7): 4862-74. PMID: 12477731



2002

Pkh1 and Pkh2 differentially phosphorylate and activate Ypk1 and Ykr2 and define protein kinase modules required for maintenance of cell wall integrity.
Roelants FM, Torrance PD, Bezman N, Thorner J
Mol Biol Cell 2002, 13 (9): 3005-28. PMID: 12221112


Orchestrating the cell cycle in yeast: sequential localization of key mitotic regulators at the spindle pole and the bud neck.
Cid VJ, Jiménez J, Molina M, Sánchez M, Nombela C, Thorner JW
Microbiology 2002, 148 (Pt 9): 2647-59. PMID: 12213912


Direct and novel regulation of cAMP-dependent protein kinase by Mck1p, a yeast glycogen synthase kinase-3.
Rayner TF, Gray JV, Thorner JW
J Biol Chem 2002, 277 (19): 16814-22. PMID: 11877433


Life in the Atomic Age: Cell Biology by Thomas D. Pollard and William C. Earnshaw.
Thorner J.
Nat Cell Biol. 2002 4:E286. Book Review.


2001

Greasing the wheels of secretory transport.
Thorner JW
Nat Cell Biol 2001, 3 (8): E196-8. PMID: 11483981


Dynamic localization of the Swe1 regulator Hsl7 during the Saccharomyces cerevisiae cell cycle.
Cid VJ, Shulewitz MJ, McDonald KL, Thorner J
Mol Biol Cell 2001, 12 (6): 1645-69. PMID: 11408575


Regulation of G protein-initiated signal transduction in yeast: paradigms and principles.
Dohlman HG, Thorner JW
Annu Rev Biochem 2001, 70 (): 703-54. PMID: 11395421


High affinity interaction of yeast transcriptional regulator, Mot1, with TATA box-binding protein (TBP).
Adamkewicz JI, Hansen KE, Prud'homme WA, Davis JL, Thorner J
J Biol Chem 2001, 276 (15): 11883-94. PMID: 11278722


Mutations in the YRB1 gene encoding yeast ran-binding-protein-1 that impair nucleocytoplasmic transport and suppress yeast mating defects.
Künzler M, Trueheart J, Sette C, Hurt E, Thorner J
Genetics 2001, 157 (3): 1089-105. PMID: 11238397


A conserved docking site in MEKs mediates high-affinity binding to MAP kinases and cooperates with a scaffold protein to enhance signal transmission.
Bardwell AJ, Flatauer LJ, Matsukuma K, Thorner J, Bardwell L
J Biol Chem 2001, 276 (13): 10374-86. PMID: 11134045



2000

Mutational analysis suggests that activation of the yeast pheromone response mitogen-activated protein kinase pathway involves conformational changes in the Ste5 scaffold protein.
Sette C, Inouye CJ, Stroschein SL, Iaquinta PJ, Thorner J
Mol Biol Cell 2000, 11 (11): 4033-49. PMID: 11071925


Structure and calcium-binding properties of Frq1, a novel calcium sensor in the yeast Saccharomyces cerevisiae.
Ames JB, Hendricks KB, Strahl T, Huttner IG, Hamasaki N, Thorner J
Biochemistry 2000, 39 (40): 12149-61. PMID: 11015193


Purification and enzymic properties of Mot1 ATPase, a regulator of basal transcription in the yeast Saccharomyces cerevisiae.
Adamkewicz JI, Mueller CG, Hansen KE, Prud'homme WA, Thorner J
J Biol Chem 2000, 275 (28): 21158-68. PMID: 10887203


Random mutagenesis and functional analysis of the Ran-binding protein, RanBP1.
Petersen C, Orem N, Trueheart J, Thorner JW, Macara IG
J Biol Chem 2000, 275 (6): 4081-91. PMID: 10660567



