Selected Publications

• Altered modes of stem cell division drive adaptive intestinal growth O'Brien LE, Soliman SS, Li X, Bilder D. Cell. 2011 Oct 28;147(3):603-14.
• Global Tissue Revolutions in a Morphogenetic Movement Controlling Elongation Haigo SL, Bilder D Science, 2011,Feb 25:331(6020):1071-4
• Endocytic internalization routes required for Delta/Notch signaling Windler S, Bilder D Current Biology 2010, Mar 23;20(6):538-43.
• The vacuolar ATPase is required for physiological as well as pathological Notch signaling activation Vaccari T, Bilder D Development 2010, Jun:137(11):1825-32.
• Polarity and endocytosis: reciprocal regulation. Shivas JM, Morrison HA, Bilder D, Skop A. Trends in Cell Biology 2010, Aug:20(8):445-52.
• A tumor suppressive activity of Drosophila Polycomb genes mediated by JAK/STAT signaling. Classen AK, Bunker BD, Harvey KF, Vaccari T, Bilder D. Nature Genetics 2009, Oct;41(10):1150-5.
• Endocytic regulation of Notch signaling. Fortini ME, Bilder D. Current Opinion in Genetetics and Development. 2009 Aug;19(4):323-8.
• Comparative analysis of ESCRT-I, ESCRT-II and ESCRT-III function in Drosophila by efficient isolation of ESCRT mutants. Vaccari T, Rusten TE, Menut L, Nezis IP, Brech A, Stenmark H, Bilder D. Journal of Cell Science. 2009 Jul 15;122(Pt 14):2413-23
• Regulation of early endosomal entry by the Drosophila tumor suppressors Rabenosyn and Vps45. Morrison HA, Dionne H, Rusten TE, Brech A, Fisher WW, Pfeiffer BD, Celniker SE, Stenmark H, Bilder D. Molecular Biology of the Cell. 2008 Oct;19(10):4167-76.
• Endosomal entry regulates Notch receptor activation in Drosophila melanogaster. Vaccari T, Lu H, Kanwar R, Fortini ME, Bilder D Journal of Cell Biology 2008 Feb 25;180(4):755-62.
• Dynein regulates epithelial polarity and the apical localization of stardust A mRNA. Horne-Badovinac S, Bilder D PLoS Genetics 2008 Jan;4(1):e8.
• A mosaic genetic screen for Drosophila neoplastic tumor suppressor genes based on defective pupation. Menut L, Vaccari T, Dionne H, Hill J, Wu G, Bilder D Genetics 2007 Nov;177(3):1667-77.
• Regulation of imaginal disc growth by tumor-suppressor genes in Drosophila. Hariharan IK, Bilder D Annual Review of Genetics 2006 Vol. 40:335-61.
• Endocytic control of epithelial polarity and proliferation in Drosophila. Lu H, Bilder D Nature Cell Biology 2005 Oct; 232(3):559-74.
• The Drosophila Tumor Suppressor vps25 Prevents Nonautonomous Overproliferation by Regulating Notch Trafficking. Vaccari T, Bilder D Developmental Cell 2005 Nov; 9(5):687-98.
• Mass transit: epithelial morphogenesis in the Drosophila egg chamber. Horne-Badovinac S, Bilder D Developmental Dynamics 2005 Mar; 232(3):559-74.
• Domains controlling cell polarity and proliferation in the Drosophila tumor suppressor Scribble. Zeitler J, Hsu CP, Dionne H, Bilder D Journal of Cell Biology 2004 Dec 20;167(6):1137-46.
• Epithelial polarity and proliferation control: links from the Drosophila neoplastic tumor suppressors. Bilder D Genes and Development 2004 Aug 15;18(16):1909-25.
• Integrated activity of PDZ protein complexes mediates the maturation of epithelial polarity. Bilder D, Schober M, Perrimon N Nature Cell Biology 2003 Jan; 5(1):53-8.
• Polarity determination in breast tissue: desmosomal adhesion, myoepithelial cells, and laminin 1. Bissell MJ, Bilder D Breast Cancer Research 2003 5(2):117-9.
• Recruitment of Scribble to the synaptic scaffolding complex requires GUK-holder, a novel DLG binding protein. Mathew D, Gramates LS, Packard M, Thomas U, Bilder D, Perrimon N, Gorczyca M, Budnik V Current Biology 2002 12 :531-9.
• PDZ proteins and polarity: functions from the fly. Bilder D Trends in Genetics 2001 17 : 511-8.
• Cell polarity: squaring the circle. Bilder D Current Biology 2001 11 (4):R132-5.
• Cooperative regulation of cell polarity and growth by Drosophila tumor suppressors. Bilder D, Li M, Perrimon N Science 2000 289 (5476): 113-6.
• Collective nomenclature for LAP proteins. Bilder D, Birnbaum D, Borg JP, Bryant P, Huigbretse J, Jansen E, Kennedy MB, Labouesse M, Legouis R, Mechler B, Perrimon N, Petit M, Sinha P Nature Cell Biology 2000 2(7): E114.
• Localization of apical epithelial determinants by the basolateral PDZ protein Scribble. Bilder D, Perrimon N Nature 2000 403 (6770): 676-80. cf comment in Nature 403:611-2.