Kim J, Kleizen B, Choy R, Thinakaran G, Sisodia SS, Schekman R.
Biogenesis of gamma-secretase early in the secretory pathway. J. Cell Biol. 179, 951-963 (2007). Abstract.
Fromme JC, Ravazzola M, Hamamoto S, Al-Balwi M, Eyaid W, Boyadjiev SA, Cosson P, Schekman R, Orci L.
The genetic basis of a craniofacial disease provides insight into COPII coat assembly. Dev. Cell 13, 623-634 (2007). Abstract.
Kim J, Thanabalasuriar A, Chaworth-Musters T, Fromme JC, Frey EA, Lario PI, Metalnikov P, Rizg K, Thomas NA, Lee SF, Hartland EL, Hardwidge PR, Pawson T, Strynadka NC, Finlay BB, Schekman R, Gruenheid S.
The Bacterial Virulence Factor NleA Inhibits Cellular Protein Secretion by Disrupting Mammalian COPII Function. Cell Host and Microbe 2, 160-171 (2007). Abstract.
Harsay, E., and Schekman, R.
Avl9p, a Member of a Novel Protein Superfamily, Functions in the Late Secretory Pathway. Mol. Biol. Cell. 18(4), 1203-19 (2007). Abstract.
Copic, A., Starr, T., and Schekman, R.
Ent3p and Ent5p Exhibit Cargo-specific Functions in Trafficking Proteins between the Trans-Golgi Network and the Endosomes in Yeast. Mol. Biol. Cell. 18(5), 1803-15 (2007). Abstract.
Boyadjiev SA, Fromme JC, Ben J, Chong SS, Nauta C, Hur DJ, Zhang G, Hamamoto S, Schekman R, Ravazzola M, Orci L, Eyaid W.
Cranio-lenticulo-sutural dysplasia is caused by a SEC23A mutation leading to abnormal ER-to-Golgi trafficking. Nature Genetics 38(10), 1192-1197 (2006). Abstract.
Wang, C. W., Hamamoto, S., Orci, L., and Schekman, R.
Exomer: a coat complex for transport of select membrane proteins from the trans-Golgi network to the plasma membrane in yeast. J. Cell Biol. 174(7), 973-983 (2006). Abstract.
Sanchatjate, S., and Schekman, R.
Chs5/6 Complex: A Multi-Protein Complex That Interacts with and Conveys Chitin Synthase III from the Trans-Golgi Network to the Cell Surface. Mol. Biol. Cell. 17(10), 4157-4166 (2006). Abstract.
Zagorski, N.
QnAs with Randy Schekman. PNAS 103(50), 18881 (2006). Article.
Bucci, M.
Randy Schekman. Nature Chemical Biology 2, 568 (2006). Article.
Lee, M.C.S., Orci, L., Hamamoto, S., Futai, E., Ravazzola, M., and Schekman, R.
Sar1p N-terminal helix initiates membrane curvature and completes the fission of a COPII vesicle. Cell 122, 605-617 (2005). Abstract.
Miller, E. A., Liu, Y., Barlowe, C., and Schekman, R.
ER-Golgi transport defects are associated with mutations in the Sed5p-binding domain of the COPII coat subunit, Sec24p. Mol. Biol. Cell. 16, 3719-3726 (2005). Abstract.
Fromme, J.C., and Schekman, R.
COPII-coated vesicles: flexible enough for large cargo? Curr. Opin. Cell Biol. 17, 345-352 (2005). Abstract.
Schekman, R.
Peroxisomes: another branch of the secretory pathway? Cell 122, 1-2 (2005). Abstract.
Futai, E., and Schekman, R.
Purification and functional properties of Sec12 GEF. Meth Enzymol. 404, 74-82 (2005). Abstract.
Wickner, William and Schekman, Randy.
Protein translocation across biological membranes. Science 310, 1452-1456 (2005). Abstract.
Schekman, R.
Membrane traffic in landmark papers in yeast biology, a chapter in Landmark Papers. Cold Spring Harbor Press (Eds. P. Linder, D. Shore and M. Hall) pgs. 243-252 (2005).
Kim, Jinoh, Hamamoto, Susan, Ravazzola, Mariella, Orci, Lelio, and Schekman, Randy.
Uncoupled packaging of amyloid precursor protein and presenilin 1 into COPII vesicles. J. Biol. Chem. 280, 7758-7768 (2004). Abstract.
Sun, Yidi, Kaksonen, Marko, Madden, David T., Schekman, Randy, and Drubin, David G.
Interaction of Sla2p's ANTH domain with PtdIns(4,5)P2 is important for actin-dependent endocytic internalization. Mol. Biol. Cell 16, 717-730 (2004). Abstract.
Malkus, Per, Graham, L. A., Stevens, T. H., and Schekman, Randy.
Role of Vma21p in assembly and transport of the yeast vacuolar ATPase. Mol. Biol. Cell 15, 5075-5091 (2004). Abstract.
Futai, Eugene, Hamamoto, Susan, Orci, Lelio and Schekman, Randy.
GTP/GDP exchange by Sec12p enables COPII vesicle bud formation on synthetic liposomes. EMBO J. 23, 4286-4296 (2004). Abstract.