1999

Direct involvement of phosphatidylinositol 4-phosphate in secretion in the yeast Saccharomyces cerevisiae.
Hama H, Schnieders EA, Thorner J, Takemoto JY, DeWald DB
J Biol Chem 1999, 274 (48): 34294-300. PMID: 10567405


Yeast homologue of neuronal frequenin is a regulator of phosphatidylinositol-4-OH kinase.
Hendricks KB, Wang BQ, Schnieders EA, Thorner J
Nat Cell Biol 1999, 1 (4): 234-41. PMID: 10559922


Hsl7 localizes to a septin ring and serves as an adapter in a regulatory pathway that relieves tyrosine phosphorylation of Cdc28 protein kinase in Saccharomyces cerevisiae.
Shulewitz MJ, Inouye CJ, Thorner J
Mol Cell Biol 1999, 19 (10): 7123-37. PMID: 10490648


Functional counterparts of mammalian protein kinases PDK1 and SGK in budding yeast.
Casamayor A, Torrance PD, Kobayashi T, Thorner J, Alessi DR
Curr Biol 1999, 9 (4): 186-97. PMID: 10074427



1998

Differential regulation of transcription: repression by unactivated mitogen-activated protein kinase Kss1 requires the Dig1 and Dig2 proteins.
Bardwell L, Cook JG, Zhu-Shimoni JX, Voora D, Thorner J
Proc Natl Acad Sci U S A 1998, 95 (26): 15400-5. PMID: 9860980


Repression of yeast Ste12 transcription factor by direct binding of unphosphorylated Kss1 MAPK and its regulation by the Ste7 MEK.
Bardwell L, Cook JG, Voora D, Baggott DM, Martinez AR, Thorner J
Genes Dev 1998, 12 (18): 2887-98. PMID: 9744865


Identification and characterization of an essential family of inositol polyphosphate 5-phosphatases (INP51, INP52 and INP53 gene products) in the yeast Saccharomyces cerevisiae.
Stolz LE, Huynh CV, Thorner J, York JD
Genetics 1998, 148 (4): 1715-29. PMID: 9560389


An essential function of a phosphoinositide-specific phospholipase C is relieved by inhibition of a cyclin-dependent protein kinase in the yeast Saccharomyces cerevisiae.
Flick JS, Thorner J
Genetics 1998, 148 (1): 33-47. PMID: 9475719



1997

Inhibitory and activating functions for MAPK Kss1 in the S. cerevisiae filamentous-growth signalling pathway.
Cook JG, Bardwell L, Thorner J
Nature 1997, 390 (6655): 85-8. PMID: 9363895


Mutational analysis of STE5 in the yeast Saccharomyces cerevisiae: application of a differential interaction trap assay for examining protein-protein interactions.
Inouye C, Dhillon N, Durfee T, Zambryski PC, Thorner J
Genetics 1997, 147 (2): 479-92. PMID: 9335587


Ste5 RING-H2 domain: role in Ste4-promoted oligomerization for yeast pheromone signaling.
Inouye C, Dhillon N, Thorner J
Science 1997, 278 (5335): 103-6. PMID: 9311911


Mck1, a member of the glycogen synthase kinase 3 family of protein kinases, is a negative regulator of pyruvate kinase in the yeast Saccharomyces cerevisiae.
Brazill DT, Thorner J, Martin GS
J Bacteriol 1997, 179 (13): 4415-8. PMID: 9209064


Expression and purification of the Saccharomyces cerevisiae alpha-factor receptor (Ste2p), a 7-transmembrane-segment G protein-coupled receptor.
David NE, Gee M, Andersen B, Naider F, Thorner J, Stevens RC
J Biol Chem 1997, 272 (24): 15553-61. PMID: 9182592


Casein kinase II catalyzes tyrosine phosphorylation of the yeast nucleolar immunophilin Fpr3.
Wilson LK, Dhillon N, Thorner J, Martin GS
J Biol Chem 1997, 272 (20): 12961-7. PMID: 9148902


