Publications:

Barbalat R, Lau L, Locksley RM, Barton GM. Toll-like receptor 2 on inflammatory monocytes induces type I interferon in response to viral but not bacterial ligands, Nature Immunology in press.


Barton GM, Kagan JC. A cell biological view of Toll-like receptor function: regulation through compartmentalization, Nature Reviews Immunology (2009) 9, 535-542


Ewald SE, Lee BL, Lau L, Wickliffe KE, Shi GP, Chapman HA, Barton GM. The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor, Nature (2008) 456: 658-662.

Sokol CL, Barton GM, Farr AG, Medzhitov R. A mechanism for the initiation of allergen-induced T helper type 2 responses, Nature Immunology (2008) 9: 310-318.

Barton GM. A calculated response: control of inflammation by the innate immune system, J. Clin. Invest. (2008) 118: 413-420.

Barton GM. Viral recognition by Toll-like receptors, Semin Immunol. (2007) 19:33-40.

Barton GM, Kagan JC, Medzhitov R. Intracellular localization of Toll-like receptor 9 prevents recognition of self DNA but facilitates access to viral DNA, Nat Immunol. (2006) 7:49-56.

Horng T, Barton GM, Flavell RA, Medzhitov R. The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors, Nature. (2002) 420:329-33.

Schnare M, Barton GM, Holt AC, Takeda K, Akira S, Medzhitov R. Toll-like receptors control activation of adaptive immune responses, Nat Immunol (2001) 10:947-50.

Horng T, Barton GM, Medzhitov R. TIRAP: an adaptor in the Toll signaling pathway, Nat Immunol. (2001) 2:835-841.