Meeting Times are listed below each paper!

Journal Club Nov 26/27 & Dec 3/4


Journal club presentations will presented by groups of two students. Each pair should pick and read a paper from this list and give a 15 minute presentation on the paper in class. Your main goal is to explain the important parts of the paper to your audience.
In the presentation the following points should be covered:

  1. A short summary of background information on the topic.
  2. The major question the paper is addressing.
  3. A summary of the major experiments and results (explain the relevant techniques).
  4. A short summary of the major conclusions drawn.


You should make your presentation understandable to your audience, who have not read the paper. You don't have to explain every little detail of the paper (that would take longer than 15 minutes!), but you should cover all important points. Make everything as clear as possible. Overheads should be used.



You may choose one of the following papers to present (if you already have a date you must select from that week):



List of Journal Club papers:

Link to PubMed (A search site for Scientific Journal Articles)

PubMed Guide

Week 14:

Journal Club 5

Apoptosis

“The Entericidin Locus of Escherichia coli and its Implications for Programmed Bacterial Cell Death”

Russell E. Bishop, Brenda K. Leskiw, Robert S. Hodges, Cyril M. Kay, and Joel H. Weiner

J. Mol. Biol. (1998) 280, 583-596

“The Caenorhabditis elegans cell-death protein CED-3 is a cysteine protease with substrate specificities similar to those of the human CPP32 protease”

Ding Xue, Shai Shaham, and H. Robert Horvitz

Genes & Dev. 1996 10:  1073-1083

 

Week 15:

Journal Club 6

Mitochondria and Respiration

 “Rates of Behavior and Aging Specified by Mitochondrial Function During Development”

Andrew Dillin, Ao-Lin Hsu, Nuno Arantes-Oliveira, Joshua Lehrer-Graiwer, Honor Hsin, Andrew G. Fraser, Ravi S. Kamath, Julie Ahringer, Cynthia Kenyon.

Science 298, 2398-2401 (2002)

Signal Transduction

“Function of the MAPK scaffold protein, Ste5, requires a cryptic PH domain”

Lindsay S. Garrenton, Susan L. Young and Jeremy Thorner

Genes & Dev. 2006 20:  1946-1958



This web site is updated by Tim Melton . Site modified Aug 2007.