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Lecture 1, Jan 20, Tu. Overview of principles I. (Chapters 1 and 5)
Lecture 2, Jan 22, Th. Overview of principles II.
Lecture 3, Jan 27, Tu. Drosophila embryogenesis. Dorsal-ventral patterning. (pg. 253-266, Chapter 9)
Lecture 4, Jan 29, Th. Segmentation I. (pg. 266-283, Chapter 9)
Lecture 5, Feb 3, Tu. Segmentation II.
Lecture 6, Feb 5, Th. Homeosis I. (pg. 283-290, Chapter 9, and Chapter 11 of Evolution [on reserve at Koshland Biosciences Library])
Lecture 7, Feb 10, Tu. Appendages.
Lecture 8, Feb 12, Th. Homeosis II.
Lecture 9, Feb 17, Tu. Review and summary.
Midterm I: Thursday Feb. 19 11:10-12:30. Rooms TBA.
II. Professor John Gerhart
Middle third of the course: early development of vertebrates to the late neurula stage
Click here for page numbers for the sixth edition of the textbook.
Lecture 11, Feb 24, Tu. Chordates and vertebrates: defining traits, outline of amphibian development, comparison to Drosophila (42-46; 216-217; 725-731; 742-744).
Lecture 12, Feb 26, Th. Amphibian development: fate maps; discovery of Spemann’s organizer. (10-13; 25-31; 57-62. 304-306.)
Lecture 13, Mar 03, Tu. Oogenesis; Cytoplasmic localizations in the amphibian egg (81-83; 136; 153-158; 615-619)
Lecture 14, Mar 05, Th. Cortical rotation and axis formation (291-294; 302-310)
Lecture 15, Mar 10, Tu. Endo-mesoderm induction (155-158; 311-312)
Lecture 16, Mar 12, Th. Formation of Spemann's organizer (312-324)
Lecture 17, Mar 17, Tu. Gastrulation (29; 295-302)
Lecture 18, Mar 19, Th. Neural induction and neurulation (312-324; 375-381)
Mar 24, Tu. Spring Break
Mar 26, Th. Spring Break
Lecture 19, Mar 31, Tu. Chick development, extraembryonic development (336-348; 501-503; 45)
Lecture 20, Apr 02, Th. Mammalian early development (92-96; 348-368)
Midterm 2: Tuesday, April 7, 11:10-12:30. Rooms TBA.
III. Professor Richard Harland
Final third of the course: late development of vertebrates--organogenesis, cytodifferentiation
Lecture 22, Apr 9, Th. Mammalian gastrulation
Lecture 23, Apr 14, Tu. Neurulation
Lecture 24, Apr 16, Th. Spinal cord
Lecture 25, Apr 21, Tu. Somites
Lecture 26, Apr 23, Th. The neural crest and placodes (lecture by Prof. Gerhart)
Lecture 27, Apr 28, Tu. Muscle and axial identity
Lecture 28, April 30, Th. The limb
Lecture 29, May 05, Tu. Axon guidance
Lecture 30, May 07, Th. Organogenesis of the kidney
Final Exam: Tuesday, May 19th, 8–11 AM.
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