Shown is a ribbon diagram of the crystal structure of XOL-1, the primary determinant of sexual fate in C. elegans.

Photo courtesy of Howard Hughes Investigator and Professor Barbara Meyer.

Oncogenically transformed cells (upper left) degrade a fluorescently-labeled substrate (green).

Photo courtesy of Professor G. Steven Martin.

Oncogenically transformed fibroblasts can assemble actin into ring-like invasive structures called podosomes, shown in green.

Photo courtesy of Professor G. Steven Martin.