Satoru Uzawa - Research Specialist 131 Koshland Hall Mailing Address: |
Research Summary |
I'm the microscopist of the lab. I maintain various microscopes and train new users. As my own challenge, I'm trying to measure dynamics of various components of dosage compensation complex of C. elegans by microscopy. |
Publications/Presentations |
Research Papers
Crane, E., Bian, Q., McCord, R.P., Lajoie, B.R., Wheeler, B. S., Ralston, E.J., Uzawa, S., Dekker, J., Meyer, B.J. (2015) Condensin-driven remodelling of X chromosome topology during dosage compensation. Nature, 1 June 2015 doi:10.1038/nature14450 [PDF] Libuda, D., Uzawa, S., Meyer, B.J., Villeneuve, A. (2013) Meiotic chromosome structures constrain and respond to designation of crossover sites. Nature 502, 703-706 (31 October 2013) [PDF] Shao L, Isaac B, Uzawa S, Agard DA, Sedat JW, Gustafsson MG. (2008). I5S: wide-field light microscopy with 100-nm-scale resolution in three dimensions. Biophys J. 94:4971-83 Jin Y, Mancuso JJ, Uzawa S, Cande WZ. (2005). The fission yeast homolog of the human transcription factor EAP30 blocks meiotic spindle pole body amplification. Developmental Cell 9 (1): 63-73 Tatebe, H; Shimada, K; Uzawa, S; Morigasaki, S; Shiozaki, K (2005). Wsh3/Tea4 Is a Novel Cell-End Factor Essential for Bipolar Distribution of Tea1 and Protects Cell Polarity under Environmental Stress in S. pombe. Curr Biol. 2005 15:1006-15. Uzawa S., Li F, Jin Y, McDonald K, Braunfeld M, Agard D, Cande WZ. (2004). Spindle pole body duplication in fission yeast occurs at the G1/S boundary but maturation is blocked until exit from S by an event downstream of cdc10 + . Molecular Biology of the Cell 15:5219 -5230 Sagolla, Meredith, Satoru Uzawa, W Zacheus Cande. (2003). Individual microtubule dynamics contribute to the function of mitotic and cytoplasmic arrays in fission yeast. J. Cell Sci. 116: 4891-4903 Francesca Zolezzi, Jill Fuss, Satoru Uzawa, and Stuart Linn. (2002). Characterization of a Schizosaccharomyces pombe Strain Deleted for a Sequence Homologue of the Human Damaged DNA Binding 1 (DDB1) Gene. J. Biol. Chem. 277: 41183-41191 Ye Jin, Satoru Uzawa, S and W. Zacheus Cande,. (2002). Fission yeast mutants affecting telomere clustering and meiosis-specific spindle pole body integrity. Genetics. 160(3):861-876. Pidoux, A. L., Uzawa, S., Perry, P., Cande, W. Z., and R. C. Allshire. (2000). Live analysis of lagging chromosome behaviour during anaphase and their effect on spindle elongation rate in fission yeast. J. Cell Sci. 113:4177-4191. Azuma, Y., Seino, H., Seki, T., Uzawa, S., Klebe, C., Ohba, T., Wittinghofer, A., Hayashi, N. and Nishimoto, T. (1996). Conserved histidine residues of RCC1 are essential for nucleotide exchange on Ran. J. Biochem. 120:82-01 Funabiki, H., Hagan, I., Uzawa, S. and Yanagida, M. (1993) Cell cycle-dependent specific positioning and clustering of centromeres and telomeres in fission yeast. J. Cell Biol. 121: 961-976 Seino, H., Hisamoto, N., Uzawa, S., Sekiguchi, T. and Nishimoto, T. (1992) DNA-binding domain of RCC1 protein is not essential for coupling mitosis with DNA replication. J. Cell. Sci. 102: 393-400 Uzawa, S. and Yanagida, M. (1992) Visualization of centromeric and nucleolar DNA in fission yeast by fluorescence in situ hybridization. J. Cell Sci. 101: 267-275 Horio, T., Uzawa, S., Jung, M.K., Oakley, B.R., Tanaka, K. and Yanagida, M. (1991) The fission yeast g-tubulin gene is essential for mitosis and localized at microtubule organizing centers. J. Cell Sci. 99: 693-700 Uzawa, S., Samejima, I., Hirano, T., Tanaka, K. and Yanagida, M. (1990) The fission yeast cut1 + gene regulates spindle pole body duplication and has homology to the budding yeast ESP1 gene. Cell 62: 913-925 Uemura, T., Morino, K., Uzawa, S., Shiozaki, K. and Yanagida, M. (1987) Cloning and sequencing of Schizosaccharomyces pombe DNA topoisomerase I gene, and effect of gene disruption. Nuc. Acids Res. 15: 9727-9739 Review Papers Nishimoto, T., Uzawa, S. and Schlegel, R. (1992) Mitotic checkpoints. Curr. Opinions in Cell Biol. 4: 174-179 Horio, T., Uzawa, S. , Toda, T., Oakley, BR. and Yanagida, M. (1990). Isolation of microtubule regulating factors from fission yeast. Cell Struc. Func. 15:476 |
Education |
1986 - 1988 Kyoto University, Kyoto, Japan Doctor of Philosophy in Biology 1980 - 1986 |