RGS proteins and signaling by heterotrimeric G proteins.
Dohlman HG, Thorner J
J Biol Chem 1997, 272 (7): 3871-4. PMID: 9064301



1996

Identification and characterization of the CLK1 gene product, a novel CaM kinase-like protein kinase from the yeast Saccharomyces cerevisiae.
Melcher ML, Thorner J
J Biol Chem 1996, 271 (47): 29958-68. PMID: 8939941


Two novel targets of the MAP kinase Kss1 are negative regulators of invasive growth in the yeast Saccharomyces cerevisiae.
Cook JG, Bardwell L, Kron SJ, Thorner J
Genes Dev 1996, 10 (22): 2831-48. PMID: 8918885


A conserved motif at the amino termini of MEKs might mediate high-affinity interaction with the cognate MAPKs.
Bardwell L, Thorner J
Trends Biochem Sci 1996, 21 (10): 373-4. PMID: 8918190


High-throughput screening for drug discovery.
Broach JR, Thorner J
Nature 1996, 384 (6604 Suppl): 14-6. PMID: 8895594


Immunophilins in the Yeast Saccharomyces cerevisiae: A Different Spin on Proline Rotamases
Dhillon N, Thorner J
Methods 1996, 9 (2): 165-76. PMID: 8812661


Sst2, a negative regulator of pheromone signaling in the yeast Saccharomyces cerevisiae: expression, localization, and genetic interaction and physical association with Gpa1 (the G-protein alpha subunit).
Dohlman HG, Song J, Ma D, Courchesne WE, Thorner J
Mol Cell Biol 1996, 16 (9): 5194-209. PMID: 8756677


Signaling in the yeast pheromone response pathway: specific and high-affinity interaction of the mitogen-activated protein (MAP) kinases Kss1 and Fus3 with the upstream MAP kinase kinase Ste7.
Bardwell L, Cook JG, Chang EC, Cairns BR, Thorner J
Mol Cell Biol 1996, 16 (7): 3637-50. PMID: 8668180


The PAL1 gene product is a peroxisomal ATP-binding cassette transporter in the yeast Saccharomyces cerevisiae.
Swartzman EE, Viswanathan MN, Thorner J
J Cell Biol 1996, 132 (4): 549-63. PMID: 8647887



1995

Overexpression of the yeast MCK1 protein kinase suppresses conditional mutations in centromere-binding protein genes CBF2 and CBF5.
Jiang W, Lim MY, Yoon HJ, Thorner J, Martin GS, Carbon J
Mol Gen Genet 1995, 246 (3): 360-6. PMID: 7854321


Gain-of-function mutations in a human calmodulin-like protein identify residues critical for calmodulin action in yeast.
Harris E, Yaswen P, Thorner J
Mol Gen Genet 1995, 247 (2): 137-47. PMID: 7753022


Phosphorylation and localization of Kss1, a MAP kinase of the Saccharomyces cerevisiae pheromone response pathway.
Ma D, Cook JG, Thorner J
Mol Biol Cell 1995, 6 (7): 889-909. PMID: 7579701


The yeast immunophilin Fpr3 is a physiological substrate of the tyrosine-specific phosphoprotein phosphatase Ptp1.
Wilson LK, Benton BM, Zhou S, Thorner J, Martin GS
J Biol Chem 1995, 270 (42): 25185-93. PMID: 7559654



1994

Mutational activation of the STE5 gene product bypasses the requirement for G protein beta and gamma subunits in the yeast pheromone response pathway.
Hasson MS, Blinder D, Thorner J, Jenness DD
Mol Cell Biol 1994, 14 (2): 1054-65. PMID: 8289786


Protein splicing elements: inteins and exteins--a definition of terms and recommended nomenclature.
Perler FB, Davis EO, Dean GE, Gimble FS, Jack WE, Neff N, Noren CJ, Thorner J, Belfort M
Nucleic Acids Res 1994, 22 (7): 1125-7. PMID: 8165123


