MIDTERM 1 INFORMATION Answer key to Midterm 1: [PDF]
LECTURE 1
August 27Introduction to the Course.
Nucleic Acid Structure
Not your grandfather's DNA:Variations in DNA structure
(Jeremy Thorner, Guest Lecturer)Slides
* Powerpoint file (14.3 MB)
* PDF (1.1 MB)
LECTURE 2
August 29(Twisted) Principles of DNA structure and recognition Slides
* Powerpoint file (8.8 MB)
* PDF (1.8 MB)
LECTURE 3
August 31DNA polymerases: poor enzymes doing half the job
(James Berger, Guest Lecturer)Slides
* Powerpoint file (4.4 MB)
* PDF (680 KB)
LECTURE 4
September 5LECTURE 5
September 7The DNA replication fork: collaborate or die Other replication factors: it takes a village
Slides
* Powerpoint file (8.4 MB)
* PDF (1.2 MB)
LECTURE 6
September 10Replication origins and ends: regulation Slides
* Powerpoint file - Version 2 (10.2 MB)
* PDF (800 KB)
LECTURE 7
September 12LECTURE 8
September 14You say you want a revolution: DNA analysis methods DNA analysis methods II
Slides
* Powerpoint file - Version 4 (7 MB)
* PDF (664 KB)
LECTURE 9
September 17DNA wrap: Chromatin and chromosome structure Slides
* Powerpoint file (6.9 MB)
* PDF (896 KB)
LECTURE 10
September 19Genome structures: what's in a model (organism) Slides
* Powerpoint file (4.5 MB)
* PDF (556 KB)
LECTURE 11
September 21Genomics and Bioinformatics: Time machines and function Slides
* Powerpoint file (1.8 MB)
* PDF (508 KB)
LECTURE 12
September 24Human disease genes: risky science and the new "infinity" Slides
* Powerpoint file (2.9 MB)
* PDF (404 KB)LECTURE 13
September 27LECTURE 14
September 29DNA damage and repair: oops, ouch! Recombination and repair in cancer
Slides
* Powerpoint file (7 MB)
* PDF (560 KB)