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Tomkinson, A. E., Bonk, R. T., Kim, J., Bartfeld, N. and Linn, S. (1990). Mammalian Mitochondrial Endonuclease Activities Specific for Ultraviolet-Irradiated DNA. Nuc. Acids Res. 18, 929-935.

Syvaoja, J., Soumensaari, S., Nishida, C., Goldsmith, J. S., Chui, G. S. J., Jain, S., and Linn, S. (1990). DNA Polymerases alpha, delta and epsilon: Three Distinct Enzymes from HeLa Cells. Proc. Nat'l. Acad. Sci. USA 87, 6664-6668.

Linn, S. (1991). How Many Pols Does it Take to Replicate Nuclear DNA? Cell 66, 185-187.

Keeney, S., Wein, H., and Linn, S. (1992). Biochemical Heterogeneity in Xeroderma Pigmentosum Complementation Group E. Mut. Res. 273, 49-56.

Ruscitti, T., Polayes, D. A., Karu, A. E., and Linn, S. (1992). Selective Immunoneutralization of Multiple Activities of Escherichia coli DNA Polymerase I Supports the Model for Separate Active Sites and Indicates a Complex 5' to 3' Exonuclease. J. Biol. Chem. 267, 16806-16811.

Ruscitti, T. and Linn, S. (1992). DNA Polymerase I Modulates Stable DNA Replication in Escherichia coli. J. Bacteriol. 174, 6311-6313.

Luo, Y., Henle, E. S., Chattopadhyaya, R., Jin, R., and Linn, S. (1994). Detecting DNA Damage Caused by Iron/Hydrogen Peroxide. In: Methods in Enzymology, Academic Press, NY, Vol. 234, pp. 51-59.

Keeney, S., Chang, G. J., and Linn, S. (1993). Characterization of a Human DNA Damage Binding Protein Implicated in Xeroderma Pigmentosum E. J. Biol. Chem. 268, 21293-21300.

Reardon, J. T., Nichols, A. F., Keeney, S., Smith, C. A., Taylor, J.-S., Linn, S., and Sancar, A. (1993). Comparative Analysis of Binding of Human XPE-DDB and Escherichia coli UvrA Damage Recognition Proteins to the Major UV Photoproducts: T[c,s]T, T[t,s]T, T[6-4]T, and T[Dew]T. J. Biol. Chem. 268, 21301-21308.

Linn, S., Lloyd, R. S., and Roberts, R. J., eds. (1993). Nucleases, Second Edition, Cold Spring Harbor Press, New York.

Linn, S. and Deutscher, M. P. (1993). The Nucleases of Escherichia coli. In: Nucleases, Second Edition (S. Linn, R. S. Lloyd, and R. J. Roberts, eds.), Cold Spring Harbor Press, New York, pp. 455-468.

Lloyd, R. S. and Linn, S. (1993). Nucleases involved in DNA Repair. In: Nucleases, Second Edition (S. Linn, R. S. Lloyd, and R. J. Roberts, eds.), Cold Spring Harbor Press, New York, pp. 263-316.

Luo, Y.-Z., Chin, S. M., and Linn, S. (1994). Three Chemically Distinct Types of Oxidants Formed by Iron-mediated Fenton Reactions in the Presence of DNA. Proc. Natl. Acad. Sci. USA 91, 12438-12442.

Keeney, S., Eker, A. P. M., Brody, T., Vermeulen, W., Bootsma, D., Hoeijmakers, J. H. J., and Linn, S. (1994). Correction of the DNA repair defect in xeroderma pigmentosum group E by injection of a DNA damage binding protein. Proc. Natl. Acad. Sci. USA 91, 4053-4056.

Chui, G. S. J. and Linn, S. (1994). Purification of Mammalian Polymerases epsilon. In: Methods in Enzymology, Vol. 262, Academic Press, New York pp. 93-98.

Chui, G. and Linn, S. (1995). Further Characterization of HeLa DNA Polymerase e. J. Biol. Chem. 270, 7799-7808.

Jessberger, R., Chui, G., Linn, S., and Kemper, B. (1996). Analysis of the Mammalian Recombination Protein Complex. Mut. Res. 350, 217-227.

Higuchi, Y. and Linn, S. (1995). Purification of All Forms of HeLa Cell Mitochondrial DNA and Assessment of Damage to It Caused by Hydrogen Peroxide Treatment of Mitochondria or Cells. J. Biol. Chem. 270, 7950-7956.