Aberrant protein phosphorylation at tyrosine is responsible for the growth-inhibitory action of pp60v-src expressed in the yeast Saccharomyces cerevisiae.
Florio M, Wilson LK, Trager JB, Thorner J, Martin GS
Mol Biol Cell 1994, 5 (3): 283-96. PMID: 8049521


G1 cyclin degradation: the PEST motif of yeast Cln2 is necessary, but not sufficient, for rapid protein turnover.
Salama SR, Hendricks KB, Thorner J
Mol Cell Biol 1994, 14 (12): 7953-66. PMID: 7969135


Mot1, a global repressor of RNA polymerase II transcription, inhibits TBP binding to DNA by an ATP-dependent mechanism.
Auble DT, Hansen KE, Mueller CG, Lane WS, Thorner J, Hahn S
Genes Dev 1994, 8 (16): 1920-34. PMID: 7958867


Signal propagation and regulation in the mating pheromone response pathway of the yeast Saccharomyces cerevisiae.
Bardwell L, Cook JG, Inouye CJ, Thorner J
Dev Biol 1994, 166 (2): 363-79. PMID: 7813763


Functional consequences in yeast of single-residue alterations in a consensus calmodulin.
Harris E, Watterson DM, Thorner J
J Cell Sci 1994, 107 ( Pt 11) (): 3235-49. PMID: 7699020


A novel FK506- and rapamycin-binding protein (FPR3 gene product) in the yeast Saccharomyces cerevisiae is a proline rotamase localized to the nucleolus.
Benton BM, Zang JH, Thorner J
J Cell Biol 1994, 127 (3): 623-39. PMID: 7525596



1993

Pheromone action regulates G-protein alpha-subunit myristoylation in the yeast Saccharomyces cerevisiae.
Dohlman HG, Goldsmith P, Spiegel AM, Thorner J
Proc Natl Acad Sci U S A 1993, 90 (20): 9688-92. PMID: 8415763


Purification and characterization of VDE, a site-specific endonuclease from the yeast Saccharomyces cerevisiae.
Gimble FS, Thorner J
J Biol Chem 1993, 268 (29): 21844-53. PMID: 8408039


Yeast MCK1 protein kinase autophosphorylates at tyrosine and serine but phosphorylates exogenous substrates at serine and threonine.
Lim MY, Dailey D, Martin GS, Thorner J
J Biol Chem 1993, 268 (28): 21155-64. PMID: 8407952


Genetic and biochemical characterization of a phosphatidylinositol-specific phospholipase C in Saccharomyces cerevisiae.
Flick JS, Thorner J
Mol Cell Biol 1993, 13 (9): 5861-76. PMID: 8395015


Phosphatidylinositol 4-kinase: gene structure and requirement for yeast cell viability.
Flanagan CA, Schnieders EA, Emerick AW, Kunisawa R, Admon A, Thorner J
Science 1993, 262 (5138): 1444-8. PMID: 8248783


The a-factor transporter (STE6 gene product) and cell polarity in the yeast Saccharomyces cerevisiae.
Kuchler K, Dohlman HG, Thorner J
J Cell Biol 1993, 120 (5): 1203-15. PMID: 7679674



1992

Homing of a DNA endonuclease gene by meiotic gene conversion in Saccharomyces cerevisiae.
Gimble FS, Thorner J
Nature 1992, 357 (6376): 301-6. PMID: 1534148


VDE endonuclease cleaves Saccharomyces cerevisiae genomic DNA at a single site: physical mapping of the VMA1 gene.
Bremer MC, Gimble FS, Thorner J, Smith CL
Nucleic Acids Res 1992, 20 (20): 5484. PMID: 1437572


Secretion of peptides and proteins lacking hydrophobic signal sequences: the role of adenosine triphosphate-driven membrane translocators.
Kuchler K, Thorner J
Endocr Rev 1992, 13 (3): 499-514. PMID: 1425485