Schekman, Randy.
A channel for protein waste. Nature 429, 817-818 (2004). Article.
Schekman, Randy.
Merging cultures in the study of membrane traffic. Nature Cell Biol. 6, 483-486 (2004). Abstract.
Lee, Marcus C. S., Miller, E. A., Goldberg, J., Orci, L., and Schekman, Randy.
Bi-directional protein transport between the ER and Golgi. Annu. Rev. Cell Dev. Biol. 20, 87-123 (2004). Abstract.
Kim, Jinoh, and Schekman, Randy.
The ins and outs of presenilin 1 membrane topology. PNAS 101, 905-906 (2004). Article.
Lee, Marcus C. S., and Schekman, R.
BAR domains go on a bender. Science 303, 479-480 (2004). Article.
Schekman, Randy, and Novick, Peter.
23 genes, 23 years later. Cell S116, S13-S15 (2004). Article.
Antonny, B., Gounon, P., Schekman, R., and Orci, L.
Self-assembly of minimal COPII cages. EMBO Reports 4, 419-424 (2003). Abstract.
Valdivia, R., and Schekman, R.
The yeast Rho1p and Pkc1p regulate the transport of chitin synthase III (Chs3p) from internal stores to the plasma membrane. Proc. Natl. Acad. Sci. USA 100,10287-10292 (2003). Abstract.
Miller, E., Beilharz, T. H., Malkus, P. N., Lee, M.C.S., Hamamoto, S., Orci, L., and Schekman, R.
Multiple cargo binding sites on the COPII subunit Sec24p ensure capture of diverse membrane proteins into transport vesicles. Cell 114, 1-20 (2003). Abstract.
Harsay, E., and Schekman, R.
A subset of yeast vacuolar protein sorting mutants are blocked in one branch of the exocytic pathway. J. Cell Biol. 156, 271-286 (2002). Abstract.
Valdivia, R. H., Baggott, D., Chuang, J. S., and Schekman, R. W.
The yeast clathrin adaptor protein complex-1 is required for the efficient retention of a subset of late-Golgi membrane proteins. Dev. Cell 2, 283-294 (2002). Abstract.
Marcus C.S. Lee, Susan Hamamoto, and Randy Schekman
Ceramide biosynthesis is required for the formation of oligomeric H+-ATPase, Pma1p, in the yeast endoplasmic reticulum .J. Biol. Chem., 277, 22395-22401 (2002). Abstract.
Shimoni, Y., and Schekman, R.
Vesicle budding from the ER. Meth. Enzymol. 351, 258-278 (2002).
Supek, F., Madden, D. T., Hamamoto, S., Orci, L., and Schekman, R.
Sec16p potentiates the action of COPII proteins to bud transport vesicles. J. Cell Biol. 158, 1029-1038 (2002). Abstract.
Miller, E., Antonny, B., Hamamoto, S., and Schekman, R.
Cargo selection into COPII vesicles is driven by the Sec24p subunit. EMBO J. 21, 6105-6113 (2002). Abstract.
Schekman, R.
SEC mutants and the secretory apparatus. Nature Medicine 8, 1055-1058 (2002).
Deloche, O., and Schekman, R. W.
Vps10p cycles between the TGN and the late endosome via the plasma membrane in clathrin mutants. Mol. Biol. Cell 13, 4296-4307 (2002). Abstract.
Malkus, P., Jiang, F., and Schekman, R.
Concentrative sorting of secretory cargo proteins into COPII-coated vesicles. J. Cell Biol. 159, 915-921 (2002). Abstract.
Deloche O, Yeung BG, Payne GS, Schekman R.
Vps10p Transport from the trans-Golgi Network to the Endosome Is Mediated by Clathrin-coated Vesicles. Mol Biol Cell. 12, 475-485 (2001). Abstract.
Spang, A., Herrmann, J. M., Hamamoto, S., and Schekman, R.
The ADP ribosylation factor-nucleotide exchange factors Gea1p and Gea2p have overlapping, but not redundant functions in retrograde transport from the Golgi to the endoplasmic reticulum. Mol. Biol. Cell 12, 1035-1045 (2001). Abstract.
Antonny, B., Madden, D., Hamamoto, S., Orci, L., and Schekman, R.
Dynamics of the COPII coat with GTP and stable analogues. Nature Cell Biol. 3, 531-537 (2001). Abstract.
Antonny, B., and Schekman, R.
ER export: Public transportation by the COPII coach. Curr. Opin. Cell Biol. 13, 438-443 (2001). Abstract.
Lederkremer, G. Z., Cheng, Y., Petre, B. V., Vogan, E., Springer, S., Schekman, R., Walz, T., and Kirchhausen, T.
Structure of the Sec23p/24p and Sec13p/31p complexes of COPII. PNAS 98, 10704-10709 (2001). Abstract.
Matsuoka, K., Schekman, R., Orci, L., and Heuser, J.
Surface structure of the COPII-coated vesicle. PNAS 98, 13705-13709 (2001). Abstract.
Click here to see a list of older papers (1990-2000) from the Schekman lab.