Rather, B. L., Chubatsu, L. S., and Linn, S. (1994). Comparison of ribosomal protein S3 from normal human fibroblasts to that from xeroderma pigmentosum - complementation group D(XP-D) fibroblasts. GenBank Accession Numbers U14990, U14991, U14992.

Dualan, R., Brody, T., Keeney, S., Nichols, A. F., Admon, A., and Linn, S. (1995). Chromosomal Localization and cDNA Cloning of the Genes (DDB1 and DDB2) for the p127 and p48 Subunits of a Human Damage-Specific DNA Binding Protein. Genomics 29, 62-69.

Kazantsev, A., Mu, D., Nichols, A. F., Zhao, X., Linn, S., and Sancar, A. (1996). Functional Complementation of Xeroderma Pigmentosum Group E by Replication Protein A (RPA) In an In Vitro System. Proc. Natl. Acad. Sci. U.S.A., 93, 5014-5018.

Maldonado, E., Shiekhattar, R., Sheldon, M., Cho, H., Drapkin, R., Rickert, P., Lees, E., Anderson, C. W., Linn, S., and Reinberg, D. (1996). A Human RNA Polymerase II Complex is Associated with Components Required for Transcriptional Activation and DNA Repair. Nature 381, 86-89.

Vaisman, A., Keeney, S., Nichols, A. F., Linn, S., and Chaney, S. G. (1996). Cisplatin- Induced Alterations in the Expression of the mRNAs for UV-Damage Recognition Protein. Oncology Research 8, 7-12.

Luo, Y., Henle, E. S., and Linn, S. (1996). Oxidative Damage to DNA Constituents by Iron- Mediated Fenton Reactions: The Deoxycytidine Family. J. Biol. Chem. 271, 21167-21176. abstract

Henle, E. S., Luo, Y., Gassman, W., and Linn, S. (1996). Oxidative Damage to DNA Constituents by Iron-Mediated Fenton Reactions: The Deoxyguanosine Family. J. Biol. Chem. 271, 21177-21186. abstract

Henle, E. S., Luo, Y., and Linn, S. (1996). Fe2+, Fe3+ and Oxygen React with DNA-Derived Radicals Formed During Iron-Mediated Fenton Reactions. Biochemistry 35, 12212-12219. abstract

Nichols, A. F., Ong, P., and Linn, S. (1996). Mutations Accompanying the Xeroderms Pigmentosum Group E Ddb- Phenotype. J. Biol. Chem. 271, 24317-24320. abstract

Linn, S. (1998). DNA Damage by Iron and Hydrogen Peroxide in Vitro and in Vivo. Drug Metabolism Reviews 30, 313-326.

Li, Y. Asahara, H., Patel, V., Zhou, S. and Linn, S. (1997). Purification, cDNA Cloning and Gene Mapping of the Small Subunit of Human DNA Polymerase Epsilon. J. Biol. Chem. 272, 32337-32344. abstract

Henle, E. S., Han, Z., Tang, N., Rai, P., Luo, Y., and Linn, S. (1999). Sequence-specific DNA Cleavage by Fe2+-mediated Fenton Reactions has Possible Biological Implications. J. Biol. Chem. 274, 962-971. abstract

Shiyanov, P., Hayes, S. A., Donepudi, M., Nichols, A. F., Linn, S., Slagle, B. L., and Raychaudhuri, P. (1999). The Naturally Occurring Mutants of DDB are Impaired in Stimulating Nuclear Import of the p125 Subunit and E2F1-Activated Transcription. Mol.Cell. Biol. 19, 4935- 4943. abstract

Zolezzi, F. and Linn, S. (2000). Studies of the murine DDB1 and DDB2 genes. Gene 245, 151- 159. abstract

Itoh, T., Linn, S., Ono, T., and Yamaizumi, M. (2000). Reinvestigation of the Classification of Five Cell Strains of Xeroderma Pigmentosum Group E with Reclassification of Three of Them. J. Invest. Derm. 114, 1022-1029. abstract

Nichols, A. F., Itoh, T., Graham, J. A., Liu, W., Yamaizumi, M., and Linn, S. (2000). Human Damage-specific DNA Binding Protein p48: Characterization of XPE Mutations and Regulation Following UV-irradiation. J. Biol. Chem. 275, 21422-21428. abstract

Liu, W., Nichols, A. F., Graham, J. A., Dualan, R., Abbas, A., and Linn, S. (2000). Nuclear Transport of Human DDB Protein Induced by Ultraviolet Light. J. Biol. Chem. 275, 21429- 21434. abstract