Functional expression of human mdr1 in the yeast Saccharomyces cerevisiae.
Kuchler K, Thorner J
Proc Natl Acad Sci U S A 1992, 89 (6): 2302-6. PMID: 1347948


Dedicated transporters for peptide export and intercompartmental traffic in the yeast Saccharomyces cerevisiae.
Kuchler K, Göransson HM, Viswanathan MN, Thorner J
Cold Spring Harb Symp Quant Biol 1992, 57 (): 579-92. PMID: 1339696


Purification and characterization of a soluble phosphatidylinositol 4-kinase from the yeast Saccharomyces cerevisiae.
Flanagan CA, Thorner J
J Biol Chem 1992, 267 (33): 24117-25. PMID: 1331109


Regulatory subunit (CNB1 gene product) of yeast Ca2+/calmodulin-dependent phosphoprotein phosphatases is required for adaptation to pheromone.
Cyert MS, Thorner J
Mol Cell Biol 1992, 12 (8): 3460-9. PMID: 1321337


A presumptive helicase (MOT1 gene product) affects gene expression and is required for viability in the yeast Saccharomyces cerevisiae.
Davis JL, Kunisawa R, Thorner J
Mol Cell Biol 1992, 12 (4): 1879-92. PMID: 1312673



1991

Multiple Ca2+/calmodulin-dependent protein kinase genes in a unicellular eukaryote.
Pausch MH, Kaim D, Kunisawa R, Admon A, Thorner J
EMBO J 1991, 10 (6): 1511-22. PMID: 2026147


Receptor-G protein signaling in yeast.
Blumer KJ, Thorner J
Annu Rev Physiol 1991, 53 (): 37-57. PMID: 1904209


Genetic suppression analysis of the function of a protein kinase C (PKC1 gene product) in Saccharomyces cerevisiae cell cycle progression: the SKCd mutations.
Fields FO, Thorner J
Cold Spring Harb Symp Quant Biol 1991, 56 (): 51-60. PMID: 1819504


Model systems for the study of seven-transmembrane-segment receptors.
Dohlman HG, Thorner J, Caron MG, Lefkowitz RJ
Annu Rev Biochem 1991, 60 (): 653-88. PMID: 1652922


Yeast has homologs (CNA1 and CNA2 gene products) of mammalian calcineurin, a calmodulin-regulated phosphoprotein phosphatase.
Cyert MS, Kunisawa R, Kaim D, Thorner J
Proc Natl Acad Sci U S A 1991, 88 (16): 7376-80. PMID: 1651503



1990

Novel yeast protein kinase (YPK1 gene product) is a 40-kilodalton phosphotyrosyl protein associated with protein-tyrosine kinase activity.
Dailey D, Schieven GL, Lim MY, Marquardt H, Gilmore T, Thorner J, Martin GS
Mol Cell Biol 1990, 10 (12): 6244-56. PMID: 1701015


Human fur gene encodes a yeast KEX2-like endoprotease that cleaves pro-beta-NGF in vivo.
Bresnahan PA, Leduc R, Thomas L, Thorner J, Gibson HL, Brake AJ, Barr PJ, Thomas G
J Cell Biol 1990, 111 (6 Pt 2): 2851-9. PMID: 2269657


Membrane translocation of proteins without hydrophobic signal peptides.
Kuchler K, Thorner J
Curr Opin Cell Biol 1990, 2 (4): 617-24. PMID: 2252588


A candidate protein kinase C gene, PKC1, is required for the S. cerevisiae cell cycle.
Levin DE, Fields FO, Kunisawa R, Bishop JM, Thorner J
Cell 1990, 62 (2): 213-24. PMID: 2196995


Saccharomyces cerevisiae STE14 gene is required for COOH-terminal methylation of a-factor mating pheromone.
Marr RS, Blair LC, Thorner J
J Biol Chem 1990, 265 (33): 20057-60. PMID: 2173693


