Ph.D., Molecular Biology, 1983, Molecular Biology Institute, University of California, Los Angeles.
A.B., Biology, 1976, Middlebury College, Middlebury, Vermont, Cum laude.
Principal Scientist, 8/96-present, Viral Immunobiology, Chiron Vaccines, Chiron Corporation.
Visiting Scientist, 6/94-7/96, Viral Immunobiology, Chiron Biocine, Chiron Corporation, Emeryville, CA.
Assistant Research Virologist, 1993-1994, Cancer Research Institute, University of California, San Francisco.
Postdoctoral Research, 1989-1993, with Dr. Jay Levy, M.D., Cancer Research Institute, University of California, San Francisco.
Postdoctoral Research, 1984-1988, with Dr. Steven Beckendorf, Ph.D., Department of Molecular Biology, University of California, Berkeley.
Graduate Student, Molecular Biology, 1977-1983, with Dr. Kathleen Dixon, Ph.D., Department of Biologic Chemistry and Molecular Biology Institute, University of California, Los Angeles.
Scholar of the American Foundation for AIDS Research (AmFAR), 1990-1993.
American Cancer Society Senior Postdoctoral Fellow, 1986-1988.
Damon Runyon/Walter Winchell Cancer Fund Postdoctoral Fellow, 1984-1986.
National Institutes of Health Predoctoral Genetics Trainee, 1978-1982.
American Association for the Advancement of Science (AAAS)
International AIDS Society (IAS)
Klinger, J.M., S. Himathongkham, H. Legg, P.A. Luciw, and S.W. Barnett (1997). Infection of baboons with an SIV/HIV-1 chimeric virus constructed with and HIV-1 Thai subtype-E envelope. Submitted to AIDS.
Locher, C. P., D.J. Blackbourn, B.G. Herndier, G. Reyes-Teran, S. W. Barnett, K. Murthy, and J.A. Levy. Characteristics of HIV-2UC12 infection of baboons. Submitted to AIDS Res. and Hum. Retrov.
Locher, C. P., S.W. Barnett, B.G. Herndier, D. J. Blackbourn, G. Reyes-Teran, K.K. Murthy, K.M. Brasky, G. Hubbard, T. Reinhart, A. Haase, and J.A. Levy. Human immunodeficiency virus-2 infection in baboons is an animal model for human immunodeficiency virus pathogenesis in humans. In press, Arch. of Pathol. and Lab. Med.
Locher, C.P. D.J. Blackbourn, S.W. Barnett, K.K. Murthy, E.K. Cobb, S. Rouse, G. Greco, G. Reyes-Teran, K.M. Brasky, K.D. Carey, and J.A. Levy. Superinfection with HIV-2 can reactivate virus production in baboons but is contained by a CD8+ T cell antiviral response (1997). J. Infect. Diseases 176: 948-959.
Blackbourn, D. J., C.P. Locher, B. Ramachandran, S.W. Barnett, K.K. Murthy, K.D.Carey, K.M. Brasky, and J.A. Levy. CD8+ cells from HIV-2-infected baboons control HIV replication (1997). AIDS 11: 737-746.
Barnett, S.W., S. Rajasekar, H. Legg, B. Doe, D.H. Fuller, J.R. Haynes, C.M. Walker, and K S. Steimer (1997). Vaccination with HIV-1 gp120 DNA induces immune responses that are boosted by recombinant gp120 protein subunit. Vaccines 15: 869-873.
Fuller, D.H., M. Murphey-Corb., S.W. Barnett, and J.R. Haynes (1997). Enhancement ot immunodeficiency virus-specific immune responses in DNA-immunized rhesus macaques. Vaccines 15: 924-926.
Doe, B., M. Selby., S. Barnett, J. Baenziger, and C.M. Walker (1996). Induction of cytotoxic T lymphocytes by intramuscular immunization with plasmid DNA is facilitated by bone marrow-derived cells. Proc. Natl. Acad. Sci. USA 93: 8578-8583.
Fuller, D.H., M. Murphey-Corb, J. Clements, S.W. Barnett., and J.R. Haynes (1996). Induction of immunodeficiency virus-specific immune responses in Rhesus monkeys following gene gun-mediated DNA vaccination. J. Med. Primatol. 25: 236-241.
Barnett, S.W., H. Legg, Y. Sun, J. Klinger, D.J. Blackbourn, and J.A. Levy (1996). Molecular cloning of the HIV-2 strain that causes an AIDS-like disease in baboons. Virology 222: 257-261.
Weiss, C.D., S.W. Barnett, N. Cacalano, N. Killeen, D.R. Littman, and J.M. White. (1996). Studies of human immunodeficiency envelope glycoprotein-mediated fusion using a simple fluorescence assay. AIDS 10: 241-246.