Li, Y., Pursell, Z. F., and Linn, S. (2000). Identification and Cloning of Two Histone-fold Motif Containing Subunits of HeLa DNA Polymerase epsilon. J. Biol. Chem. 275, 23247-23252. abstract

Itoh, T., Linn, S., Kamide, R., Tokushige, H., Katori, N., Hosaka, Y., Ono, T., and Yamaizumi, M. (2000). Xeroderma pigmentosum variant heterozygotes show reduced levels of recovery of replicative DNA synthesis in the presence of caffeine after ultraviolet light irradiation. J. Invest. Derm. 115, 981-985. abstract

Vlatkovic, N., Guerrera, S., Li, Y., Linn, S., Haines, D. S. and Boyd, M. T. (2000). MDM2 interacts with the carboxy terminus of the catalytic subunit of DNA polymerase Epsilon. Nuc. Ac. Res.28, 3581-3586. abstract

Liu, W. and Linn, S. (2000). Proteolysis of the human DNA polymerase epsilon catalytic subunit by caspase-3 and calpain specifically during apoptosis. Nuc. Ac. Res. 28, 4180-4188. abstract

Mizushina, Y., Kamisuki, S., Mizuno, T., Takemura, M., Asahara, H., Linn, S., Yamaguchi, T., Matsukage, A., Hanaoka, F., Yoshida, S., Saneyoshi, M., Sugawara, F., and Sakaguchi, K. (2000). Dehydroaltenusin: A mammalian DNA polymerase alpha inhibitor. J. Biol. Chem. 275, 33957-33961. abstract

Wakasugi, M., Shimizu, M., Morioka, H., Linn, S., Nikaido, O., and Matsunaga, T. (2001). Damaged DNA-binding protein DDB Stimulates the Excision of Cyclobutane Pyrimidine Dimers in Vitro in Concert with XPA and Replication Protein A. J. Biol. Chem. 276, 15434-15440. abstract pdf

Takemura, M., Yamamoto, T., Kitagawa, M., Taya, Y., Akiyama, T., Asahara, H., Linn, S., Suzuki, S., Tamai, K., and Yoshida, S. (2001). Stimulation of DNA Polymerase alpha Activity by Cdk2-Phosphorylated Rb Protein. Biochem. Biophys. Res. Comm. 282, 984-990. abstract pdf

Abbas, A. R., and Linn, S. (2001). Homo sapiens polymerase (DNA directed) theta (Pol Q) mRNA. Genbank accession number AYO32677.

Itoh, T., Nichols, A., and Linn, S. (2001). Abnormal Regulation of DDB2 Gene Expression in Xeroderma Pigmentosum Group E Strains. Oncogene 20, 7041-7050. abstract

Rai, P., Cole, T. D., Wemmer, D. E., and Linn, S. (2001). Localization of Fe2+ at an RTGR Sequence within a DNA duplex explains preferential cleavage by Fe2+ and H202. J. Mol. Biol. 312, 1089-1101. abstract

Itoh, T. and Linn, S. (2001). XP43TO, Previously classified as Xeroderma Pigmentosum Group E, should be reclassified as Xeroderma Pigmentosum Variant. J. Invest. Derm., 117, 1672-1674. full text

Wakasugi, M., Kawashima, A., Morioka, H., Linn, S., Sancar, A., Mori, T., Nikaido, O., and Matsunaga, T. (2002). DDB accumulates at DNA damage sites immediately after UV irradiation and directly stimulates nucleotide excision repair. J. Biol. Chem. 277, 1637-1640. full text

Mizushina, Y., Kamisuki, S., Kasai, N., Shimazaki, N., Takemura, M., Asahara, H., Linn, S., Yoshida, S., Matsukage, A., Koiwai, O., Sugawara, F., Yoshida, H., and Sakaguchi, K. (2002). A plant phytotoxin, solanapyrone A, is an inhibitor of DNA polymerase b and l. J. Biol. Chem. 277, 630-638. full text

Murakami, C., Takemura, M., Sugiyama, Y., Kamisuki, S., Asahara, H., Kawasaki, M., Ishidoh, T., Linn, S., Yoshida, S., Sugawara, F., Yoshida, H., Sakaguchi, K., and Mizushina, Y. (2002). Vitamin A-related compounds, all-trans retinal and retinoic acids, selectively inhibit activities of mammalian replicative DNA polymerases. Biochim. Biophys. Acta 1574, 85-92. abstract