Control of yeast mating signal transduction by a mammalian beta 2-adrenergic receptor and Gs alpha subunit.
King K, Dohlman HG, Thorner J, Caron MG, Lefkowitz RJ
Science 1990, 250 (4977): 121-3. PMID: 2171146


Beta and gamma subunits of a yeast guanine nucleotide-binding protein are not essential for membrane association of the alpha subunit but are required for receptor coupling.
Blumer KJ, Thorner J
Proc Natl Acad Sci U S A 1990, 87 (11): 4363-7. PMID: 2161538



1989

Saccharomyces cerevisiae STE6 gene product: a novel pathway for protein export in eukaryotic cells.
Kuchler K, Sterne RE, Thorner J
EMBO J 1989, 8 (13): 3973-84. PMID: 2686977


Intracellular targeting and structural conservation of a prohormone-processing endoprotease.
Fuller RS, Brake AJ, Thorner J
Science 1989, 246 (4929): 482-6. PMID: 2683070


A putative protein kinase overcomes pheromone-induced arrest of cell cycling in S. cerevisiae.
Courchesne WE, Kunisawa R, Thorner J
Cell 1989, 58 (6): 1107-19. PMID: 2673544


The MF alpha 1 gene of Saccharomyces cerevisiae: genetic mapping and mutational analysis of promoter elements.
Flessel MC, Brake AJ, Thorner J
Genetics 1989, 121 (2): 223-36. PMID: 2659433


Yeast prohormone processing enzyme (KEX2 gene product) is a Ca2+-dependent serine protease.
Fuller RS, Brake A, Thorner J
Proc Natl Acad Sci U S A 1989, 86 (5): 1434-8. PMID: 2646633


Genetic and pharmacological suppression of oncogenic mutations in ras genes of yeast and humans.
Schafer WR, Kim R, Sterne R, Thorner J, Kim SH, Rine J
Science 1989, 245 (4916): 379-85. PMID: 2569235


Functional expression of the yeast alpha-factor receptor in Xenopus oocytes.
Yu L, Blumer KJ, Davidson N, Lester HA, Thorner J
J Biol Chem 1989, 264 (35): 20847-50. PMID: 2556384


Vertebrate and yeast calmodulin, despite significant sequence divergence, are functionally interchangeable.
Davis TN, Thorner J
Proc Natl Acad Sci U S A 1989, 86 (20): 7909-13. PMID: 2554295


Putting it on and taking it off: phosphoprotein phosphatase involvement in cell cycle regulation.
Cyert MS, Thorner J
Cell 1989, 57 (6): 891-3. PMID: 2544293


Nucleotidylation, not phosphorylation, is the major source of the phosphotyrosine detected in enteric bacteria.
Foster R, Thorner J, Martin GS
J Bacteriol 1989, 171 (1): 272-9. PMID: 2464577



1988

Yeast KEX2 endopeptidase correctly cleaves a neuroendocrine prohormone in mammalian cells.
Thomas G, Thorne BA, Thomas L, Allen RG, Hruby DE, Fuller R, Thorner J
Science 1988, 241 (4862): 226-30. PMID: 3291117


Enzymes required for yeast prohormone processing.
Fuller RS, Sterne RE, Thorner J
Annu Rev Physiol 1988, 50 (): 345-62. PMID: 3288097


Functional domains of a peptide hormone receptor: the alpha-factor receptor (STE2 gene product) of the yeast Saccharomyces cerevisiae.
Blumer KJ, Reneke JE, Courchesne WE, Thorner J
Cold Spring Harb Symp Quant Biol 1988, 53 Pt 2 (): 591-603. PMID: 2855497


The carboxy-terminal segment of the yeast alpha-factor receptor is a regulatory domain.
Reneke JE, Blumer KJ, Courchesne WE, Thorner J
Cell 1988, 55 (2): 221-34. PMID: 2844413