Barnett, S.W., B.G. Herndier, K.K. Murthy, and J.A. Levy (1994). An AIDS-like condition induced in baboons by HIV-2. Science 266: 642-646.
Barnett, S.W., Quiroga, M., Evans, L., Werner, A., Dina, D., and J.A. Levy (1993). Distinguishing features of an infectious molecular clone of the highly divergent and noncytopathic human immunodeficiency virus type 2 UC1 strain. J. Virology 67: 1006-1014.
Barnett, S.W., Barboza, A., Wilcox, C.M., Forsmark, C., and J.A. Levy (1991). Characterization of human immunodeficiency virus type 1 strains from the bowel of infected individuals. Virology 182: 802-809.
Castro, B.A., S.W. Barnett, L.A. Evans, A. Barboza, H. Legg, and J.A. Levy (1990). Biological heterogeneity of human immunodeficiency virus type 2 (HIV-2) strains. Virology 178: 527-534.
Barnett, S.W., K. Flynn, M. Webster and S.K. Beckendorf (1990). Noncoordinate expression of Drosophila glue genes: Sgs-4 is expressed at many stages and in two different tissues. Developmental Biology 140: 362-373.
Shermoen, A.W., J. Heemskerk, S.W. Barnett, K. Flynn and S.K. Beckendorf (1987). Developmental regulation by an enhancer from the Sgs-4 gene of Drosophila melanogaster. EMBO J. 6: 207-214.
Barnett, S.W., E.M. Landaw and K. Dixon (1983). Test of models for replication of SV40 following UV irradiation. Biophys. J. 46: 307-321.
Dixon, K., S.W. Barnett, C.K. Lau and P.S. Stacks (1982). Cloning of SV40 HindIII restriction fragments into M13 bacteriophage. Gene 18: 97-100.
Barnett, S. W., S. Rajasekar, B. Doe, C.M. Walker, K. S. Steimer. Immunization with HIV-1 gp120 DNA in combination with recombinant gp120SF2 protein subunit induces vigorous antibody and cytotoxic T-lymphocyte responses.
Verschoor, E.J., P. Metra, H. Oostermeijer, P. ten Haaft, D. Fuller, S.W. Barnett, and J. L. Heeney. Comparison of immunogenicity and protective efficacy of HIV1SF2 gp120 DNA and adjuvanted protein subunit vaccines in rhesus macaques.
Himathongkham, S., J.M. Klinger, S.W. Barnett, and P.A. Luciw (1997). Chimeric SHIV with HIV-1 subtype-E (Thai) E envelope gene is restricted at an early step for replication in rhesus macaque lymphocytes.
Barnett, S. W., J. Klinger, H.S. Legg, M. Murphey Corb, and K..S. Steimer. Rhesus macaques immunized with recombinant gp120 from HIV-1SF2 are not protected from intravenous challenge with heterologous SIV/HIV chimera, SHIV33.
Fuller, D.H., M. Murphey-Corb., S.W. Barnett. Gene-gun based DNA immunization primes for the induction of vigorous immune responses in Rhesus macaques when followed by a recombinant subunit boost but does not protect against heterologous challenge with SHIV33.
Barker, E., S.W. Barnett, L. Stamatatos, and J.A. Levy (1995). Human immunodeficiency viruses. In The Retroviridae, Volume 4, Ed. J.A. Levy. Plenum Press, New York, pp. 1-96.
Barker, E., and S.W. Barnett (1994). Human immunodeficiency viruses. In Manual of Clinical Microbiology, Sixth Edition. Ed. A. Balows. American Society for Microbiology, Washington, D.C., pp. 1098-1114.
Barnett, S.W. and J.A. Levy (1990). Human immunodeficiency viruses. In Manual of Clinical Microbiology, Fifth Edition. Ed. A. Balows. American Society for Microbiology, Washington, D.C. pp. 1011-1023.
Mascola, J., T. VanCott, L. Loomis-Price, F. Sinangil, S. Barnett, J. McNeil, and D. Birx. Preclinical immunogenicity data of a clade E gp120: Comparison to clade B (SF2) gp120. 4th International Congress on AIDS in Asia and the Pacific, October 25-29, 1997, Manila, The Philippines.
Verschoor, E.J., P. Metra, H. Oostermeijer, P. ten Haaft, D. Fuller, S.W. Barnett, and J. L. Heeney (1997). Comparison of immunogenicity and protective efficacy of HIV1SF2 gp120 DNA and adjuvanted protein subunit vaccines in rhesus macaques. 15th Annual Symposium on Nonhuman Primate Models for AIDS, September 3-6, 1997, Seattle, WA..
