The following is an alphabetical list of MCB faculty members and brief descriptions of their research. A list of faculty by division affiliation is available here. Bowes fellows are at the bottom.
Tom Alber
Endowed Chair, Chancellor's Class of '43 Professor of Biochemistry, Biophysics and Structural Biology
Structure/function correlates in tuberculosis, HIV/AIDS, molecular recognition and signaling
Mark Alper
Adjunct Professor of Biochemistry, Biophysics and Structural Biology
Biochemistry; biomolecular materials
Bruce N. Ames
Professor of the Graduate School Division of Biochemistry, Biophysics and Structural Biology
Mechanisms of aging. Mitochondrial decay in aging. Oxidants and antioxidants in DNA damage. Micronutrient deficiencies and DNA damage. Chronic inflammation and Cancer.
Clinton E. Ballou
Professor Emeritus of Biochemistry, Biophysics and Structural Biology
James Berger
Professor of Biochemistry, Biophysics and Structural Biology
Structural and mechanistic biochemistry of macromolecular assemblies and machines that regulate the initiation of DNA replication and chromosome and superstructure
Carolyn R. Bertozzi
Howard Hughes Investigator and Professor of Biochemistry, Biophysics and Structural Biology
Molecular basis of cell surface interactions
Michael Botchan
Richard and Rhoda Goldman Distinguished Professorship in Biological Sciences Professor of Biochemistry, Biophysics and Structural Biology
Eukaryote DNA replication and control of S phase
Carlos Bustamante
Howard Hughes Investigator and Raymond and Beverly Sackler Chair and Professor of Biochemistry, Biophysics and Structural Biology
Structural characterization of nucleo-protein assemblies
Richard Calendar
Professor of the Graduate School Division of Biochemistry, Biophysics and Structural Biology
Molecular genetics of viruses
Jamie H. D. Cate
Associate Professor of Biochemistry, Biophysics and Structural Biology
Molecular Basis for Protein Synthesis by the Ribosome
Christopher Chang
Howard Hughes Investigator and Professor of Biochemistry, Biophysics and Structural Biology
Discovery and elucidation of new signal transduction players and pathways with molecular imaging
Michelle Chang
Assistant Professor of Biochemistry, Biophysics and Structural Biology
Enzyme catalysis and metabolic engineering
Kathleen Collins
Professor of Biochemistry, Biophysics and Structural Biology
Telomerase, non-coding RNAs, RNA silencing
Jennifer A. Doudna
Howard Hughes Investigator and Professor of Biochemistry, Biophysics and Structural Biology
RNA-mediated gene regulation
Peter Duesberg
Professor of Biochemistry, Biophysics and Structural Biology
Genetic structure of retroviruses
Robert Glaeser
Professor Emeritus of Biochemistry, Biophysics and Structural Biology
Cryo-EM of multiprotein complexes; membrane proteins; structural biology; biophysics; advancing the capabilities of high-resolution cryo-EM in biology.
