MCB 110 - Fall 2007
General Biochemistry & Molecular Biology

PART 1 - Nucleic Acid Structure and DNA Metabolism
Tom Alber

MIDTERM 1 INFORMATION

Answer key to Midterm 1: [PDF]


  • Answer Key to Problem Set 1 - Nucleic Acid Structure
  • Answer Key to Problem Set 2 - DNA replication
  • Answer Key to Problem Set 3 - DNA packaging, analysis methods and bioinformatics
  • Answer Key to Problem Set 4 - DNA repair
  • Answer Key to 2005 Midterm
  • Answer Key to 2006 Midterm

  • LECTURE 1
    August 27
    Introduction to the Course.
    Nucleic Acid Structure

    Not your grandfather's DNA:Variations in DNA structure
    (Jeremy Thorner, Guest Lecturer)

    Slides
    * Powerpoint file (14.3 MB)
    * PDF (1.1 MB)

    LECTURE 2
    August 29
    (Twisted) Principles of DNA structure and recognition

    Slides
    * Powerpoint file (8.8 MB)
    * PDF (1.8 MB)

    LECTURE 3
    August 31
    DNA polymerases: poor enzymes doing half the job
    (James Berger, Guest Lecturer)

    Slides
    * Powerpoint file (4.4 MB)
    * PDF (680 KB)

    LECTURE 4
    September 5

    LECTURE 5
    September 7

    The DNA replication fork: collaborate or die

    Other replication factors: it takes a village

    Slides
    * Powerpoint file (8.4 MB)
    * PDF (1.2 MB)

    LECTURE 6
    September 10
    Replication origins and ends: regulation

    Slides
    * Powerpoint file - Version 2 (10.2 MB)
    * PDF (800 KB)

    LECTURE 7
    September 12

    LECTURE 8
    September 14

    You say you want a revolution: DNA analysis methods

    DNA analysis methods II

    Slides
    * Powerpoint file - Version 4 (7 MB)
    * PDF (664 KB)

    LECTURE 9
    September 17
    DNA wrap: Chromatin and chromosome structure

    Slides
    * Powerpoint file (6.9 MB)
    * PDF (896 KB)

    LECTURE 10
    September 19
    Genome structures: what's in a model (organism)

    Slides
    * Powerpoint file (4.5 MB)
    * PDF (556 KB)

    LECTURE 11
    September 21
    Genomics and Bioinformatics: Time machines and function

    Slides
    * Powerpoint file (1.8 MB)
    * PDF (508 KB)

    LECTURE 12
    September 24
    Human disease genes: risky science and the new "infinity"

    Slides
    * Powerpoint file (2.9 MB)
    * PDF (404 KB)

    LECTURE 13
    September 27

    LECTURE 14
    September 29

    DNA damage and repair: oops, ouch!

    Recombination and repair in cancer

    Slides
    * Powerpoint file (7 MB)
    * PDF (560 KB)



    webmonster
    Updated October 9, 2007
    http://mcb.berkeley.edu/courses/mcb110/ALBER/Part1.html