Referenced Textbook (recommended, not required): Scott F. Gilbert, Developmental Biology, Ninth (2010) or Eighth Edition (2006)

I. Professor Nipam Patel

First third of the course: Dorso-ventral and antero-posterior patterning of Drosophila
Referenced Textbook (recommended, not required): Scott F. Gilbert, Developmental Biology, Ninth (2010) or Eighth Edition (2006)

Lecture 1, Jan 17, Tu. Overview of principles I. (Chapter 1, 2) (Chapters 1 and 5) "The Demise of Bill"  Pre-notes Complete lecture
Lecture 2, Jan 19, Th. Overview of principles II. Intro to Drosophila development. (pg. 188 - 192, Chapter 5) (pg. 239-242, Chapter 8) Pre-notes Complete lecture
Lecture 3, Jan 24, Tu. Drosophila embryogenesis. Dorsal-ventral patterning. (pg. 203-217, Chapter 6) (pg. 253-266, Chapter 9)  Pre-notes Complete lecture
Lecture 4, Jan 26, Th. Segmentation I. (pg. 218-233, Chapter 6) (pg. 266-283, Chapter 9) Pre-notes Complete lecture
Lecture 5, Jan 31, Tu. Segmentation II. Pre-notes Complete lecture
Lecture 6, Feb 2, Th. Homeosis I. (pg. 234-239, Chapter 6) (pg. 283-290, Chapter 9) AND Chapter 11 of Evolution -> on reserve at Koshland Biosciences Library] Pre-notes Complete lecture
Lecture 7, Feb 7, Tu. Homeosis II Pre-notes Complete lecture
Lecture 8, Feb 9, Th. Wing Patterning and Review and Summary. Pre-notes Complete lecture and REVIEW

Midterm I: Feb. 14 Tu. 11:10-12:30. Room 3108 ETCHEVERRY.

 

II. Professor John Gerhart

Middle third of the course: Early development of vertebrates through the neurula stage.
Referenced Textbook (recommended, not required): Scott F. Gilbert, Developmental Biology, Ninth (2010) or Eighth Edition (2006)

Lecture 1, Feb 16, Th. Chordates and vertebrates: defining traits, outline of amphibian development 6-11 (42-46; 216-217; 722; 725-731; 742-744)  PPT_slides Movie1 Movie2 Lecture notes
Lecture 2, Feb 21, Tu. Fate, competence, specification, determination. Discovery of Spemann’s organizer. 19-21; 112-113; 241-244; 255-256 (10-13; 25-31; 57-62. 304-306)    PPT_slides Lecture notes
Lecture 3, Feb 23, Th. Cytoplasmic localizations, cortical rotation, and axis formation in the amphibian egg 92-93; 242-244 (81-83; 136; 153-158; 615-619 and 291-294; 302-310). PPT_slides Lecture notes
Lecture 4, Feb 28, Tu. Endo-mesoderm induction 94-95; 257-262 (155-158; 311-312). PPT_slides Lecture notes
Lecture 5, Mar 1, Th. Formation of Spemann's organizer 261-263 (312-324). PPT_slides Lecture notes
Lecture 6, Mar 6, Tu. Gastrulation 9; 244-252 (29; 295-302). PPT_slides / gastrulation in 8 frames / Lecture notes / Gastrulation & neurulation color diagram
Lecture 7, Mar 8, Th. Neural induction and neurulation 79-80; 263-272; 336 (312-324; 375-381). PPT_slides Lecture notes
Lecture 8, Mar 13, Tu. Chick development and extraembryonic development 287-297; 480-482 (336-348; 501-503; 45). PPT_slides Lecture notes
Lecture 9, Mar 15, Th. Mammalian early development 300-313 (92-96; 348-368). PPT slides Lecture notes
REVIEWS, MARCH 20 AND 21 (5-7PM) VLSB.
Lecture 1, Mar 20, Tu.  Professor Richard Harland: Summary of Amniote Gastrulation; comments on mammalian gastrulation, Overview of organogenesis (Note this will not be included on Midterm 2)

Cick here for useful animations from the Brivanlou Lab.

Reviews:
March 20, Tu. 5-7pm 2030 VLSB and
March 21, We. 5-7pm 2031 VLSB.

Midterm 2: Thursday, March 22, 11:10-12:30. (note: Midterm 2 comes after Professor Harland’s Lecture 1 on March 20th)

 

III. Professor Richard Harland

Final third of the course: late development of vertebrates--organogenesis, cytodifferentiation. Lecture notes and reading assignments will be posted later.

Lecture 1, Mar 20, Tu.  Summary of Amniote Gastrulation; comments on mammalian gastrulation, Overview of organogenesis [see above]. Lecture notes
Mar 27, Tu.  Spring Break
Mar 29, Th.  Spring Break 
Lecture 2, Apr 03, Tu.  Neural Tube: induction, morphogenesis, pattern, differentiation. Lecture notes/ PPT_slides
Lecture 3, Apr 05, Th.  Brain formation, placodes, axon guidance. Lecture notes
Lecture 4, Apr 10, Tu. Spinal cord and neural tube formation. Neurite pathway connectivity Lecture notes PPT slides
Lecture 5, Apr 12, Th  Somite differentiation Lecture notes PPT slides
Lecture 6, Apr 17, Tu. Somites cont't. Neural crest. Lecture notes PPT slides
Lecture 7, Apr 19, Th. Nuclear transfer. Muscle Differentiation Lecture notes PPT presentation*
Lecture 8, Apr 24, Tu.  Kidney, reproductive system, vascular system Lecture notes <- (*) PPT presentation included on PPT from Lec 7
Lecture 9, Apr 26, Th. Endodermal derivatives. Kidney - Lecture notes - PPT presentation

RMH - Review sessionRecitation - 125 Li Ka Shing on Thursday, May 3rd from 11am to 12:30 pm <<<<<---- NEW!!!

Final Exam: Final Exam Group 13: Thursday, May 10, 2012, 8–11AM.