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Publications:
Mouchess ML, Arpaia N, Souza G, Barbalat R, Ewald SE, Lau L, Barton GM. Transmembrane Mutations in Toll-like Receptor 9 Bypass the Requirement for Ectodomain Proteolysis and Induce Fatal Inflammation, Immunity (2011) 35: 1-12.
Zanoni I, Ostuni R, Marek LR, Barresi S, Barbalat R, Barton GM, Granucci F, Kagan JC. CD14 Controls the LPS-Induced Endocytosis of Toll-like Receptor 4, Cell (2011) 147: 868-880.
Arpaia N, Barton GM. Toll-like receptors: key players in antiviral immunity, Current Opinion in Virology (2011) 1:1-8.
Barbalat R, Ewald SE, Mouchess ML, Barton GM. Nucleic Acid Recognition by the Innate Immune System, Annual Review of Immunology (2011) 29: 185-214.
Ewald SE, Engel A, Lee J, Wang M, Bogyo M, Barton GM. Nucleic acid recognition by Toll-like receptors is coupled to stepwise processing by cathepsins and asparagine endopeptidase, Journal of Experimental Medicine (2011) 208: 643-651.
Arpaia N, Godec J, Lau L, Sivick KE, McLaughlin LM, Jones MB, Dracheva T, Peterson SN, Monack DM, Barton GM. TLR signaling is required for Salmonella typimurium virulence, Cell (2011) 144: 675-688.
Video abstract can be found here.
Barbalat R, Lau L, Locksley RM, Barton GM. Toll-like receptor 2 on inflammatory monocytes induces type I interferon in response to viral but not bacterial ligands, Nature Immunology (2009) 10: 1200-1207.
Barton GM, Kagan JC. A cell biological view of Toll-like receptor function: regulation through compartmentalization, Nature Reviews Immunology (2009) 9: 535-542
Ewald SE, Lee BL, Lau L, Wickliffe KE, Shi GP, Chapman HA, Barton GM. The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor, Nature (2008) 456: 658-662.
Barton GM. A calculated response: control of inflammation by the innate immune system, J. Clin. Invest. (2008) 118: 413-420.
Barton GM. Viral recognition by Toll-like receptors, Semin. Immunol. (2007) 19:33-40.
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