Barnett, S.W., A.M. Duliege, F. Sinangil, C.M. Walker, L. Hansen, K. Boggio, and K.S. Steimer, HIV Vaccine Efforts at Chiron: Polynucleotide, Protein Subunit, and Prime/Boost Approaches. Invited speaker, 4th Conference on Retroviruses and Opportunistic Infections, January 22-26, 1997, Washington, D.C.
Klinger, J. M., H. Legg, P.A. Luciw, K.S. Steimer, and S.W. Barnett,. Development of an animal model for HIV-1 subtype E vaccine studies: Construction, characterization, and infectivity of a SHIV virus containing an HIV-1 Thai subtype E Envelope. 14th Annual Symposium on Nonhuman Primate Models for AIDS, October 23-26, 1996, Portland, OR.
Himathongkham, S., S. Barnett, J Klinger, and P.A. Luciw. Chimeric SHIV with HIV-1 Subtype E Envelope Gene is Restricted at an Early Step for Replication in Macaque Lymphocytes. 14th Annual Symposium on Nonhuman Primate Models for AIDS, October 23-26, 1996, Portland, OR.
Barnett, S.W., H. Legg, S. Rajasekar, J.M. Klinger, B. Doe, D.H. Fuller, J.R. Haynes, C.M. Walker, and K.S. Steimer. Immune responses to HIV DNA vaccination are boosted by recombinant protein subunit. 3rd International Conference on Engineered Vaccines for Cancer and AIDS, October 9-14, 1996, Hilton Head Island, South Carolina.
Barnett, S.W., S. Rajasekar, H. Legg, B. Doe, D.H. Fuller, J.R. Haynes, C.M. Walker, and K S. Steimer (1996). Vaccination with HIV DNA induces immune responses that are boosted by protein subunit. Oral presentation, Eighth Annual Meeting of the National Cooperative Vaccine Development Groups (NCVDG) for AIDS, February 11- 15, Bethesda, MD.
Barnett, S.W., J. M. Klinger, H. Legg, P. A. Luciw, M. Murphey-Corb, and K.S. Steimer (1996). Recombinant gp120/MF59 subunit immunization does not protect Rhesus macaques from intravenous challenge with heterologous SHIV33. Eighth Annual Meeting of NCVDG for AIDS, February 11- 15, Bethesda, MD.
Fuller, D.H., M. Murphey-Corb., S.W. Barnett, K. Steimer, and J.R. Haynes (1996). Gene-gun based DNA immunization primes for the induction of vigorous immune responses in Rhesus macaques when followed by a recombinant subunit or vaccinia boost. Eighth Annual Meeting of NCVDG for AIDS, February 11- 15, Bethesda, MD.
Locher, C.P., D.J. Blackbourn, K.K. Murthy, S.W. Barnett, K.M. Brasky, B. Herndier, T. Rienhardt, A. haase, and J.A. Levy. (1996). Pathogenic and immunologic consequences of HIV-2 serial passage in baboons. Eighth Annual Meeting of NCVDG for AIDS, February 11- 15, Bethesda, MD.
Barnett, S.W., S. Rajasekar, H. Legg, B. Doe, D.H. Fuller, J.R. Haynes, C.M. Walker, and K S. Steimer (1996). Vaccination with HIV DNA induces immune responses that are boosted by protein subunit. Oral presentation, International Meeting on Nucleic Acid Approaches for the Prevention of Infectious Diseases. February 5-7, Bethesda, MD.
Barnett, S.W., J. M. Klinger, H. Legg, P. J. Dailey, P. A. Luciw, M. Murphey-Corb, and K.S. Steimer (1995). Heterologous SHIV33 challenge of rgp120SF2/MF59 immunized Rhesus macaques. 13th Annual Symposium on Nonhuman Primate Models for AIDS. November 5-8, Monterey, CA.
Klinger, J.M., S.W. Barnett, Y.D. Sun, P.A. Luciw, and K.S. Steimer. Construction and characterization of SHIV chimeric viruses with HIV-1 subtype E Tat, Rev, and Envelope Sequences. 13th Annual Symposium on Nonhuman Primate Models for AIDS. November 5-8, Monterey, CA.
Locher, C.P. D.J.Blackbourn, K.K. Murthy, S.W. Barnett, K.M. Brasky, T.M. Butler, K. Rice, K.D. Carey, and J.A. Levy. Baboons infected with HIV-2 are resistant to superinfection. 13th Annual Symposium on Nonhuman Primate Models for AIDS. November 5-8, Monterey, CA.
Barnett, S.W., J. Klinger, S. Rajasekar, H. Legg, B. Doe, C.M. Walker, K.S. Steimer (1995). HIV vaccines: The next generation. Oral presentation, Laboratory of Tumor Cell Biology Annual Meeting, August, 27-September 2, 1995, Bethesda, MD. AIDS Res.Hum. Retrov. 11 (Suppl. 1): S135.