Fuss, J. and Linn, S. (2002). Human DNA polymerase epsilon colocalizes with DNA replication late, but not early in S phase. J. Biol. Chem. 277, 8658-8666. full text

Zolezzi, F., Fuss, J., Uzawa, S. and Linn, S. (2002). Characterization of a Schizosaccharomyces Pombe Strain Deleted for a Sequence Homologue of the Human Damaged DNA Binding 1 (DDB1) Gene. J. Biol. Chem. 277, 41183-41191. full text

Mizushina, Y., Kamisuki, S., Kasai, N., Ishidoh, T., Shimazuki, N., Takemure, M., Asahara, H., Linn, S., Yoshida, S., Koiwai, O., Sugawara, F., Yoshida, H., and Sakaguchi, K. (2002). Petasiphenol: A DNA Polymerase l inhibitor. Biochemistry 41, 14463-14471. full text

Nichols, A. F., Itoh, T., Zolezzi, F., Hutsell, S., and Linn, S. (2003). Basal transcriptional activation of human damage-specific DNA binding genes DDB1 and DDB2 by sp1, E2F, N-MYC and NF1 elements. Nuc. Ac. Res. 31, 562-569. full text

Mizushina, Y., Xu, Xianai, Asahara, H., Takeuchi, R., Oshige, M., Shimazaki, N., Takemura, M., Yamaguchi, T., Kuroda, K., Linn, S., Yoshida, H., Koiwai, O., Saneyoshi, M., Sugawara, F., and Sakaguchi, K. (2003). A sulfoquinovosyl diacylglycerol is a DNA polymerase epsilon inhibitor. Biochem. J. 370, 299-305. full text

Asahara, H., Li, Y., Fuss, J., Hanes, D. S. Vlatkovic, N., Boyd, M. T., and Linn, S. (2002). Stimulation of Human DNA Polymerase epsilon by MDM2. Nuc. Ac. Res. 31, 2323-2332. full text

Rai, P., Cole, T.D., Thompson, E., Millar, D., and Linn, S. (2003). Steady-state and time-resolved fluorescence studies indicate an unusual conformation of 2-aminopurine within ATAT and TATA duplex sequences. Nuc. Ac. Res. 31, 2451-2459. full text

Mizushina, Y., Xu, X., Asano, N., Kasai, N., Kato, A., Takemura, M., Asahara, H., Linn, S., Sugawara, F., Yoshida, H., and Sakaguchi, K. (2003). The inhibitory action of pyrrolidine alkaloid, 1-4-dideoxy-1,4-immino-D-ribitol, on eukaryotic DNA polymerases. Bioch. Biophys. Res. Comm. 304, 78-85. full text

Sancar, A., Lindsey-Boltz, L. A., Unsal-Kacmaz, K. and Linn, S. M. (2004). Molecular Mechanisms of Mammalian DNA Repair and the DNA Damage Checkpoints. Ann. Rev. Bioch. 73, 39-85.

Itoh, T., O'Shea, C. and Linn, S. (2003). Impaired Regulation of Tumor Suppressor p53 Caused by Mutations in the Xeroderma Pigmentosum DDB2 Gene: Mutual Regulatory Interactions between p48DDB2 and p53. Mol. Cell. Biol. 23, 7540-7553. full text

Brumaghim, J. L., Li, Y., Henle, E. and Linn, S. (2003). Effects of Hydrogen Peroxide upon Pyridine Nucleotide Metabolism in Escherichia coli: changes in Enzyme Levels and Pyridine Nucleotide Pools and Studies of the Oxidation of NAD(P)H by Fe(III). J. Biol. Chem. 278, 42495-42504. full text

Itoh, T., Cado, D., Kamide, R., and Linn, S. (2004). DDB2 gene disruption leads to skin tumors and resistance to apoptosis after exposure to ultraviolet light but not a chemical carcinogen. Proc. Nat'l. Acad. Sci. USA 101, 2052-2057. full text

Rai, P., Wemmer, D.E. and Linn, S. (2005). Preferential binding and structural distortion by Fe2+ at RGGG-containing DNA sequences correlates with enhanced oxidataive cleavage at such sequences. Nuc. Acids Res. 33, 497-510. full text

Itoh, T. and Linn, S. (2005). The fate of p21CDKNIA in cells surviving UV-irradiation. DNA Repair 4, 1457-1462. full text