Developmental Cell Journal Club

Developmental Cell Journal Club

Date	Moderator	Topic	Paper(s)
11/23/09	Jen-Yi Lee	Myosin II Tension Cables & Morphogenesis	Myosin II Dynamics Are Regulated by Tension in Intercalating Cells Fernandez-Gonzalez et al. Dev Cell 17(5):736-743 (2009)
5/18/09	Sara Peyrot	PCP, Hedgehog, and Ciliogenesis	Ciliogenesis defects in embryos lacking inturned or fuzzy function are associated with failure of planar cell polarity and Hedgehog signaling Park et al. Nature Genetics 38(3):303-311 (2006) Dishevelled controls apical docking and planar polarization of basal bodies in ciliated epithelial cells. Park et al. Nature Genetics 40(7):871-879 (2008)
4/20/09	David Weisblat	Myosin, actin, and the spindle	Myosin-10 and actin filaments are essential for mitotic spindle function. Wooler et al., Journal of Cell Biology 182:77-88. (2008)
2/2/09	Jen-Yi Lee	Endocytosis and membrane remodeling during development.	Local Actin-Dependent Endocytosis is Zygotically Controlled to Initiate Drosophila Cellularization. Sokac and Wieschaus, Dev Cell 14, 775-786. (2008)
12/8/08	Isabelle Philipp	Molecular mechanisms of vertebrate cardiovascular differentiation.	MesP1 drives vertebrate cardiovascular differentiation through Dkk-1-mediated blockade of Wnt-signalling David et al., Nature Cell Biology 10(3): 338-345. (2008) The Origins of Cardiac Tissue in the Amphibian, Xenopus laevis Mohun et al., Trends Cardiovasc Med 13:244–248. (2003)
11/17/08	Lucy O'Brien	Stem cell karma and tissue reincarnation: Adaptive homeostasis during organ self-renewal	JNK Activity in Somatic Stem Cells Causes Loss of Tissue Homeostasis in the Aging Drosophila Gut Biteau et al., Cell Stem Cell 3, 442-455. (2008)
10/27/08	Saori Haigo	Are polarized cell-matrix interactions controlling polarized cell intercalation to shape the Drosophila egg?	Multicellular Rosette Formation Links Planar Cell Polarity to Tissue Morphogenesis Blankenship et al., Developmental Cell 11, 459–470. (2006)
10/6/08	Jen-Yi Lee	(recent papers of interest)	Apoptotic force and tissue dynamics during Drosophila embryogenesis. Toyama et al., Science 19;321(5896):1683-6. (2008) Ryk cooperates with Frizzled 7 to promote Wnt11-mediated endocytosis and is essential for Xenopus laevis convergent extension movements. Kim et al., J Cell Bio 182(6):1073-82. (2008)
6/16/08	Dian-Han Kuo	Some curious cell behaviors in early leech embryogenesis: is actin cytoskeleton regulation by SMAD-independent TGFbeta signaling involved?	LIM-kinase 2 and cofilin phosphorylation mediated actin cytoskeleton reorganization induced by transforming growth factor-b. Vardouli et al., J Biol Chem 280, 11448-11457. (2005) Cofilin activity downstream of Pak1 regulates cell protrusion efficiency by organizing lamellipodium and lamella actin networks. Delorme et al., Dev Cell 13, 646-662. (2007)
5/19/08	Weiyang Shi	Directional cell movement: signals from outside and within	The Bmp Gradient of the Zebrafish Gastrula Guides Migrating Lateral Cells by Regulating Cell-Cell Adhesion von der Hardt et al., Curr Biol 17, 475-487. (2007) Wnt5a Control of Cell Polarity and Directional Movement by Polarize Redistribution of Adhesion Receptors Witze et al., Science 320, 365-369. (2008)
3/31/08	Saori Haigo	How does a polarized extracellular matrix control the elliptical shape of the Drosophila egg?	Viscoelastic Retraction of Single Living Stress Fibers and Its Impact on Cell Shape, Cytoskeletal Organization, and Extracellular Matrix Mechanics Kumar et al., Biophysical Journal 90: 3762–3773. (2006) Integrin a5b1 and Fibronectin Regulate Polarized Cell Protrusions Required for Xenopus Convergence and Extension Davidson et al., Curr Biol 16: 833–844. (2006)
2/25/08	Dede Lyons	Cortex-microtubule interactions controlling asymmetrical cell division.	Numb Controls Integrin Endocytosis for Directional Cell Migration with aPKC and PAR-3 Nishimura and Kozo Kaibuchi, Dev Cell 13: 15-28. (2007) Akt regulates centrosome migration and spindle orientation in the early Drosophila melanogaster embryo Buttrick et al., J Cell Biol 180(3):537-48. (2008)
1/14/08	Jen-Yi Lee	What is the function of endocytosis during Xenopus bottle cell apical constriction?	Endosomal recycling controls plasma membrane area during mitosis Boucrot and Kirchhausen, PNAS 104, 7939–7944. (2007) The FERM Protein Yurt Is a Negative Regulatory Component of the Crumbs Complex that Controls Epithelial Polarity and Apical Membrane Size Laprise et al., Developmental Cell 11, 363–374. (2006)
12/10/07	Lionel Christiaen	Does RhoDF control filopodia merging in Ciona migrating heart precursors?	RhoD regulates endosome dynamics through Diaphanous-related Formin and Src tyrosine kinase. Gasman et al., Nature Cell Biology 5, 195-204. (2003) Microtubule-targeting-dependent reorganization of filopodia. Schober et al., Journal of Cell Science 120, 1235-1244. (2007)

General Info:

Who we are: Researchers in the UC Berkeley Molecular & Cell Biology Department who are interested in the interface between Cell and Developmental Biology

When/where we meet: Once a month, Mondays at noon. 547 LSA. Bring your lunch!

What's the format? One person picks a paper or discusses their own research (informally), and moderates ACTIVE discussion amongst all participants.

What do we talk about? The plan is for the group to be user-friendly. That is, those who show up will determine the topics covered. Some possible topics include:

Cell polarity
Cell cycle
Morphogenesis
Cell migration
Cell signaling
Transcription and cell biology
New techniques and reagents for studying cell biology in living organisms

Contact:

Want to join our listserv? Send blank e-mail to: dev_cell_bio_jc-join@lists.berkeley.edu

Questions? Please email Jen-Yi Lee (Harland Lab)