Bassler, K. D., P. Montbriand, S. Rajasekar, S.W. Barnett, K.S. Steimer, M. Bennett, J. Malone, M. Nantz, G.H. Rhodes, and R. Malone (1995). Genetic immunization: Effects of novel priming and boosting strategies. International Symposium on New Approaches to Vaccine Development, Vienna, Austria, April 11-14, 1995.
Bassler, K.D., S.W. Barnett, P. Montbriand, B. Doe, J.G. Malone, G.H. Rhodes, M.J. Bennett, C. Walker, P.A. Luciw, K.S. Steimer, R.W. Malone (1995). Development and testing of intramuscular and mucosal polynucleotide vaccines. 1995 International Symposium on Clinical Immunology, July 20-23, 1995, San Francisco, California.
Barnett, S.W., D.J. Blackbourn, B.G. Herndier, K Murthy, and J.A. Levy (1994). An AIDS-like condition is induced in baboons by HIV-2. Conference on Advances in AIDS Vaccine Development, Seventh NCVDG Meeting. Oral Presentation.
Klinger J., H.S. Legg , Y.D. Sun , J.A. Levy, and S.W. Barnett. (1994). Molecular characterization of HIV-2 strains that infect baboons. Conference on Advances in AIDS Vaccine Development, Seventh NCVDG Meeting.
Barnett, S.W., K Murthy, D.J. Blackbourn, B.G. Herndier, K Murthy, and J.A. Levy. (1994) HIV-2 infection of baboons: An animal model for HIV pathognesis and vaccine development. Abstracts of the 12th Annual Symposium on Nonhuman Primate Models for AIDS. J. Med. Primatol. 23: 266.
Barnett, S.W., K Murthy, D.J. Blackbourn, and J.A. Levy. (1993). HIV-2 infection of baboons: an animal model for vaccine development and studies of HIV pathogenesis. Conference on Advances in AIDS Vaccine Development, Sixth NCVDG Meeting. Oral Presentation.
Barnett, S.W., K Murthy, and J.A. Levy. (1993). HIV-2 infection of baboons: an animal model for persistence and pathogenesis. Keystone Symposia. J. Cell. Biochem. Supp. 17E , abstract Q400, p.58.
Barnett, S.W., M. Quiroga, A. Werner, and J.A. Levy. (1992). Biologic and molecular properties of an infectious molecular clone of the noncytopathic HIV-2UC1. 8th International Conference on AIDS, Amsterdam, the Netherlands, abstract PoA2041, Vol.2, pA9.
Barnett, S.W., M. Quiroga, A. Werner, and J.A. Levy. (1992). Biologic and molecular properties of an infectious molecular clone of the noncytopathic HIV-2UC1. Keystone Symposia. J. Cell. Biochem. Supp. 16E, abstract Q302, p.45.
Barnett, S.W., A. Werner, and J.A. Levy. (1992). Biologic and molecular studies of HIV-2 strains. 9th Annual Universitywide AIDS Research Program and Task Force on AIDS, March 12, 1992, San Francisco, CA.
Barnett, S.W., Quiroga, M., Evans, L., and J.A. Levy. Characterization of an infectious molecular clone of the noncytopathic HIV-2UC1. 10th Annual Meeting of the American Society for Virology, July 7-11, (1991), Colorado State University, Fort Collins, CO.
Barnett, S.W., Castro, B., Werner, A., and J.A. Levy (1991). Biologic and molecular studies of HIV-2. 8th Annual Universitywide AIDS Research Program and Task Force on AIDS, March 21, 1991, San Francisco, CA.
Barnett, S.W., Barboza, A., Wilcox, C.M., Forsmark, C., and J.A. Levy (1990). Characterization of HIV-1 strains recovered from the bowel. Oral presentation, 6th International Conference on AIDS, June 20-24, 1990, San Francisco, CA.
Beckendorf, S.K., T.A. Jongens, T. Fowler, A.W. Shermoen, S.W. Barnett, and M. Webster (1988). Regulation of the Sgs-4 glue gene: enhancer redundancy and precocious expression. Abstracts of the 29th Annual Drosophila conference: 25.
Barnett, S.W., K. Flynn, and S.K. Beckendorf (1987). Fusion gene strategy to identify trans-acting regulatory mutants of Sgs-4. Abstracts of the 28th Annual Drosophila Conference: 76.
Barnett, S.W., K. Flynn, and S.K. Beckendorf (1986). Fusion gene strategy to identify trans-acting regulatory mutants of Sgs-4 . Abstracts of the 27th Annual Drosophila Conference: 41.
Barnett, S.W., E.M. Landaw and K. Dixon (1983). Replication fork movement on UV damaged SV40 templates. Keystone Symposia. J. Cell. Biochem. Supp. 7b: 240.