Britt Glaunsinger
Associate Professor of Biochemistry, Biophysics and Structural Biology
Virology; messenger RNA processing and degradation
Alexander Glazer
Professor of the Graduate School Division of Biochemistry, Biophysics and Structural Biology
Macomolecular complexes; photosynthetic systems
Ming Hammond
Assistant Professor of Biochemistry, Biophysics and Structural Biology
Chemical Biology, Molecular Biology, Organic Chemistry, and Bioinformatics
Caroline Kane
Professor Emeritus of Biochemistry, Biophysics and Structural Biology
Eukaryotic gene regulation during transcript elongation
Jack Kirsch
Professor of the Graduate School Division of Biochemistry, Biophysics and Structural Biology
Enzymology; site-directed mutagenesis
Judith Klinman
Professor of the Graduate School Division of Biochemistry, Biophysics and Structural Biology
Principles of catalytic and regulatory mechanisms in enzyme-catalyzed reactions
Bryan A. Krantz
Assistant Professor of Biochemistry, Biophysics and Structural Biology
Molecular Mechanism of Protein Translocation Across Membranes
John Kuriyan
Howard Hughes Investigator and Chancellor's Professor of Biochemistry, Biophysics and Structural Biology
Structural and functional studies of signal transduction and DNA replication
Stuart Linn
Professor of the Graduate School Division of Biochemistry, Biophysics and Structural Biology
Enzymology of DNA metabolism
Michael Marletta
Aldo DeBenedictis Distinguished Professor of Chemistry and Professor of Biochemistry, Biophysics and Structural Biology
Structure/Function Relationships in Proteins; Enzyme Catalysis; Molecular Mechanisms of Cell Signaling
Susan Marqusee
Director of QB3 and Eveland Warren Endowed Chair Professor of Biochemistry, Biophysics and Structural Biology
Determinants of protein structure and folding
Andreas Martin
Assistant Professor of Biochemistry, Biophysics and Structural Biology
Energy-dependent proteases and molecular machines
Hiroshi Nikaido
Professor of the Graduate School Division of Biochemistry, Biophysics and Structural Biology
Membrane biochemistry; bacterial physiology
Eva Nogales
Howard Hughes Investigator and Professor of Biochemistry, Biophysics and Structural Biology
Structure-function of macromolecular assemblies: cytoskeleton self-assembly and nucleic acid transactions
Daniel Portnoy
Professor of Biochemistry, Biophysics and Structural Biology
Molecular and cellular basis of microbial pathogenesis
David Savage
Assistant Professor of Biochemistry, Biophysics and Structural Biology
Synthetic biology and metabolism.
Howard Schachman
Professor of the Graduate School Division of Biochemistry, Biophysics and Structural Biology
Physical biochemistry
Jeremy Thorner
Professor of Biochemistry, Biophysics and Structural Biology
Signal transduction mechanisms; biochemistry; molecular genetics; cell biology
Robert Tjian
Howard Hughes Investigator and Professor of Biochemistry, Biophysics and Structural Biology
Eukaryotic molecular biology; biochemistry
Ahmet Yildiz
Assistant Professor of Biochemistry, Biophysics and Structural Biology
Structural mechanism of molecular motors. High resolution imaging of subcellular structures
Qing Zhong
Assistant Professor of Biochemistry, Biophysics and Structural Biology
Mechanistic Studies of Apoptosis and Autophagy in Mammals
Qiang Zhou
Professor of Biochemistry, Biophysics and Structural Biology
Biochemistry of HIV gene expression and transcriptional elongation
David Zusman
Professor of the Graduate School Division of Biochemistry, Biophysics and Structural Biology
Microbial development; molecular genetics
The following faculty have a secondary affiliation with the Biochemistry, Biophysics and Structural Biology division.
Richard Harland
Department Co-Chair and C.H. Li Distinguished Professor Professor of Genetics, Genomics and Development
Molecular biology of development
G. Steven Martin
Dean of Biological Sciences and Professor of Cell and Developmental Biology
Cell biology; tumor virology
Michael Rape
Associate Professor of Cell and Developmental Biology
Protein ubiquitination, degradation and the control of cell division and differentiation
Donald Rio
Professor of Genetics, Genomics and Development
Molecular genetics; transposable elements; RNA splicing
Randy Schekman
Howard Hughes Investigator and Professor of Cell and Developmental Biology
Organelle assembly; protein transport
Mark Schlissel
Dean of Biological Sciences and Professor of Immunology and Pathogenesis
The regulation of lymphocyte development, genetic transcription, chromatin structure, and V(D)J recombination.
Liam Holt
Bowes Research Fellow
Evolution of cellular signaling systems, cell division control, synthetic biology
Liming Wang
Bowes Research Fellow
Identification of novel genetic and neural players in the regulation of energy homeostasis, and how they are involved in the pathogenesis of metabolic disorders
Woj Wojtowicz
Bowes Research Fellow
Molecular basis for neuronal cell recognition, axon guidance and synaptogenesis