The STE2 gene product is the ligand-binding component of the alpha-factor receptor of Saccharomyces cerevisiae.
Blumer KJ, Reneke JE, Thorner J
J Biol Chem 1988, 263 (22): 10836-42. PMID: 2839507



1987

Complete nucleotide sequence of the gene encoding the regulatory subunit of 3',5'-cyclic AMP-dependent protein kinase from the yeast Saccharomyces cerevisiae.
Kunisawa R, Davis TN, Urdea MS, Thorner J
Nucleic Acids Res 1987, 15 (1): 368-9. PMID: 3547325


The yeast repeated element sigma contains a hormone-inducible promoter.
Van Arsdell SW, Stetler GL, Thorner J
Mol Cell Biol 1987, 7 (2): 749-59. PMID: 3547081


The yeast ARD1 gene product is required for repression of cryptic mating-type information at the HML locus.
Whiteway M, Freedman R, Van Arsdell S, Szostak JW, Thorner J
Mol Cell Biol 1987, 7 (10): 3713-22. PMID: 3316986


Isolation of the yeast calmodulin gene using synthetic oligonucleotide probes.
Davis TN, Thorner J
Methods Enzymol 1987, 139 (): 248-62. PMID: 3295478



1986

Protein-tyrosine kinase activity in Saccharomyces cerevisiae.
Schieven G, Thorner J, Martin GS
Science 1986, 231 (4736): 390-3. PMID: 2417318


Isolation of the yeast calmodulin gene: calmodulin is an essential protein.
Davis TN, Urdea MS, Masiarz FR, Thorner J
Cell 1986, 47 (3): 423-31. PMID: 3533275


Genetic manipulation of Saccharomyces cerevisiae by use of the LYS2 gene.
Barnes DA, Thorner J
Mol Cell Biol 1986, 6 (8): 2828-38. PMID: 3023949



1985

Pheromone-processing protease of the yeast Saccharomyces cerevisiae.
Thorner J
Nature 1985, 314 (6009): 384-5. PMID: 3885046



1984

Isolation of the putative structural gene for the lysine-arginine-cleaving endopeptidase required for processing of yeast prepro-alpha-factor.
Julius D, Brake A, Blair L, Kunisawa R, Thorner J
Cell 1984, 37 (3): 1075-89. PMID: 6430565


Glycosylation and processing of prepro-alpha-factor through the yeast secretory pathway.
Julius D, Schekman R, Thorner J
Cell 1984, 36 (2): 309-18. PMID: 6420074


Molecular cloning of hormone-responsive genes from the yeast Saccharomyces cerevisiae.
Stetler GL, Thorner J
Proc Natl Acad Sci U S A 1984, 81 (4): 1144-8. PMID: 6366798



1983

Cell interactions and regulation of cell type in the yeast Saccharomyces cerevisiae.
Sprague GF Jr, Blair LC, Thorner J
Annu Rev Microbiol 1983, 37 (): 623-60. PMID: 6357062


A functional prepro-alpha-factor gene in Saccharomyces yeasts can contain three, four, or five repeats of the mature pheromone sequence.
Brake AJ, Julius DJ, Thorner J
Mol Cell Biol 1983, 3 (8): 1440-50. PMID: 6353204


Extracellular suppression allows mating by pheromone-deficient sterile mutants of Saccharomyces cerevisiae.
Chan RK, Melnick LM, Blair LC, Thorner J
J Bacteriol 1983, 155 (2): 903-6. PMID: 6348031


Yeast alpha factor is processed from a larger precursor polypeptide: the essential role of a membrane-bound dipeptidyl aminopeptidase.
Julius D, Blair L, Brake A, Sprague G, Thorner J
Cell 1983, 32 (3): 839-52. PMID: 6339075


An MF alpha 1-SUC2 (alpha-factor-invertase) gene fusion for study of protein localization and gene expression in yeast.
Emr SD, Schekman R, Flessel MC, Thorner J
Proc Natl Acad Sci U S A 1983, 80 (23): 7080-4. PMID: 6359161



1982

Effect of halogenated pyrimidine 5'-mononucleotides on dTMP-permeable yeast strains and the isolation and characterization of resistant mutants.
Bisson LF, Thorner J
Mol Gen Genet 1982, 186 (4): 467-74. PMID: 6752656


Exogenous dTMP utilization by a novel tup mutant of Saccharomyces cerevisiae.
Bisson LF, Thorner J
J Bacteriol 1982, 152 (1): 111-9. PMID: 6749802


Mutations in the pho80 gene confer permeability to 5'-mononucleotides in Saccharomyces cerevisiae.
Bisson LF, Thorner J
Genetics 1982, 102 (3): 341-59. PMID: 6293915


Yeast mating pheromone activates mammalian gonadotrophs: evolutionary conservation of a reproductive hormone?
Loumaye E, Thorner J, Catt KJ
Science 1982, 218 (4579): 1323-5. PMID: 6293058


An essential role for cyclic AMP in growth control: the case for yeast.
Thorner J
Cell 1982, 30 (1): 5-6. PMID: 6290081



1981

Thymidylate synthetase from Saccharomyces cerevisiae. Purification and enzymic properties.
Bisson LF, Thorner J
J Biol Chem 1981, 256 (23): 12456-62. PMID: 7028756


Adenosine 3',5'-phosphate phosphodiesterase and pheromone response in the yeast Saccharomyces cerevisiae.
Liao HH, Thorner J
J Bacteriol 1981, 148 (3): 919-25. PMID: 6171560



1980

Yeast mating pheromone alpha factor inhibits adenylate cyclase.
Liao H, Thorner J
Proc Natl Acad Sci U S A 1980, 77 (4): 1898-902. PMID: 6246513



1979

Recovery of S. cerevisiae a cells from G1 arrest by alpha factor pheromone requires endopeptidase action.
Ciejek E, Thorner J
Cell 1979, 18 (3): 623-35. PMID: 391400



1978

Identification of tubulin from the yeast Saccharomyces cerevisiae.
Baum P, Thorner J, Honig L
Proc Natl Acad Sci U S A 1978, 75 (10): 4962-6. PMID: 368805


Cell-cell recognition in Saccharomyces cerevisiae: regulation of mating-specific adhesion.
Fehrenbacher G, Perry K, Thorner J
J Bacteriol 1978, 134 (3): 893-901. PMID: 350854



1977

Thymidine 5'-monophosphate-requiring mutants of Saccharomyces cerevisiae are deficient in thymidylate synthetase.
Bisson L, Thorner J
J Bacteriol 1977, 132 (1): 44-50. PMID: 334734


Solid phase peptide synthesis of alpha-factor, a yeast mating pheromone.
Ciejek E, Thorner J, Geier M
Biochem Biophys Res Commun 1977, 78 (3): 952-61. PMID: 334181



1975

Energy-dependent activation of the temperature-sensitive DNA polymerases induced by bacteriophage T4 gene 43 mutants.
Thorner J, Huang WM, Lehman IR
Virology 1975, 68 (2): 338-48. PMID: 1198924


Glycerol kinase.
Thorner JW
Methods Enzymol 1975, 42 (): 148-56. PMID: 237175


Metabolic and cardiovascular abnormalities in patients with peripheral arterial disease.
Vyden JK, Thorner J, Nagasawa K, Takano T, Groseth-Dittrich MF, Perlow R, Swan HJ
Am Heart J 1975, 90 (6): 703-8. PMID: 173169



1973

Catalytic and allosteric properties of glycerol kinase from Escherichia coli.
Thorner JW, Paulus H
J Biol Chem 1973, 248 (11): 3922-32. PMID: 4575199



1971

Composition and subunit structure of glycerol kinase from Escherichia coli.
Thorner JW, Paulus H
J Biol Chem 1971, 246 (12): 3885-94. PMID: 4934840




References and abstracts were obtained from NCBI.

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